We present Bayesian methodologies and apply Markov chain sampling techniques for exploring normal mixture models with an unknown number of components in the context of magnetic resonance imaging (MRI) segmentation. The experiments show that by estimating the number of components using sample-based approaches based on variable dimension models the discriminating power of the estimated components is improved. Two different MCMC methods are compared to perform the segmentation of simulated magnetic resonance brain scans, the reversible jump MCMC model and the Dirichlet process (DP) mixture model. The preference given to the Dirichlet process mixture model is discussed.
da Silva, A. R. F., & DEE Group Author (2009). Bayesian mixture models of variable dimension for image segmentation. Computer Methods and Programs in Biomedicine, 94(1), 1-14. https://doi.org/10.1016/j.cmpb.2008.05.010