Canine leishmaniasis: pathological and ecological factors influencing transmission of infection

P Abranches, M. C D Silva-Pereira, F. M. Conceicao-Silva, G. M. Santos-Gomes, J. G. Janz

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200 Citations (Scopus)


Canine leishmaniasis was studied in 1,823 dogs from the Lisbon metropolitan region. The breeds most affected were doberman and German shepherd, independent of sex and use. Young adult (12.2%) and older dogs (14.7%) had higher prevalences of infection. Parasitological confirmation of serological diagnosis was higher in dogs with indirect fluorescent antibody test titer ≥1:512, indicating that parasitological patency is a late event. Exposure of Leishmania in lymph nodes is more efficient for parasitological confirmation (75.4% of cases). Frequent signs of disease were enlarged lymph nodes and onychogriphosis. However, 53.8% of the dogs with significant antibody titers (≥1:128) showed no symptom, suggesting that canine leishmaniasis has a prolonged asymptomatic period. This study confirmed the importance of the dog as the reservoir of visceral leishmaniasis.

Original languageEnglish
Pages (from-to)557-561
Number of pages5
JournalJournal Of Parasitology
VolumeVol. 77
Issue numbern.º 4
Publication statusPublished - 1 Aug 1991


  • Pathology
  • Portugal
  • Animal experiment
  • Animal tissue
  • Controlled study
  • Dog
  • Leishmaniasis
  • Nonhuman


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