Assessment of risk factors for in-hospital mortality after intensive care unit discharge

Ins Arajo; João Gonçalves-Pereira; Sofia Teixeira; Raquel Nazareth; Joana Silvestre; Vtor Mendes; Camila Tapadinhas; Pedro Póvoa

doi:10.3109/1354750X.2012.654407

Assessment of risk factors for in-hospital mortality after intensive care unit discharge

Ins Arajo, João Gonçalves-Pereira, Sofia Teixeira, Raquel Nazareth, Joana Silvestre, Vtor Mendes, Camila Tapadinhas, Pedro Póvoa

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

Context: Post-intensive care unit (ICU) mortality predictors are unknown. Objective: To assess post-ICU in-hospital mortality predictors. Materials and methods: Analysis of 296 patients discharged alive from a medical-surgical ICU during an 18-month period. Results: Post-ICU in-hospital mortality was 22.6%. Nonsurvivors had significantly higher Charlson comorbidity score and more often had a tracheostomy. C-reactive protein (CRP) "alert measurement", ≥ 6mg/dL, independently discriminated survivors from nonsurvivors. Discussion: A CRP "alert measurement" or the need for tracheostomy may be used to identify patients with high risk of dying after ICU discharge. Conclusions: Charlson comorbidity score, CRP and tracheostomy predicted post-ICU in-hospital mortality.

Original language	English
Pages (from-to)	180-185
Number of pages	6
Journal	Biomarkers
Volume	17
Issue number	2
DOIs	https://doi.org/10.3109/1354750X.2012.654407
Publication status	Published - Mar 2012

Keywords

C-reactive protein
Charlson comorbidity score
ICU patient discharge
Mortality
Tracheostomy

Access to Document

10.3109/1354750X.2012.654407

Cite this

@article{8cac2c430f4a4bb58aa7b4bf767125de,

title = "Assessment of risk factors for in-hospital mortality after intensive care unit discharge",

abstract = "Context: Post-intensive care unit (ICU) mortality predictors are unknown. Objective: To assess post-ICU in-hospital mortality predictors. Materials and methods: Analysis of 296 patients discharged alive from a medical-surgical ICU during an 18-month period. Results: Post-ICU in-hospital mortality was 22.6%. Nonsurvivors had significantly higher Charlson comorbidity score and more often had a tracheostomy. C-reactive protein (CRP) {"}alert measurement{"}, ≥ 6mg/dL, independently discriminated survivors from nonsurvivors. Discussion: A CRP {"}alert measurement{"} or the need for tracheostomy may be used to identify patients with high risk of dying after ICU discharge. Conclusions: Charlson comorbidity score, CRP and tracheostomy predicted post-ICU in-hospital mortality.",

keywords = "C-reactive protein, Charlson comorbidity score, ICU patient discharge, Mortality, Tracheostomy",

author = "Ins Arajo and Jo{\~a}o Gon{\c c}alves-Pereira and Sofia Teixeira and Raquel Nazareth and Joana Silvestre and Vtor Mendes and Camila Tapadinhas and Pedro P{\'o}voa",

year = "2012",

month = mar,

doi = "10.3109/1354750X.2012.654407",

language = "English",

volume = "17",

pages = "180--185",

journal = "Biomarkers",

issn = "1354-750X",

publisher = "Informa Healthcare",

number = "2",

}

TY - JOUR

T1 - Assessment of risk factors for in-hospital mortality after intensive care unit discharge

AU - Arajo, Ins

AU - Gonçalves-Pereira, João

AU - Teixeira, Sofia

AU - Nazareth, Raquel

AU - Silvestre, Joana

AU - Mendes, Vtor

AU - Tapadinhas, Camila

AU - Póvoa, Pedro

PY - 2012/3

Y1 - 2012/3

N2 - Context: Post-intensive care unit (ICU) mortality predictors are unknown. Objective: To assess post-ICU in-hospital mortality predictors. Materials and methods: Analysis of 296 patients discharged alive from a medical-surgical ICU during an 18-month period. Results: Post-ICU in-hospital mortality was 22.6%. Nonsurvivors had significantly higher Charlson comorbidity score and more often had a tracheostomy. C-reactive protein (CRP) "alert measurement", ≥ 6mg/dL, independently discriminated survivors from nonsurvivors. Discussion: A CRP "alert measurement" or the need for tracheostomy may be used to identify patients with high risk of dying after ICU discharge. Conclusions: Charlson comorbidity score, CRP and tracheostomy predicted post-ICU in-hospital mortality.

AB - Context: Post-intensive care unit (ICU) mortality predictors are unknown. Objective: To assess post-ICU in-hospital mortality predictors. Materials and methods: Analysis of 296 patients discharged alive from a medical-surgical ICU during an 18-month period. Results: Post-ICU in-hospital mortality was 22.6%. Nonsurvivors had significantly higher Charlson comorbidity score and more often had a tracheostomy. C-reactive protein (CRP) "alert measurement", ≥ 6mg/dL, independently discriminated survivors from nonsurvivors. Discussion: A CRP "alert measurement" or the need for tracheostomy may be used to identify patients with high risk of dying after ICU discharge. Conclusions: Charlson comorbidity score, CRP and tracheostomy predicted post-ICU in-hospital mortality.

KW - C-reactive protein

KW - Charlson comorbidity score

KW - ICU patient discharge

KW - Mortality

KW - Tracheostomy

UR - http://www.scopus.com/inward/record.url?scp=84857885370&partnerID=8YFLogxK

U2 - 10.3109/1354750X.2012.654407

DO - 10.3109/1354750X.2012.654407

M3 - Article

C2 - 22324487

AN - SCOPUS:84857885370

SN - 1354-750X

VL - 17

SP - 180

EP - 185

JO - Biomarkers

JF - Biomarkers

IS - 2

ER -

Assessment of risk factors for in-hospital mortality after intensive care unit discharge

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this