Carbon Dioxide as Building Block in the Synthesis of the Anti-Infective Agent Hexamine

Cláudia C.L. Pereira, Marco D.R. Gomes da Silva, João P. Leal, Bernardo Monteiro

Research output: Contribution to journalArticle

Abstract

Electrochemical reduction of CO2 in a EMIMBF4 saturated solution in the presence of small amounts of the ionic liquid tetramethylguanidinium azide (TMGHN3) yield as major product the nonvolatile hexamethylenetetramine (HMTA) also known as hexamine or methenamine. Vestigial concentrations of other reduction products like CO, formic acid and acetic acid were also detected and quantified. Both Cu and Cu/Zn electrodes were tested and presented a similar efficiency towards HMTA production. Electrode modification during CO2 electro-reduction, including copper nanoparticle (CuNPs) deposition, is the key feature that facilitates HMTA synthesis.

Original languageEnglish
Pages (from-to)7178-7183
Number of pages6
JournalChemistrySelect
Volume3
Issue number25
DOIs
Publication statusPublished - 6 Jul 2018

Fingerprint

Methenamine
Anti-Infective Agents
Carbon Dioxide
formic acid
Ionic Liquids
Electrodes
Azides
Carbon Monoxide
Acetic Acid
Copper
Nanoparticles

Keywords

  • CO electro-reduction
  • Copper nanoparticles
  • hexamethylenetetramine
  • ionic liquid

Cite this

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title = "Carbon Dioxide as Building Block in the Synthesis of the Anti-Infective Agent Hexamine",
abstract = "Electrochemical reduction of CO2 in a EMIMBF4 saturated solution in the presence of small amounts of the ionic liquid tetramethylguanidinium azide (TMGHN3) yield as major product the nonvolatile hexamethylenetetramine (HMTA) also known as hexamine or methenamine. Vestigial concentrations of other reduction products like CO, formic acid and acetic acid were also detected and quantified. Both Cu and Cu/Zn electrodes were tested and presented a similar efficiency towards HMTA production. Electrode modification during CO2 electro-reduction, including copper nanoparticle (CuNPs) deposition, is the key feature that facilitates HMTA synthesis.",
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Carbon Dioxide as Building Block in the Synthesis of the Anti-Infective Agent Hexamine. / Pereira, Cláudia C.L.; Gomes da Silva, Marco D.R.; Leal, João P.; Monteiro, Bernardo.

In: ChemistrySelect, Vol. 3, No. 25, 06.07.2018, p. 7178-7183.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Carbon Dioxide as Building Block in the Synthesis of the Anti-Infective Agent Hexamine

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AU - Gomes da Silva, Marco D.R.

AU - Leal, João P.

AU - Monteiro, Bernardo

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Y1 - 2018/7/6

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