TY - JOUR
T1 - Bacterial nitrate reductases: molecular and biological aspects of nitrate reduction
AU - González, P. J.
AU - Correia, C.
AU - Moura, Isabel
AU - Brondino, C. D.
AU - Moura, J. J. G.
N1 - P.J.G. thanks Fundação para a Ciência e Tecnologia for funding (Grant SFRP/BD/10825/2002). C.D.B. and J.J.G.M. thank SECYT (Argentina) and GRICES (Portugal) by a bilateral collaborative grant. Work supported by Projects EC HPRN-CT-1999-00084, POCTI/1999/BME/35078, and POCTI/BME/36152/99 in Portugal, and CAI + D (UNL), PIP No. 02559/2000 (CONICET) and PICT 2003-06-13872 (SEPCyT) in Argentina.
PY - 2006/5/1
Y1 - 2006/5/1
N2 - Nitrogen is a vital component in living organisms as it participates in the making of essential biomolecules such as proteins, nucleic acids, etc. In the biosphere, nitrogen cycles between the oxidation states +V and -III producing many species that constitute the biogeochemical cycle of nitrogen. All reductive branches of this cycle involve the conversion of nitrate to nitrite, which is catalyzed by the enzyme nitrate reductase. The characterization of nitrate reductases from prokaryotic organisms has allowed us to gain considerable information on the molecular basis of nitrate reduction. Prokaryotic nitrate reductases are mononuclear Mo-containing enzymes sub-grouped as respiratory nitrate reductases, periplasmic nitrate reductases and assimilatory nitrate reductases. We review here the biological and molecular properties of these three enzymes along with their gene organization and expression, which are necessary to understand the biological processes involved in nitrate reduction.
AB - Nitrogen is a vital component in living organisms as it participates in the making of essential biomolecules such as proteins, nucleic acids, etc. In the biosphere, nitrogen cycles between the oxidation states +V and -III producing many species that constitute the biogeochemical cycle of nitrogen. All reductive branches of this cycle involve the conversion of nitrate to nitrite, which is catalyzed by the enzyme nitrate reductase. The characterization of nitrate reductases from prokaryotic organisms has allowed us to gain considerable information on the molecular basis of nitrate reduction. Prokaryotic nitrate reductases are mononuclear Mo-containing enzymes sub-grouped as respiratory nitrate reductases, periplasmic nitrate reductases and assimilatory nitrate reductases. We review here the biological and molecular properties of these three enzymes along with their gene organization and expression, which are necessary to understand the biological processes involved in nitrate reduction.
KW - Assimilatory nitrate reductase
KW - Mononuclear Mo-containing enzymes
KW - Nitrogen cycle
KW - Periplasmic nitrate reductase
KW - Respiratory nitrate reductase
UR - http://www.scopus.com/inward/record.url?scp=33646489626&partnerID=8YFLogxK
U2 - 10.1016/j.jinorgbio.2005.11.024
DO - 10.1016/j.jinorgbio.2005.11.024
M3 - Review article
C2 - 16412515
AN - SCOPUS:33646489626
SN - 0162-0134
VL - 100
SP - 1015
EP - 1023
JO - Journal of Inorganic Biochemistry
JF - Journal of Inorganic Biochemistry
IS - 5-6
T2 - 12th International Conference on Biological Inorganic Chemistry
Y2 - 31 July 2005 through 5 August 2005
ER -