TY - JOUR
T1 - Carriage of multiple Streptococcus pneumoniae capsular types is frequent among children with invasive pneumococcal disease
AU - Félix, Sofia
AU - Henares, Desirée
AU - Muñoz-Almagro, Carmen
AU - Sá-Leão, Raquel
N1 - Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
PY - 2021/11
Y1 - 2021/11
N2 - Streptococcus pneumoniae (pneumococcus) is a human pathogen that colonizes the nasopharynx. We investigated serotype distribution in paired invasive and nasopharyngeal samples obtained from 57 children during invasive pneumococcal disease. Of 39 nasopharyngeal samples positive for pneumococci, 46.2% contained a serotype different from the one causing disease. This study reports a high frequency of pneumococcal multiple serotype carriage in children with invasive pneumococcal disease. Whether multiple serotype carriage is important for the onset and progress to pneumococcal infection warrants further investigation.
AB - Streptococcus pneumoniae (pneumococcus) is a human pathogen that colonizes the nasopharynx. We investigated serotype distribution in paired invasive and nasopharyngeal samples obtained from 57 children during invasive pneumococcal disease. Of 39 nasopharyngeal samples positive for pneumococci, 46.2% contained a serotype different from the one causing disease. This study reports a high frequency of pneumococcal multiple serotype carriage in children with invasive pneumococcal disease. Whether multiple serotype carriage is important for the onset and progress to pneumococcal infection warrants further investigation.
KW - Children
KW - Co-colonization
KW - Invasive pneumococcal disease
KW - Multiple serotype carriage
KW - Streptococcus pneumoniae
UR - http://www.scopus.com/inward/record.url?scp=85103681921&partnerID=8YFLogxK
U2 - 10.1007/s10096-021-04231-4
DO - 10.1007/s10096-021-04231-4
M3 - Article
C2 - 33797644
AN - SCOPUS:85103681921
SN - 0934-9723
VL - 40
SP - 2397
EP - 2401
JO - European Journal of Clinical Microbiology & Infectious Diseases
JF - European Journal of Clinical Microbiology & Infectious Diseases
IS - 11
ER -