Biocompatible locust bean gum mesoporous matrices prepared by ionic liquids and a scCO2 sustainable system

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9 Citations (Scopus)

Abstract

Locust bean gum (LBG) is a natural polymer that belongs to the increasingly attractive biodegradable polymers derived from natural sources. This polymer possesses a number of appealing features such as non-toxicity that confer it a high potential for the use in fields such as pharmacy and food industries. In this work, three methylimidazolium-based ionic liquids (ILs) were used as alternative media in the preparation of biocompatible LBG gel matrices. The process consists of dissolving the biomaterial in a selected IL followed by a multi-step solvent exchange using a mixture of water and ethanol. The final gel (internal surface areas ranging from 60 to 180 m2 g-1) is then dried using a semi-continuous high pressure CO2 extraction process. To the best of our knowledge this is the first time that LBG mesoporous gel matrices are reported using this efficient sustainable method.

Original languageEnglish
Pages (from-to)107700-107706
Number of pages7
JournalRCS Advances
Volume5
Issue number130
DOIs
Publication statusPublished - 2015

Keywords

  • DRUG-DELIVERY SYSTEMS
  • CONTROLLED-RELEASE
  • SODIUM ALGINATE
  • AEROGELS
  • IBUPROFEN
  • POLYSACCHARIDES
  • CELLULOSE
  • SILICA
  • GALACTOMANNAN
  • SOLVENTS

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