An enzymatic route to a benzocarbazole framework using bacterial CotA laccase

Ana Catarina Sousa; M. Fátima M M Piedade; Ligia Maria Martins; M. Paula Robalo

doi:10.1039/c4gc02511c

An enzymatic route to a benzocarbazole framework using bacterial CotA laccase

Ana Catarina Sousa, M. Fátima M M Piedade, Ligia Maria Martins, M. Paula Robalo

Instituto de Tecnologia Química e Biológica António Xavier (ITQB)

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

The CotA laccase-catalysed oxidation of the meta,para-disubstituted arylamine 2,4-diaminophenyldiamine delivers, under mild reaction conditions, a benzocarbazole derivative (1) (74% yield), a key structural motif of a diverse range of applications. This work extends the scope of aromatic frameworks obtained using these enzymes and represents a new efficient and clean method to construct in one step C-C and C-N bonds. This journal is

Original language	English
Pages (from-to)	1429-1433
Number of pages	5
Journal	Green Chemistry
Volume	17
Issue number	3
DOIs	https://doi.org/10.1039/c4gc02511c
Publication status	Published - 1 Mar 2015

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An enzymatic route to a benzocarbazole framework using bacterial CotA laccase

Abstract

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