Antibacterial properties of compounds isolated from Carpobrotus edulis.

Ana Martins, A. Vasas, Miguel Viveiros Bettencourt, J Molnár , J. Hohmann, Leonard Amaral

Research output: Contribution to journalArticlepeer-review

34 Citations (Scopus)


Several compounds isolated from the plant Carpobrotus edulis were evaluated for their activity against multidrug-resistant (MDR) bacteria and their efflux pump systems. Amongst the compounds isolated, six compounds were tested, namely uvaol, -amyrin, oleanolic acid, catechin, epicatechin and monogalactosyldiacylglycerol. Oleanolic acid presented high antibacterial activity against a large number of bacterial strains. The triterpene uvaol was the most active compound for modulation of efflux activity by MDR Gram-positive strains.
Original languageEnglish
Pages (from-to)438-444
JournalInternational Journal Of Antimicrobial Agents
Issue number5
Publication statusPublished - 1 Jan 2011


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