Bone Tissue Adaptation - A Hierarchical Approach for Apparent Density and Trabecular Structure

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In this work a three-dimensional model for bone remodelling is developed taking into account the hierarchical structure of bone. The process of bone tissue adaptation is mathematically described with respect to functional demands, both mechanical and biological factors, to obtain the bone apparent density distribution (at the macroscale) and the trabecular structure (at the microscale). Previous results show that some microstructures with maximum mechanical efficiency do not match porosity levels observed in real bone [Coelho, 2006]. In this work biological requirements, such as porosity constraints, are carefully considered for a better representation of bone tissue adaptation.
Original languageUnknown
Pages (from-to)S125
JournalJournal Of Biomechanics
Volume41 Supplement 1
Issue numberJuly 2008
Publication statusPublished - 1 Jan 2008

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