Abstract
Leptomeningeal carcinomatosis is a rare complication of several types of cancer. There are many possible clinical features, and the diagnosis is made with brain imaging and cytological analysis of cerebrospinal fluid. Treatment is widely debated and, concerning overall survival, there does not seem to exist a treatment option which is definitely superior. The present work describes the case of a 53-year-old man diagnosed with leptomeningeal carcinomatosis secondary to lung adenocarcinoma, who was treated with whole brain radiation therapy and, upon relapse, with intrathecal chemotherapy, showing both an above-average overall survival and a high performance status.
Translated title of the contribution | Leptomeningeal carcinomatosis in a patient with lung adenocarcinoma treated with whole brain radiation therapy and intrathecal chemotherapy |
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Original language | Portuguese |
Pages (from-to) | 50-53 |
Number of pages | 4 |
Journal | Sinapse |
Volume | 21 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1 Jan 2021 |
Keywords
- Antineoplastic agents/ therapeutic use
- Cranial irradiation
- Lung neoplasms
- Meningeal carcinomatosis