Argon-plasma treatment in benign metastasizing leiomyoma of the lung: A case report

A. Bugalho, A. Oliveira, J. Semedo, I. Lourenço, L. Carreiro

Research output: Contribution to journalLetterpeer-review


Benign metastasizing leiomyoma (BML) refers to benign pulmonary neoplasm associated with a previous or coincident history of uterine leiomyomata. We report the case of a 56-year-old postmenopausal woman with a 4-year history of multiple benign leiomyomatous lesions in bilateral lungs and the uterus. The tumor cells from the lungs and uterus were focally immunoreactive for HMB-45 antibody and progesterone receptor. Immunoreactivity to HMB-45 is well known in smooth muscle cells of hamartomatous neoplasms, such as angiomyolipoma and lymphangioleiomyomatosis, but has not been reported in BML previously. These features suggest a multifocal hamartomatous histogenesis rather than metastasis in the present case.

Original languageEnglish
Pages (from-to)948-951
Number of pages4
JournalJournal of the Formosan Medical Association
Issue number12
Publication statusPublished - 1 Jan 2000


  • Benign metastasizing leiomyoma
  • Hamartoma
  • HMB-45
  • Progesterone receptor


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