TY - GEN
T1 - Adsorption of Triclosan on Sensors Based on PAH/PAZO Thin-Films: The Effect of pH
AU - Pereira-da-Silva, João
AU - Zagalo, Paulo M.
AU - Magalhães-Mota, Gonçalo
AU - Ribeiro, Paulo A.
AU - Raposo, Maria
N1 - info:eu-repo/grantAgreement/FCT/5876/147412/PT#
FEDER, through Programa Operacional Factores de Competitividade–COMPETE and Fundação para a Ciência e a Tecnologia–FCT, by the project PTDC/FIS-NAN/0909/2014 and for the Portuguese research Grant No. PEst-OE/FIS/UI0068/2011.
J. Pereira-da-Silva and P.M. Zagalo acknowledge the fellowships PD/BD/142768/2018 and PD/BD/142767/2018 from RABBIT Doctoral Programme, respectively.
PY - 2020
Y1 - 2020
N2 - Triclosan (TCS) is a broad-spectrum antimicrobial, preservative agent widely used in pharmaceuticals and personal care products, considered as a troubling contaminant from the environmental point of view because of its toxicity, bacterial resistance promotion, and estrogenic effects. Under this compliance, the pernicious presence of TCS in the environment is requiring the development of molecular dedicated sensors, which in turn leads to the need to find adequate molecular systems capable of giving rise to a transduction. In this work, in order to investigate the affinity of TCS to common polyelectrolytes in an aqueous environment the adsorption of TCS on thin layer-by-layer (LbL) films of poly(1-(4-(3-carboxy-4-hydroxyphenylazo) benzene sulfonamido) -1,2ethanediyl, sodium salt) (PAZO) and poly (allylamine hydrochloride) (PAH) polyelectrolytes at different values of pH of the solution and changing the outer layer, PAZO and PAH, was investigated. Results demonstrated that the PAH layer is the most indicated to better adsorb TCS molecules. These results are of great importance for the development of TCS sensors based on LbL films, since it indicates that the outer layers of LbL films should be positive electrically charged.
AB - Triclosan (TCS) is a broad-spectrum antimicrobial, preservative agent widely used in pharmaceuticals and personal care products, considered as a troubling contaminant from the environmental point of view because of its toxicity, bacterial resistance promotion, and estrogenic effects. Under this compliance, the pernicious presence of TCS in the environment is requiring the development of molecular dedicated sensors, which in turn leads to the need to find adequate molecular systems capable of giving rise to a transduction. In this work, in order to investigate the affinity of TCS to common polyelectrolytes in an aqueous environment the adsorption of TCS on thin layer-by-layer (LbL) films of poly(1-(4-(3-carboxy-4-hydroxyphenylazo) benzene sulfonamido) -1,2ethanediyl, sodium salt) (PAZO) and poly (allylamine hydrochloride) (PAH) polyelectrolytes at different values of pH of the solution and changing the outer layer, PAZO and PAH, was investigated. Results demonstrated that the PAH layer is the most indicated to better adsorb TCS molecules. These results are of great importance for the development of TCS sensors based on LbL films, since it indicates that the outer layers of LbL films should be positive electrically charged.
KW - Adsorption
KW - PAH
KW - pH
KW - Thin-film
KW - Triclosan
UR - http://www.scopus.com/inward/record.url?scp=85082133916&partnerID=8YFLogxK
U2 - 10.1007/978-3-030-34585-3_29
DO - 10.1007/978-3-030-34585-3_29
M3 - Conference contribution
AN - SCOPUS:85082133916
SN - 978-3-030-34584-6
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 319
EP - 325
BT - Computational Intelligence Methods for Bioinformatics and Biostatistics - 15th International Meeting, CIBB 2018, Revised Selected Papers
A2 - Raposo, Maria
A2 - Ribeiro, Paulo
A2 - Sério, Susana
A2 - Staiano, Antonino
A2 - Ciaramella, Angelo
PB - Springer
CY - Cham
T2 - 15th International Conference on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2018
Y2 - 6 September 2018 through 8 September 2018
ER -