@inbook{15dfcf9b48004adb9fd65c0e244d7113,
title = "Bacterial Small RNAs: Diversity of Structure and Function",
abstract = "Small non-coding RNAs (sRNAs) are key post-transcriptional regulators of gene expression in bacteria, with a diversity of origins, sequences, structures, and modes of action among their members. The variety within these regulatory RNAs makes it difficult to unify this remarkable heterogeneous class of RNA molecules. Structural determinants along with nucleotide sequence play important roles in defining the sRNA ability to interact with their targets. Most sRNAs bind to mRNA targets, either acting as repressors or activators. Nevertheless, the sRNAs themselves are subject to post-transcriptional regulation, either by ribonucleases, RNA chaperones, and other RNA-binding proteins, as well as RNA sponges. In this chapter we summarize the information on structure and function of bacterial sRNAs and provide several examples to better illustrate the broad diversity of this class of regulatory RNAs.",
keywords = "CRISPR, Hfq, Non-coding RNA, Regulatory RNA, RNA sequence, RNA structure, RNA-RNA interaction, Sponge RNA, sRNA",
author = "Sousa, {Jo{\~a}o Pedro} and Silva, {Alda Filipa Queir{\'o}s} and Arraiano, {Cec{\'i}lia Maria} and Andrade, {Jos{\'e} Marques}",
note = "Funding Information: Acknowledgements This work was supported by FCT—Funda{\c c}{\~a}o para a Ci{\^e}ncia e a Tecnologia, I.P., through: MOSTMICRO-ITQB R&D Unit (UIDB/04612/2020, UIDP/04612/ 2020); LS4FUTURE Associated Laboratory (LA/P/0087/2020); Grant PTDC/BIA-MIC/32525/ 2017 to JMA; Doctoral Fellowships to AFQS (UI/BD/153390/2022) and JPS (2022.12475.BD). Publisher Copyright: {\textcopyright} The Author(s), under exclusive license to Springer Nature Switzerland AG 2023.",
year = "2023",
month = nov,
day = "4",
doi = "10.1007/978-3-031-36390-0_12",
language = "English",
isbn = "978-3-031-36389-4",
volume = "14",
series = "RNA Technologies",
publisher = "Springer Medizin",
pages = "259--277",
booktitle = "RNA Technologies",
}
