Canine leishmaniasis: Pathological and ecological factors influencing transmission of infection

P Abranches, M. C D Silva-Pereira, F. M. Conceicao-Silva, G. M. Santos-Gomes, J. G. Janz

Research output: Contribution to journalArticle

175 Citations (Scopus)

Abstract

Canine leishmaniasis was studied in 1,823 dogs from the Lisbon metropolitan region. The breeds most affected were doberman and German shepherd, independent of sex and use. Young adult (12.2%) and older dogs (14.7%) had higher prevalences of infection. Parasitological confirmation of serological diagnosis was higher in dogs with indirect fluorescent antibody test titer ≥1:512, indicating that parasitological patency is a late event. Exposure of Leishmania in lymph nodes is more efficient for parasitological confirmation (75.4% of cases). Frequent signs of disease were enlarged lymph nodes and onychogriphosis. However, 53.8% of the dogs with significant antibody titers (≥1:128) showed no symptom, suggesting that canine leishmaniasis has a prolonged asymptomatic period. This study confirmed the importance of the dog as the reservoir of visceral leishmaniasis.

Original languageEnglish
Pages (from-to)557-561
Number of pages5
JournalJournal Of Parasitology
Volume77
Issue number4
DOIs
Publication statusPublished - 1991

Fingerprint

leishmaniasis
Infectious Disease Transmission
Leishmaniasis
disease transmission
Canidae
Dogs
dogs
antibody
Lymph Nodes
lymph nodes
Visceral Leishmaniasis
Antibodies
Leishmania
antibodies
Young Adult
visceral leishmaniasis
serodiagnosis
German Shepherd
dog
infection

Keywords

  • pathology
  • Portugal
  • animal experiment
  • animal tissue
  • article
  • controlled study
  • dog
  • leishmaniasis
  • nonhuman

Cite this

Abranches, P ; Silva-Pereira, M. C D ; Conceicao-Silva, F. M. ; Santos-Gomes, G. M. ; Janz, J. G. / Canine leishmaniasis : Pathological and ecological factors influencing transmission of infection. In: Journal Of Parasitology. 1991 ; Vol. 77, No. 4. pp. 557-561.
@article{f7fa945c50a64747a8bb3f5d26a645eb,
title = "Canine leishmaniasis: Pathological and ecological factors influencing transmission of infection",
abstract = "Canine leishmaniasis was studied in 1,823 dogs from the Lisbon metropolitan region. The breeds most affected were doberman and German shepherd, independent of sex and use. Young adult (12.2{\%}) and older dogs (14.7{\%}) had higher prevalences of infection. Parasitological confirmation of serological diagnosis was higher in dogs with indirect fluorescent antibody test titer ≥1:512, indicating that parasitological patency is a late event. Exposure of Leishmania in lymph nodes is more efficient for parasitological confirmation (75.4{\%} of cases). Frequent signs of disease were enlarged lymph nodes and onychogriphosis. However, 53.8{\%} of the dogs with significant antibody titers (≥1:128) showed no symptom, suggesting that canine leishmaniasis has a prolonged asymptomatic period. This study confirmed the importance of the dog as the reservoir of visceral leishmaniasis.",
keywords = "pathology, Portugal, animal experiment, animal tissue, article, controlled study, dog, leishmaniasis, nonhuman",
author = "P Abranches and Silva-Pereira, {M. C D} and Conceicao-Silva, {F. M.} and Santos-Gomes, {G. M.} and Janz, {J. G.}",
year = "1991",
doi = "10.2307/3283159",
language = "English",
volume = "77",
pages = "557--561",
journal = "Journal Of Parasitology",
issn = "0022-3395",
publisher = "Journal of Parasitology",
number = "4",

}

Canine leishmaniasis : Pathological and ecological factors influencing transmission of infection. / Abranches, P; Silva-Pereira, M. C D; Conceicao-Silva, F. M.; Santos-Gomes, G. M.; Janz, J. G.

In: Journal Of Parasitology, Vol. 77, No. 4, 1991, p. 557-561.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Canine leishmaniasis

T2 - Pathological and ecological factors influencing transmission of infection

AU - Abranches, P

AU - Silva-Pereira, M. C D

AU - Conceicao-Silva, F. M.

AU - Santos-Gomes, G. M.

AU - Janz, J. G.

PY - 1991

Y1 - 1991

N2 - Canine leishmaniasis was studied in 1,823 dogs from the Lisbon metropolitan region. The breeds most affected were doberman and German shepherd, independent of sex and use. Young adult (12.2%) and older dogs (14.7%) had higher prevalences of infection. Parasitological confirmation of serological diagnosis was higher in dogs with indirect fluorescent antibody test titer ≥1:512, indicating that parasitological patency is a late event. Exposure of Leishmania in lymph nodes is more efficient for parasitological confirmation (75.4% of cases). Frequent signs of disease were enlarged lymph nodes and onychogriphosis. However, 53.8% of the dogs with significant antibody titers (≥1:128) showed no symptom, suggesting that canine leishmaniasis has a prolonged asymptomatic period. This study confirmed the importance of the dog as the reservoir of visceral leishmaniasis.

AB - Canine leishmaniasis was studied in 1,823 dogs from the Lisbon metropolitan region. The breeds most affected were doberman and German shepherd, independent of sex and use. Young adult (12.2%) and older dogs (14.7%) had higher prevalences of infection. Parasitological confirmation of serological diagnosis was higher in dogs with indirect fluorescent antibody test titer ≥1:512, indicating that parasitological patency is a late event. Exposure of Leishmania in lymph nodes is more efficient for parasitological confirmation (75.4% of cases). Frequent signs of disease were enlarged lymph nodes and onychogriphosis. However, 53.8% of the dogs with significant antibody titers (≥1:128) showed no symptom, suggesting that canine leishmaniasis has a prolonged asymptomatic period. This study confirmed the importance of the dog as the reservoir of visceral leishmaniasis.

KW - pathology

KW - Portugal

KW - animal experiment

KW - animal tissue

KW - article

KW - controlled study

KW - dog

KW - leishmaniasis

KW - nonhuman

UR - http://www.scopus.com/inward/record.url?scp=0025923972&partnerID=8YFLogxK

U2 - 10.2307/3283159

DO - 10.2307/3283159

M3 - Article

VL - 77

SP - 557

EP - 561

JO - Journal Of Parasitology

JF - Journal Of Parasitology

SN - 0022-3395

IS - 4

ER -