Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study

Enrica Menditto, Elisio Costa, Luis Midao, Sinthia Bosnic-Anticevich, Ettore Novellino, Slawomir Bialek, Vitalis Briedis, Alpana Mair, Rojin Rajabian-Soderlund, Sylvie Arnavielhe, Anna Bedbrook, Wienczyslawa Czarlewski, Isabella Annesi-Maesano, Josep M. Anto, Philippe Devillier, Govert De Vries, Thomas Keil, Aziz Sheikh, Valentina Orlando, Desiree Larenas-Linnemann & 478 others Lorenzo Cecchi, Giulia De Feo, M. Illario, Cristiana Stellato, Joao Fonseca, Joao Malva, Mario Morais-Almeida, Ana Maria Pereira, Ana Maria Todo-Bom, Violeta Kvedariene, Arunas Valiulis, Karl Christian Bergmann, Ludger Klimek, Ralph Moesges, Oliver Pfaar, Torsten Zuberbier, Vicky Cardona, Joaquim Mullol, Nikos G. Papadopoulos, Emmanuel P. Prokopakis, Mike Bewick, Dermot Ryan, Regina E. Roller-Wirnsberger, Peter Valentin Tomazic, Alvaro A. Cruz, Piotr Kuna, Boleslaw Samolinski, Wytske J. Fokkens, Sietze Reitsma, Isabelle Bosse, Jean-Francois Fontaine, Daniel Laune, Tari Haahtela, Sanna Toppila-Salmi, Claus Bachert, Peter W. Hellings, Erik Melen, Magnus Wickman, Carsten Bindslev-Jensen, Esben Eller, Robyn E. O'Hehir, Cemal Cingi, Bilun Gemicioglu, Omer Kalayci, Juan Carlos Ivancevich, Jean Bousquet, J. Bousquet, P. W. Hellings, W. Aberer, I. Agache, C. A. Akdis, M. Akdis, M. R. Aliberti, R. Almeida, F. Amat, R. Angles, I. Annesi-Maesano, I. J. Ansotegui, J. M. Anto, S. Arnavielle, E. Asayag, A. Asarnoj, H. Arshad, F. Avolio, E. Bacci, C. Bachert, I. Baiar-Dini, C. Barbara, M. Barbagallo, I. Baroni, B. A. Barreto, X. Basagana, E. D. Bateman, M. Bedolla-Barajas, A. Bedbrook, M. Bewick, B. Beghe, E. H. Bel, K. C. Bergmann, K. S. Bennoor, M. Benson, L. Bertorello, A. Z. Bialoszewski, T. Bieber, S. Bialek, C. Bindslev-Jensen, L. Bjermer, H. Blain, F. Blasi, A. Blua, M. Bochenska Marciniak, I. Bogus-Buczynska, A. L. Boner, M. Bonini, S. Bonini, C. S. Bosnic-Anticevich, I. Bosse, J. Bouchard, L. P. Boulet, R. Bourret, Pj Bousquet, F. Braido, V. Briedis, C. E. Brightling, J. Brozek, C. Bucca, R. Buhl, R. Buonaiuto, C. Panaitescu, M. T. Burguete Cabanas, E. Burte, A. Bush, F. Caballero-Fonseca, D. Caillaud, D. Caimmi, M. A. Calderon, P. A. M. Camargos, T. Camuzat, G. Canfora, G. W. Canonica, V. Cardona, K. H. Carlsen, P. Carreiro-Martins, A. M. Carriazo, W. Carr, C. Cartier, T. Casale, G. Castellano, L. Cecchi, A. M. Cepeda, N. H. Chavannes, Y. Chen, R. Chiron, T. Chivato, E. Chkhartishvili, A. G. Chuchalin, K. F. Chung, M. M. Ciaravolo, A. Ciceran, C. Cingi, G. Ciprandi, A. C. Carvalho Coehlo, L. Colas, E. Colgan, J. Coll, D. Conforti, J. Correia De Sousa, R. M. Cortes-Grimaldo, F. Corti, E. Costa, Mc Costa-Dominguez, F. Al Courbis, L. Cox, M. Crescenzo, A. A. Cruz, A. Custovic, W. Czarlewski, S. E. Dahlen, D'Amato, C. Dario, J. da Silva, Y. Dauvilliers, U. Darsow, F. De Blay, G. De Carlo, T. Dedeu, M. De Fatima Emerson, G. De Feo, G. De Vries, B. De Martino, N. P. Motta Rubina, D. Deleanu, P. Demoly, Ja Denburg, P. Devillier, S. Di Capua Ercolano, N. Di Carluccio, A. Didier, D. Dokic, M. G. Dominguez-Silva, H. Douagui, G. Dray, R. Dubakiene, S. R. Durham, G. Du Toit, M. S. Dykewicz, Y. El-Gamal, P. Eklund, E. Eller, R. Emuzyte, J. Farrell, A. Farsi, J. Ferreira, Jr. De Mello, J. Ferrero, A. Fink-Wagner, A. Fiocchi, W. J. Fok-Kens, Ja Fonseca, J. F. Fontaine, S. Forti, J. M. Fuentes-Perez, J. L. Galvez-Romero, A. Gamkrelidze, J. Garcia-Aymerich, C. Y. Garcia-Cobas, M. H. Garcia-Cruz, B. Gemicioglu, S. Genova, G. Christoff, J. E. Gereda, R. Gerth Van Wijk, R. M. Gomez, J. Gomez-Vera, S. Gonzalez Diaz, M. Gotua, I. Grisle, M. Guidacci, Na Guldemond, Z. Gutter, Ma Guzman, T. Haahtela, J. Hajjam, L. Hernandez, JO'B Houri-Hane, Y. R. Huerta-Villalobos, M. Humbert, G. Iaccarino, M. Illario, Z. Ispayeva, J. C. Ivancevich, Ej Jares, E. Jassem, S. L. Johnston, G. Joos, K. S. Jung, J. Just, M. Jutel, I. Kaidashev, O. Kalayci, A. F. Kalyoncu, J. Karjalainen, P. Kardas, T. Keil, P. K. Keith, M. Khaitov, N. Khaltaev, J. Kleine-Tebbe, L. Klimek, M. L. Kowalski, M. Kuitunen, I. Kull, P. Kuna, M. Kupczyk, V. Kvedariene, E. Krzych-Falta, P. Lacwik, D. Larenas-Linnemann, D. Laune, D. Lauri, J. Lavrut, L. T. T. Le, M. Lessa, G. Levato, J. Li, P. Lieberman, A. Liplec, B. Lipworth, K. C. Lodrup Carlsen, R. Louis, O. Lourenco, J. A. Luna-Pech, A. Magnan, B. Mahboub, D. Maier, A. Mair, I. Majer, J. Malva, E. Mandajieva, P. Manning, E. De Manuel Keenoy, G. D. Marshall, M. R. Masjedi, J. F. Maspero, E. Mathieu-Dupas, J. J. Matta Campos, Al Matos, M. Maurer, S. Mavale-Manuel, O. Mayora, M. A. Medina-Avalos, E. Melen, E. Melo-Gomes, Eo Meltzer, E. Menditto, J. Mercier, N. Miculinic, F. Mihaltan, B. Milenkovic, G. Moda, M. D. Mogica-Martinez, Y. Mohammad, I. Momas, S. Monte-Fort, R. Monti, D. Mora Bogado, M. Morais-Almeida, Morato-Castro, R. Mosges, A. Mota-Pinto, P. Moura Santo, J. Mullol, L. Munter, A. Muraro, R. Murray, R. Naclerio, R. Nadif, M. Nalin, L. Napoli, L. Namazova-Baranova, H. Neffen, V. Niedeberger, K. Nekam, A. Neou, A. Nieto, L. Nogueira-Silva, M. Nogues, E. Novellino, Td Nyembue, Re O'Hehir, C. Odzhakova, K. Ohta, Y. Okamoto, K. Okubo, G. L. Onorato, M. Ortega Cisneros, S. Ouedraogo, I. Pali-Scholl, S. Palkonen, P. Panzner, N. G. Papadopoulos, H. S. Park, A. Papi, G. Passalacqua, E. Paulino, R. Pawankar, S. Pedersen, J. L. Pepin, A. M. Pereira, M. Persico, O. Pfaar, J. Phillips, R. Picard, B. Pigearias, I. Pin, C. Pitsios, D. Plavec, W. Pohl, T. A. Popov, F. Portejoie, P. Potter, A. C. Pozzi, D. Price, E. P. Prokopakis, R. Puy, B. Pugin, R. E. Pulido Ross, M. Przemecka, K. F. Rabe, F. Raciborski, R. Raja-Bian-Soderlund, S. Reitsma, I. Ribeirinho, J. Rimmer, D. Riv-Ero-Yeverino, J. A. Rizzo, M. C. Rizzo, C. Robalo-Cordeiro, F. Rodenas, X. Rodo, M. Rodriguez Gonzalez, L. Rodriguez-Manas, C. Rolland, S. Rodrigues Valle, M. Roman Rodriguez, A. Romano, E. Rodriguez-Zagal, G. Rolla, R. E. Roller-Wirnsberger, M. Romano, J. Rosado-Pinto, N. Rosario, M. Rottem, D. Ryan, H. Sagara, J. Salimaki, B. Samolinski, M. Sanchez-Borges, J. Sastre-Dominguez, G. K. Scadding, H. J. Schunemann, N. Scichilone, P. Schmid-Grendelmeier, F. S. Serpa, S. Shamai, A. Sheikh, M. Sierra, F. E. R. Simons, V. Sir-Oux, J. C. Sisul, I. Skrindo, D. Sole, D. Somekh, M. Sonder-Mann, T. Sooronbaev, M. Sova, M. Sorensen, M. Sorlini, O. Spranger, C. Stellato, R. Stelmach, R. Stukas, J. Sunyer, J. Strozek, A. Szylling, Jn Tebyrica, M. Thibaudon, T. To, A. Todo-Bom, P. V. Tomazic, S. Toppila-Salmi, U. Trama, M. Triggiani, C. Suppli Ulrik, M. Urrutia-Pereira, R. Valenta, A. Valero, A. Valiulis, E. Valovirta, M. Van Eerd, E. Van Ganse, M. Van Hague, O. Vandenplas, M. T. Ventura, G. Vezzani, T. Vasankari, A. Vatrella, M. T. Verissimo, F. Viart, G. Viegi, D. Vicheva, T. Vontetsianos, M. Wagenmann, S. Walker, D. Wallace, D. Y. Wang, S. Waserman, T. Werfel, M. Westman, M. Wickman, D. M. Williams, S. Williams, N. Wilson, J. Wright, P. Wroczynski, P. Yakovliev, B. P. Yawn, P. K. Yiallouros, A. Yorgancioglu, O. M. Yusuf, H. J. Zar, L. Zhang, N. Zhong, M. E. Zernotti, I. Zhanat, M. Zidarn, T. Zuberbier, C. Zubrinich, A. Zurkuhlen

Research output: Contribution to journalArticle

Abstract

Background: Mobile technology may help to better understand the adherence to treatment. MASK-rhinitis (Mobile Airways Sentinel NetworK for allergic rhinitis) is a patient-centred ICT system. A mobile phone app (the Allergy Diary) central to MASK is available in 22 countries. Objectives: To assess the adherence to treatment in allergic rhinitis patients using the Allergy Diary App. Methods: An observational cross-sectional study was carried out on all users who filled in the Allergy Diary from 1 January 2016 to 1 August 2017. Secondary adherence was assessed by using the modified Medication Possession Ratio (MPR) and the Proportion of days covered (PDC) approach. Results: A total of 12 143 users were registered. A total of 6 949 users reported at least one VAS data recording. Among them, 1 887 users reported ≥7 VAS data. About 1 195 subjects were included in the analysis of adherence. One hundred and thirty-six (11.28%) users were adherent (MPR ≥70% and PDC ≤1.25), 51 (4.23%) were partly adherent (MPR ≥70% and PDC = 1.50) and 176 (14.60%) were switchers. On the other hand, 832 (69.05%) users were non-adherent to medications (MPR <70%). Of those, the largest group was non-adherent to medications and the time interval was increased in 442 (36.68%) users. Conclusion and clinical relevance: Adherence to treatment is low. The relative efficacy of continuous vs on-demand treatment for allergic rhinitis symptoms is still a matter of debate. This study shows an approach for measuring retrospective adherence based on a mobile app. This also represents a novel approach for analysing medication-taking behaviour in a real-world setting.

Original languageEnglish
Pages (from-to)442-460
JournalClinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Volume49
Issue number4
DOIs
Publication statusPublished - Apr 2019

Keywords

  • adherence
  • mHealth
  • mobile technology
  • observational study
  • rhinitis
  • treatment

Cite this

Menditto, Enrica ; Costa, Elisio ; Midao, Luis ; Bosnic-Anticevich, Sinthia ; Novellino, Ettore ; Bialek, Slawomir ; Briedis, Vitalis ; Mair, Alpana ; Rajabian-Soderlund, Rojin ; Arnavielhe, Sylvie ; Bedbrook, Anna ; Czarlewski, Wienczyslawa ; Annesi-Maesano, Isabella ; Anto, Josep M. ; Devillier, Philippe ; De Vries, Govert ; Keil, Thomas ; Sheikh, Aziz ; Orlando, Valentina ; Larenas-Linnemann, Desiree ; Cecchi, Lorenzo ; De Feo, Giulia ; Illario, M. ; Stellato, Cristiana ; Fonseca, Joao ; Malva, Joao ; Morais-Almeida, Mario ; Pereira, Ana Maria ; Todo-Bom, Ana Maria ; Kvedariene, Violeta ; Valiulis, Arunas ; Bergmann, Karl Christian ; Klimek, Ludger ; Moesges, Ralph ; Pfaar, Oliver ; Zuberbier, Torsten ; Cardona, Vicky ; Mullol, Joaquim ; Papadopoulos, Nikos G. ; Prokopakis, Emmanuel P. ; Bewick, Mike ; Ryan, Dermot ; Roller-Wirnsberger, Regina E. ; Tomazic, Peter Valentin ; Cruz, Alvaro A. ; Kuna, Piotr ; Samolinski, Boleslaw ; Fokkens, Wytske J. ; Reitsma, Sietze ; Bosse, Isabelle ; Fontaine, Jean-Francois ; Laune, Daniel ; Haahtela, Tari ; Toppila-Salmi, Sanna ; Bachert, Claus ; Hellings, Peter W. ; Melen, Erik ; Wickman, Magnus ; Bindslev-Jensen, Carsten ; Eller, Esben ; O'Hehir, Robyn E. ; Cingi, Cemal ; Gemicioglu, Bilun ; Kalayci, Omer ; Ivancevich, Juan Carlos ; Bousquet, Jean ; Bousquet, J. ; Hellings, P. W. ; Aberer, W. ; Agache, I. ; Akdis, C. A. ; Akdis, M. ; Aliberti, M. R. ; Almeida, R. ; Amat, F. ; Angles, R. ; Annesi-Maesano, I. ; Ansotegui, I. J. ; Anto, J. M. ; Arnavielle, S. ; Asayag, E. ; Asarnoj, A. ; Arshad, H. ; Avolio, F. ; Bacci, E. ; Bachert, C. ; Baiar-Dini, I. ; Barbara, C. ; Barbagallo, M. ; Baroni, I. ; Barreto, B. A. ; Basagana, X. ; Bateman, E. D. ; Bedolla-Barajas, M. ; Bedbrook, A. ; Bewick, M. ; Beghe, B. ; Bel, E. H. ; Bergmann, K. C. ; Bennoor, K. S. ; Benson, M. ; Bertorello, L. ; Bialoszewski, A. Z. ; Bieber, T. ; Bialek, S. ; Bindslev-Jensen, C. ; Bjermer, L. ; Blain, H. ; Blasi, F. ; Blua, A. ; Marciniak, M. Bochenska ; Bogus-Buczynska, I. ; Boner, A. L. ; Bonini, M. ; Bonini, S. ; Bosnic-Anticevich, C. S. ; Bosse, I. ; Bouchard, J. ; Boulet, L. P. ; Bourret, R. ; Bousquet, Pj ; Braido, F. ; Briedis, V. ; Brightling, C. E. ; Brozek, J. ; Bucca, C. ; Buhl, R. ; Buonaiuto, R. ; Panaitescu, C. ; Cabanas, M. T. Burguete ; Burte, E. ; Bush, A. ; Caballero-Fonseca, F. ; Caillaud, D. ; Caimmi, D. ; Calderon, M. A. ; Camargos, P. A. M. ; Camuzat, T. ; Canfora, G. ; Canonica, G. W. ; Cardona, V. ; Carlsen, K. H. ; Carreiro-Martins, P. ; Carriazo, A. M. ; Carr, W. ; Cartier, C. ; Casale, T. ; Castellano, G. ; Cecchi, L. ; Cepeda, A. M. ; Chavannes, N. H. ; Chen, Y. ; Chiron, R. ; Chivato, T. ; Chkhartishvili, E. ; Chuchalin, A. G. ; Chung, K. F. ; Ciaravolo, M. M. ; Ciceran, A. ; Cingi, C. ; Ciprandi, G. ; Coehlo, A. C. Carvalho ; Colas, L. ; Colgan, E. ; Coll, J. ; Conforti, D. ; De Sousa, J. Correia ; Cortes-Grimaldo, R. M. ; Corti, F. ; Costa, E. ; Mc Costa-Dominguez ; Al Courbis, F. ; Cox, L. ; Crescenzo, M. ; Cruz, A. A. ; Custovic, A. ; Czarlewski, W. ; Dahlen, S. E. ; D'Amato ; Dario, C. ; da Silva, J. ; Dauvilliers, Y. ; Darsow, U. ; De Blay, F. ; De Carlo, G. ; Dedeu, T. ; Emerson, M. De Fatima ; De Feo, G. ; De Vries, G. ; De Martino, B. ; Rubina, N. P. Motta ; Deleanu, D. ; Demoly, P. ; Denburg, Ja ; Devillier, P. ; Ercolano, S. Di Capua ; Di Carluccio, N. ; Didier, A. ; Dokic, D. ; Dominguez-Silva, M. G. ; Douagui, H. ; Dray, G. ; Dubakiene, R. ; Durham, S. R. ; Du Toit, G. ; Dykewicz, M. S. ; El-Gamal, Y. ; Eklund, P. ; Eller, E. ; Emuzyte, R. ; Farrell, J. ; Farsi, A. ; De Mello, J. Ferreira, Jr. ; Ferrero, J. ; Fink-Wagner, A. ; Fiocchi, A. ; Fok-Kens, W. J. ; Fonseca, Ja ; Fontaine, J. F. ; Forti, S. ; Fuentes-Perez, J. M. ; Galvez-Romero, J. L. ; Gamkrelidze, A. ; Garcia-Aymerich, J. ; Garcia-Cobas, C. Y. ; Garcia-Cruz, M. H. ; Gemicioglu, B. ; Genova, S. ; Christoff, G. ; Gereda, J. E. ; Van Wijk, R. Gerth ; Gomez, R. M. ; Gomez-Vera, J. ; Diaz, S. Gonzalez ; Gotua, M. ; Grisle, I. ; Guidacci, M. ; Guldemond, Na ; Gutter, Z. ; Guzman, Ma ; Haahtela, T. ; Hajjam, J. ; Hernandez, L. ; Houri-Hane, JO'B ; Huerta-Villalobos, Y. R. ; Humbert, M. ; Iaccarino, G. ; Illario, M. ; Ispayeva, Z. ; Ivancevich, J. C. ; Jares, Ej ; Jassem, E. ; Johnston, S. L. ; Joos, G. ; Jung, K. S. ; Just, J. ; Jutel, M. ; Kaidashev, I. ; Kalayci, O. ; Kalyoncu, A. F. ; Karjalainen, J. ; Kardas, P. ; Keil, T. ; Keith, P. K. ; Khaitov, M. ; Khaltaev, N. ; Kleine-Tebbe, J. ; Klimek, L. ; Kowalski, M. L. ; Kuitunen, M. ; Kull, I. ; Kuna, P. ; Kupczyk, M. ; Kvedariene, V. ; Krzych-Falta, E. ; Lacwik, P. ; Larenas-Linnemann, D. ; Laune, D. ; Lauri, D. ; Lavrut, J. ; Le, L. T. T. ; Lessa, M. ; Levato, G. ; Li, J. ; Lieberman, P. ; Liplec, A. ; Lipworth, B. ; Carlsen, K. C. Lodrup ; Louis, R. ; Lourenco, O. ; Luna-Pech, J. A. ; Magnan, A. ; Mahboub, B. ; Maier, D. ; Mair, A. ; Majer, I. ; Malva, J. ; Mandajieva, E. ; Manning, P. ; Keenoy, E. De Manuel ; Marshall, G. D. ; Masjedi, M. R. ; Maspero, J. F. ; Mathieu-Dupas, E. ; Campos, J. J. Matta ; Al Matos ; Maurer, M. ; Mavale-Manuel, S. ; Mayora, O. ; Medina-Avalos, M. A. ; Melen, E. ; Melo-Gomes, E. ; Meltzer, Eo ; Menditto, E. ; Mercier, J. ; Miculinic, N. ; Mihaltan, F. ; Milenkovic, B. ; Moda, G. ; Mogica-Martinez, M. D. ; Mohammad, Y. ; Momas, I. ; Monte-Fort, S. ; Monti, R. ; Bogado, D. Mora ; Morais-Almeida, M. ; Morato-Castro ; Mosges, R. ; Mota-Pinto, A. ; Santo, P. Moura ; Mullol, J. ; Munter, L. ; Muraro, A. ; Murray, R. ; Naclerio, R. ; Nadif, R. ; Nalin, M. ; Napoli, L. ; Namazova-Baranova, L. ; Neffen, H. ; Niedeberger, V. ; Nekam, K. ; Neou, A. ; Nieto, A. ; Nogueira-Silva, L. ; Nogues, M. ; Novellino, E. ; Nyembue, Td ; O'Hehir, Re ; Odzhakova, C. ; Ohta, K. ; Okamoto, Y. ; Okubo, K. ; Onorato, G. L. ; Cisneros, M. Ortega ; Ouedraogo, S. ; Pali-Scholl, I. ; Palkonen, S. ; Panzner, P. ; Papadopoulos, N. G. ; Park, H. S. ; Papi, A. ; Passalacqua, G. ; Paulino, E. ; Pawankar, R. ; Pedersen, S. ; Pepin, J. L. ; Pereira, A. M. ; Persico, M. ; Pfaar, O. ; Phillips, J. ; Picard, R. ; Pigearias, B. ; Pin, I. ; Pitsios, C. ; Plavec, D. ; Pohl, W. ; Popov, T. A. ; Portejoie, F. ; Potter, P. ; Pozzi, A. C. ; Price, D. ; Prokopakis, E. P. ; Puy, R. ; Pugin, B. ; Ross, R. E. Pulido ; Przemecka, M. ; Rabe, K. F. ; Raciborski, F. ; Raja-Bian-Soderlund, R. ; Reitsma, S. ; Ribeirinho, I. ; Rimmer, J. ; Riv-Ero-Yeverino, D. ; Rizzo, J. A. ; Rizzo, M. C. ; Robalo-Cordeiro, C. ; Rodenas, F. ; Rodo, X. ; Gonzalez, M. Rodriguez ; Rodriguez-Manas, L. ; Rolland, C. ; Valle, S. Rodrigues ; Rodriguez, M. Roman ; Romano, A. ; Rodriguez-Zagal, E. ; Rolla, G. ; Roller-Wirnsberger, R. E. ; Romano, M. ; Rosado-Pinto, J. ; Rosario, N. ; Rottem, M. ; Ryan, D. ; Sagara, H. ; Salimaki, J. ; Samolinski, B. ; Sanchez-Borges, M. ; Sastre-Dominguez, J. ; Scadding, G. K. ; Schunemann, H. J. ; Scichilone, N. ; Schmid-Grendelmeier, P. ; Serpa, F. S. ; Shamai, S. ; Sheikh, A. ; Sierra, M. ; Simons, F. E. R. ; Sir-Oux, V. ; Sisul, J. C. ; Skrindo, I. ; Sole, D. ; Somekh, D. ; Sonder-Mann, M. ; Sooronbaev, T. ; Sova, M. ; Sorensen, M. ; Sorlini, M. ; Spranger, O. ; Stellato, C. ; Stelmach, R. ; Stukas, R. ; Sunyer, J. ; Strozek, J. ; Szylling, A. ; Tebyrica, Jn ; Thibaudon, M. ; To, T. ; Todo-Bom, A. ; Tomazic, P. V. ; Toppila-Salmi, S. ; Trama, U. ; Triggiani, M. ; Ulrik, C. Suppli ; Urrutia-Pereira, M. ; Valenta, R. ; Valero, A. ; Valiulis, A. ; Valovirta, E. ; Van Eerd, M. ; Van Ganse, E. ; Van Hague, M. ; Vandenplas, O. ; Ventura, M. T. ; Vezzani, G. ; Vasankari, T. ; Vatrella, A. ; Verissimo, M. T. ; Viart, F. ; Viegi, G. ; Vicheva, D. ; Vontetsianos, T. ; Wagenmann, M. ; Walker, S. ; Wallace, D. ; Wang, D. Y. ; Waserman, S. ; Werfel, T. ; Westman, M. ; Wickman, M. ; Williams, D. M. ; Williams, S. ; Wilson, N. ; Wright, J. ; Wroczynski, P. ; Yakovliev, P. ; Yawn, B. P. ; Yiallouros, P. K. ; Yorgancioglu, A. ; Yusuf, O. M. ; Zar, H. J. ; Zhang, L. ; Zhong, N. ; Zernotti, M. E. ; Zhanat, I. ; Zidarn, M. ; Zuberbier, T. ; Zubrinich, C. ; Zurkuhlen, A. / Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study. In: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2019 ; Vol. 49, No. 4. pp. 442-460.
@article{6c1e60ed12214525acfa27325bcec504,
title = "Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study",
abstract = "Background: Mobile technology may help to better understand the adherence to treatment. MASK-rhinitis (Mobile Airways Sentinel NetworK for allergic rhinitis) is a patient-centred ICT system. A mobile phone app (the Allergy Diary) central to MASK is available in 22 countries. Objectives: To assess the adherence to treatment in allergic rhinitis patients using the Allergy Diary App. Methods: An observational cross-sectional study was carried out on all users who filled in the Allergy Diary from 1 January 2016 to 1 August 2017. Secondary adherence was assessed by using the modified Medication Possession Ratio (MPR) and the Proportion of days covered (PDC) approach. Results: A total of 12 143 users were registered. A total of 6 949 users reported at least one VAS data recording. Among them, 1 887 users reported ≥7 VAS data. About 1 195 subjects were included in the analysis of adherence. One hundred and thirty-six (11.28{\%}) users were adherent (MPR ≥70{\%} and PDC ≤1.25), 51 (4.23{\%}) were partly adherent (MPR ≥70{\%} and PDC = 1.50) and 176 (14.60{\%}) were switchers. On the other hand, 832 (69.05{\%}) users were non-adherent to medications (MPR <70{\%}). Of those, the largest group was non-adherent to medications and the time interval was increased in 442 (36.68{\%}) users. Conclusion and clinical relevance: Adherence to treatment is low. The relative efficacy of continuous vs on-demand treatment for allergic rhinitis symptoms is still a matter of debate. This study shows an approach for measuring retrospective adherence based on a mobile app. This also represents a novel approach for analysing medication-taking behaviour in a real-world setting.",
keywords = "adherence, mHealth, mobile technology, observational study, rhinitis, treatment",
author = "Enrica Menditto and Elisio Costa and Luis Midao and Sinthia Bosnic-Anticevich and Ettore Novellino and Slawomir Bialek and Vitalis Briedis and Alpana Mair and Rojin Rajabian-Soderlund and Sylvie Arnavielhe and Anna Bedbrook and Wienczyslawa Czarlewski and Isabella Annesi-Maesano and Anto, {Josep M.} and Philippe Devillier and {De Vries}, Govert and Thomas Keil and Aziz Sheikh and Valentina Orlando and Desiree Larenas-Linnemann and Lorenzo Cecchi and {De Feo}, Giulia and M. Illario and Cristiana Stellato and Joao Fonseca and Joao Malva and Mario Morais-Almeida and Pereira, {Ana Maria} and Todo-Bom, {Ana Maria} and Violeta Kvedariene and Arunas Valiulis and Bergmann, {Karl Christian} and Ludger Klimek and Ralph Moesges and Oliver Pfaar and Torsten Zuberbier and Vicky Cardona and Joaquim Mullol and Papadopoulos, {Nikos G.} and Prokopakis, {Emmanuel P.} and Mike Bewick and Dermot Ryan and Roller-Wirnsberger, {Regina E.} and Tomazic, {Peter Valentin} and Cruz, {Alvaro A.} and Piotr Kuna and Boleslaw Samolinski and Fokkens, {Wytske J.} and Sietze Reitsma and Isabelle Bosse and Jean-Francois Fontaine and Daniel Laune and Tari Haahtela and Sanna Toppila-Salmi and Claus Bachert and Hellings, {Peter W.} and Erik Melen and Magnus Wickman and Carsten Bindslev-Jensen and Esben Eller and O'Hehir, {Robyn E.} and Cemal Cingi and Bilun Gemicioglu and Omer Kalayci and Ivancevich, {Juan Carlos} and Jean Bousquet and J. Bousquet and Hellings, {P. W.} and W. Aberer and I. Agache and Akdis, {C. A.} and M. Akdis and Aliberti, {M. R.} and R. Almeida and F. Amat and R. Angles and I. Annesi-Maesano and Ansotegui, {I. J.} and Anto, {J. M.} and S. Arnavielle and E. Asayag and A. Asarnoj and H. Arshad and F. Avolio and E. Bacci and C. Bachert and I. Baiar-Dini and C. Barbara and M. Barbagallo and I. Baroni and Barreto, {B. A.} and X. Basagana and Bateman, {E. D.} and M. Bedolla-Barajas and A. Bedbrook and M. Bewick and B. Beghe and Bel, {E. H.} and Bergmann, {K. C.} and Bennoor, {K. S.} and M. Benson and L. Bertorello and Bialoszewski, {A. Z.} and T. Bieber and S. Bialek and C. Bindslev-Jensen and L. Bjermer and H. Blain and F. Blasi and A. Blua and Marciniak, {M. Bochenska} and I. Bogus-Buczynska and Boner, {A. L.} and M. Bonini and S. Bonini and Bosnic-Anticevich, {C. S.} and I. Bosse and J. Bouchard and Boulet, {L. P.} and R. Bourret and Pj Bousquet and F. Braido and V. Briedis and Brightling, {C. E.} and J. Brozek and C. Bucca and R. Buhl and R. Buonaiuto and C. Panaitescu and Cabanas, {M. T. Burguete} and E. Burte and A. Bush and F. Caballero-Fonseca and D. Caillaud and D. Caimmi and Calderon, {M. A.} and Camargos, {P. A. M.} and T. Camuzat and G. Canfora and Canonica, {G. W.} and V. Cardona and Carlsen, {K. H.} and P. Carreiro-Martins and Carriazo, {A. M.} and W. Carr and C. Cartier and T. Casale and G. Castellano and L. Cecchi and Cepeda, {A. M.} and Chavannes, {N. H.} and Y. Chen and R. Chiron and T. Chivato and E. Chkhartishvili and Chuchalin, {A. G.} and Chung, {K. F.} and Ciaravolo, {M. M.} and A. Ciceran and C. Cingi and G. Ciprandi and Coehlo, {A. C. Carvalho} and L. Colas and E. Colgan and J. Coll and D. Conforti and {De Sousa}, {J. Correia} and Cortes-Grimaldo, {R. M.} and F. Corti and E. Costa and {Mc Costa-Dominguez} and {Al Courbis}, F. and L. Cox and M. Crescenzo and Cruz, {A. A.} and A. Custovic and W. Czarlewski and Dahlen, {S. E.} and D'Amato and C. Dario and {da Silva}, J. and Y. Dauvilliers and U. Darsow and {De Blay}, F. and {De Carlo}, G. and T. Dedeu and Emerson, {M. De Fatima} and {De Feo}, G. and {De Vries}, G. and {De Martino}, B. and Rubina, {N. P. Motta} and D. Deleanu and P. Demoly and Ja Denburg and P. Devillier and Ercolano, {S. Di Capua} and {Di Carluccio}, N. and A. Didier and D. Dokic and Dominguez-Silva, {M. G.} and H. Douagui and G. Dray and R. Dubakiene and Durham, {S. R.} and {Du Toit}, G. and Dykewicz, {M. S.} and Y. El-Gamal and P. Eklund and E. Eller and R. Emuzyte and J. Farrell and A. Farsi and {De Mello}, {J. Ferreira, Jr.} and J. Ferrero and A. Fink-Wagner and A. Fiocchi and Fok-Kens, {W. J.} and Ja Fonseca and Fontaine, {J. F.} and S. Forti and Fuentes-Perez, {J. M.} and Galvez-Romero, {J. L.} and A. Gamkrelidze and J. Garcia-Aymerich and Garcia-Cobas, {C. Y.} and Garcia-Cruz, {M. H.} and B. Gemicioglu and S. Genova and G. Christoff and Gereda, {J. E.} and {Van Wijk}, {R. Gerth} and Gomez, {R. M.} and J. Gomez-Vera and Diaz, {S. Gonzalez} and M. Gotua and I. Grisle and M. Guidacci and Na Guldemond and Z. Gutter and Ma Guzman and T. Haahtela and J. Hajjam and L. Hernandez and JO'B Houri-Hane and Huerta-Villalobos, {Y. R.} and M. Humbert and G. Iaccarino and M. Illario and Z. Ispayeva and Ivancevich, {J. C.} and Ej Jares and E. Jassem and Johnston, {S. L.} and G. Joos and Jung, {K. S.} and J. Just and M. Jutel and I. Kaidashev and O. Kalayci and Kalyoncu, {A. F.} and J. Karjalainen and P. Kardas and T. Keil and Keith, {P. K.} and M. Khaitov and N. Khaltaev and J. Kleine-Tebbe and L. Klimek and Kowalski, {M. L.} and M. Kuitunen and I. Kull and P. Kuna and M. Kupczyk and V. Kvedariene and E. Krzych-Falta and P. Lacwik and D. Larenas-Linnemann and D. Laune and D. Lauri and J. Lavrut and Le, {L. T. T.} and M. Lessa and G. Levato and J. Li and P. Lieberman and A. Liplec and B. Lipworth and Carlsen, {K. C. Lodrup} and R. Louis and O. Lourenco and Luna-Pech, {J. A.} and A. Magnan and B. Mahboub and D. Maier and A. Mair and I. Majer and J. Malva and E. Mandajieva and P. Manning and Keenoy, {E. De Manuel} and Marshall, {G. D.} and Masjedi, {M. R.} and Maspero, {J. F.} and E. Mathieu-Dupas and Campos, {J. J. Matta} and {Al Matos} and M. Maurer and S. Mavale-Manuel and O. Mayora and Medina-Avalos, {M. A.} and E. Melen and E. Melo-Gomes and Eo Meltzer and E. Menditto and J. Mercier and N. Miculinic and F. Mihaltan and B. Milenkovic and G. Moda and Mogica-Martinez, {M. D.} and Y. Mohammad and I. Momas and S. Monte-Fort and R. Monti and Bogado, {D. Mora} and M. Morais-Almeida and Morato-Castro and R. Mosges and A. Mota-Pinto and Santo, {P. Moura} and J. Mullol and L. Munter and A. Muraro and R. Murray and R. Naclerio and R. Nadif and M. Nalin and L. Napoli and L. Namazova-Baranova and H. Neffen and V. Niedeberger and K. Nekam and A. Neou and A. Nieto and L. Nogueira-Silva and M. Nogues and E. Novellino and Td Nyembue and Re O'Hehir and C. Odzhakova and K. Ohta and Y. Okamoto and K. Okubo and Onorato, {G. L.} and Cisneros, {M. Ortega} and S. Ouedraogo and I. Pali-Scholl and S. Palkonen and P. Panzner and Papadopoulos, {N. G.} and Park, {H. S.} and A. Papi and G. Passalacqua and E. Paulino and R. Pawankar and S. Pedersen and Pepin, {J. L.} and Pereira, {A. M.} and M. Persico and O. Pfaar and J. Phillips and R. Picard and B. Pigearias and I. Pin and C. Pitsios and D. Plavec and W. Pohl and Popov, {T. A.} and F. Portejoie and P. Potter and Pozzi, {A. C.} and D. Price and Prokopakis, {E. P.} and R. Puy and B. Pugin and Ross, {R. E. Pulido} and M. Przemecka and Rabe, {K. F.} and F. Raciborski and R. Raja-Bian-Soderlund and S. Reitsma and I. Ribeirinho and J. Rimmer and D. Riv-Ero-Yeverino and Rizzo, {J. A.} and Rizzo, {M. C.} and C. Robalo-Cordeiro and F. Rodenas and X. Rodo and Gonzalez, {M. Rodriguez} and L. Rodriguez-Manas and C. Rolland and Valle, {S. Rodrigues} and Rodriguez, {M. Roman} and A. Romano and E. Rodriguez-Zagal and G. Rolla and Roller-Wirnsberger, {R. E.} and M. Romano and J. Rosado-Pinto and N. Rosario and M. Rottem and D. Ryan and H. Sagara and J. Salimaki and B. Samolinski and M. Sanchez-Borges and J. Sastre-Dominguez and Scadding, {G. K.} and Schunemann, {H. J.} and N. Scichilone and P. Schmid-Grendelmeier and Serpa, {F. S.} and S. Shamai and A. Sheikh and M. Sierra and Simons, {F. E. R.} and V. Sir-Oux and Sisul, {J. C.} and I. Skrindo and D. Sole and D. Somekh and M. Sonder-Mann and T. Sooronbaev and M. Sova and M. Sorensen and M. Sorlini and O. Spranger and C. Stellato and R. Stelmach and R. Stukas and J. Sunyer and J. Strozek and A. Szylling and Jn Tebyrica and M. Thibaudon and T. To and A. Todo-Bom and Tomazic, {P. V.} and S. Toppila-Salmi and U. Trama and M. Triggiani and Ulrik, {C. Suppli} and M. Urrutia-Pereira and R. Valenta and A. Valero and A. Valiulis and E. Valovirta and {Van Eerd}, M. and {Van Ganse}, E. and {Van Hague}, M. and O. Vandenplas and Ventura, {M. T.} and G. Vezzani and T. Vasankari and A. Vatrella and Verissimo, {M. T.} and F. Viart and G. Viegi and D. Vicheva and T. Vontetsianos and M. Wagenmann and S. Walker and D. Wallace and Wang, {D. Y.} and S. Waserman and T. Werfel and M. Westman and M. Wickman and Williams, {D. M.} and S. Williams and N. Wilson and J. Wright and P. Wroczynski and P. Yakovliev and Yawn, {B. P.} and Yiallouros, {P. K.} and A. Yorgancioglu and Yusuf, {O. M.} and Zar, {H. J.} and L. Zhang and N. Zhong and Zernotti, {M. E.} and I. Zhanat and M. Zidarn and T. Zuberbier and C. Zubrinich and A. Zurkuhlen",
year = "2019",
month = "4",
doi = "10.1111/cea.13333",
language = "English",
volume = "49",
pages = "442--460",
journal = "Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology",
issn = "0954-7894",
publisher = "Wiley",
number = "4",

}

Menditto, E, Costa, E, Midao, L, Bosnic-Anticevich, S, Novellino, E, Bialek, S, Briedis, V, Mair, A, Rajabian-Soderlund, R, Arnavielhe, S, Bedbrook, A, Czarlewski, W, Annesi-Maesano, I, Anto, JM, Devillier, P, De Vries, G, Keil, T, Sheikh, A, Orlando, V, Larenas-Linnemann, D, Cecchi, L, De Feo, G, Illario, M, Stellato, C, Fonseca, J, Malva, J, Morais-Almeida, M, Pereira, AM, Todo-Bom, AM, Kvedariene, V, Valiulis, A, Bergmann, KC, Klimek, L, Moesges, R, Pfaar, O, Zuberbier, T, Cardona, V, Mullol, J, Papadopoulos, NG, Prokopakis, EP, Bewick, M, Ryan, D, Roller-Wirnsberger, RE, Tomazic, PV, Cruz, AA, Kuna, P, Samolinski, B, Fokkens, WJ, Reitsma, S, Bosse, I, Fontaine, J-F, Laune, D, Haahtela, T, Toppila-Salmi, S, Bachert, C, Hellings, PW, Melen, E, Wickman, M, Bindslev-Jensen, C, Eller, E, O'Hehir, RE, Cingi, C, Gemicioglu, B, Kalayci, O, Ivancevich, JC, Bousquet, J, Bousquet, J, Hellings, PW, Aberer, W, Agache, I, Akdis, CA, Akdis, M, Aliberti, MR, Almeida, R, Amat, F, Angles, R, Annesi-Maesano, I, Ansotegui, IJ, Anto, JM, Arnavielle, S, Asayag, E, Asarnoj, A, Arshad, H, Avolio, F, Bacci, E, Bachert, C, Baiar-Dini, I, Barbara, C, Barbagallo, M, Baroni, I, Barreto, BA, Basagana, X, Bateman, ED, Bedolla-Barajas, M, Bedbrook, A, Bewick, M, Beghe, B, Bel, EH, Bergmann, KC, Bennoor, KS, Benson, M, Bertorello, L, Bialoszewski, AZ, Bieber, T, Bialek, S, Bindslev-Jensen, C, Bjermer, L, Blain, H, Blasi, F, Blua, A, Marciniak, MB, Bogus-Buczynska, I, Boner, AL, Bonini, M, Bonini, S, Bosnic-Anticevich, CS, Bosse, I, Bouchard, J, Boulet, LP, Bourret, R, Bousquet, P, Braido, F, Briedis, V, Brightling, CE, Brozek, J, Bucca, C, Buhl, R, Buonaiuto, R, Panaitescu, C, Cabanas, MTB, Burte, E, Bush, A, Caballero-Fonseca, F, Caillaud, D, Caimmi, D, Calderon, MA, Camargos, PAM, Camuzat, T, Canfora, G, Canonica, GW, Cardona, V, Carlsen, KH, Carreiro-Martins, P, Carriazo, AM, Carr, W, Cartier, C, Casale, T, Castellano, G, Cecchi, L, Cepeda, AM, Chavannes, NH, Chen, Y, Chiron, R, Chivato, T, Chkhartishvili, E, Chuchalin, AG, Chung, KF, Ciaravolo, MM, Ciceran, A, Cingi, C, Ciprandi, G, Coehlo, ACC, Colas, L, Colgan, E, Coll, J, Conforti, D, De Sousa, JC, Cortes-Grimaldo, RM, Corti, F, Costa, E, Mc Costa-Dominguez, Al Courbis, F, Cox, L, Crescenzo, M, Cruz, AA, Custovic, A, Czarlewski, W, Dahlen, SE, D'Amato, Dario, C, da Silva, J, Dauvilliers, Y, Darsow, U, De Blay, F, De Carlo, G, Dedeu, T, Emerson, MDF, De Feo, G, De Vries, G, De Martino, B, Rubina, NPM, Deleanu, D, Demoly, P, Denburg, J, Devillier, P, Ercolano, SDC, Di Carluccio, N, Didier, A, Dokic, D, Dominguez-Silva, MG, Douagui, H, Dray, G, Dubakiene, R, Durham, SR, Du Toit, G, Dykewicz, MS, El-Gamal, Y, Eklund, P, Eller, E, Emuzyte, R, Farrell, J, Farsi, A, De Mello, JFJ, Ferrero, J, Fink-Wagner, A, Fiocchi, A, Fok-Kens, WJ, Fonseca, J, Fontaine, JF, Forti, S, Fuentes-Perez, JM, Galvez-Romero, JL, Gamkrelidze, A, Garcia-Aymerich, J, Garcia-Cobas, CY, Garcia-Cruz, MH, Gemicioglu, B, Genova, S, Christoff, G, Gereda, JE, Van Wijk, RG, Gomez, RM, Gomez-Vera, J, Diaz, SG, Gotua, M, Grisle, I, Guidacci, M, Guldemond, N, Gutter, Z, Guzman, M, Haahtela, T, Hajjam, J, Hernandez, L, Houri-Hane, JOB, Huerta-Villalobos, YR, Humbert, M, Iaccarino, G, Illario, M, Ispayeva, Z, Ivancevich, JC, Jares, E, Jassem, E, Johnston, SL, Joos, G, Jung, KS, Just, J, Jutel, M, Kaidashev, I, Kalayci, O, Kalyoncu, AF, Karjalainen, J, Kardas, P, Keil, T, Keith, PK, Khaitov, M, Khaltaev, N, Kleine-Tebbe, J, Klimek, L, Kowalski, ML, Kuitunen, M, Kull, I, Kuna, P, Kupczyk, M, Kvedariene, V, Krzych-Falta, E, Lacwik, P, Larenas-Linnemann, D, Laune, D, Lauri, D, Lavrut, J, Le, LTT, Lessa, M, Levato, G, Li, J, Lieberman, P, Liplec, A, Lipworth, B, Carlsen, KCL, Louis, R, Lourenco, O, Luna-Pech, JA, Magnan, A, Mahboub, B, Maier, D, Mair, A, Majer, I, Malva, J, Mandajieva, E, Manning, P, Keenoy, EDM, Marshall, GD, Masjedi, MR, Maspero, JF, Mathieu-Dupas, E, Campos, JJM, Al Matos, Maurer, M, Mavale-Manuel, S, Mayora, O, Medina-Avalos, MA, Melen, E, Melo-Gomes, E, Meltzer, E, Menditto, E, Mercier, J, Miculinic, N, Mihaltan, F, Milenkovic, B, Moda, G, Mogica-Martinez, MD, Mohammad, Y, Momas, I, Monte-Fort, S, Monti, R, Bogado, DM, Morais-Almeida, M, Morato-Castro, Mosges, R, Mota-Pinto, A, Santo, PM, Mullol, J, Munter, L, Muraro, A, Murray, R, Naclerio, R, Nadif, R, Nalin, M, Napoli, L, Namazova-Baranova, L, Neffen, H, Niedeberger, V, Nekam, K, Neou, A, Nieto, A, Nogueira-Silva, L, Nogues, M, Novellino, E, Nyembue, T, O'Hehir, R, Odzhakova, C, Ohta, K, Okamoto, Y, Okubo, K, Onorato, GL, Cisneros, MO, Ouedraogo, S, Pali-Scholl, I, Palkonen, S, Panzner, P, Papadopoulos, NG, Park, HS, Papi, A, Passalacqua, G, Paulino, E, Pawankar, R, Pedersen, S, Pepin, JL, Pereira, AM, Persico, M, Pfaar, O, Phillips, J, Picard, R, Pigearias, B, Pin, I, Pitsios, C, Plavec, D, Pohl, W, Popov, TA, Portejoie, F, Potter, P, Pozzi, AC, Price, D, Prokopakis, EP, Puy, R, Pugin, B, Ross, REP, Przemecka, M, Rabe, KF, Raciborski, F, Raja-Bian-Soderlund, R, Reitsma, S, Ribeirinho, I, Rimmer, J, Riv-Ero-Yeverino, D, Rizzo, JA, Rizzo, MC, Robalo-Cordeiro, C, Rodenas, F, Rodo, X, Gonzalez, MR, Rodriguez-Manas, L, Rolland, C, Valle, SR, Rodriguez, MR, Romano, A, Rodriguez-Zagal, E, Rolla, G, Roller-Wirnsberger, RE, Romano, M, Rosado-Pinto, J, Rosario, N, Rottem, M, Ryan, D, Sagara, H, Salimaki, J, Samolinski, B, Sanchez-Borges, M, Sastre-Dominguez, J, Scadding, GK, Schunemann, HJ, Scichilone, N, Schmid-Grendelmeier, P, Serpa, FS, Shamai, S, Sheikh, A, Sierra, M, Simons, FER, Sir-Oux, V, Sisul, JC, Skrindo, I, Sole, D, Somekh, D, Sonder-Mann, M, Sooronbaev, T, Sova, M, Sorensen, M, Sorlini, M, Spranger, O, Stellato, C, Stelmach, R, Stukas, R, Sunyer, J, Strozek, J, Szylling, A, Tebyrica, J, Thibaudon, M, To, T, Todo-Bom, A, Tomazic, PV, Toppila-Salmi, S, Trama, U, Triggiani, M, Ulrik, CS, Urrutia-Pereira, M, Valenta, R, Valero, A, Valiulis, A, Valovirta, E, Van Eerd, M, Van Ganse, E, Van Hague, M, Vandenplas, O, Ventura, MT, Vezzani, G, Vasankari, T, Vatrella, A, Verissimo, MT, Viart, F, Viegi, G, Vicheva, D, Vontetsianos, T, Wagenmann, M, Walker, S, Wallace, D, Wang, DY, Waserman, S, Werfel, T, Westman, M, Wickman, M, Williams, DM, Williams, S, Wilson, N, Wright, J, Wroczynski, P, Yakovliev, P, Yawn, BP, Yiallouros, PK, Yorgancioglu, A, Yusuf, OM, Zar, HJ, Zhang, L, Zhong, N, Zernotti, ME, Zhanat, I, Zidarn, M, Zuberbier, T, Zubrinich, C & Zurkuhlen, A 2019, 'Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study' Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, vol. 49, no. 4, pp. 442-460. https://doi.org/10.1111/cea.13333

Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study. / Menditto, Enrica; Costa, Elisio; Midao, Luis; Bosnic-Anticevich, Sinthia; Novellino, Ettore; Bialek, Slawomir; Briedis, Vitalis; Mair, Alpana; Rajabian-Soderlund, Rojin; Arnavielhe, Sylvie; Bedbrook, Anna; Czarlewski, Wienczyslawa; Annesi-Maesano, Isabella; Anto, Josep M.; Devillier, Philippe; De Vries, Govert; Keil, Thomas; Sheikh, Aziz; Orlando, Valentina; Larenas-Linnemann, Desiree; Cecchi, Lorenzo; De Feo, Giulia; Illario, M.; Stellato, Cristiana; Fonseca, Joao; Malva, Joao; Morais-Almeida, Mario; Pereira, Ana Maria; Todo-Bom, Ana Maria; Kvedariene, Violeta; Valiulis, Arunas; Bergmann, Karl Christian; Klimek, Ludger; Moesges, Ralph; Pfaar, Oliver; Zuberbier, Torsten; Cardona, Vicky; Mullol, Joaquim; Papadopoulos, Nikos G.; Prokopakis, Emmanuel P.; Bewick, Mike; Ryan, Dermot; Roller-Wirnsberger, Regina E.; Tomazic, Peter Valentin; Cruz, Alvaro A.; Kuna, Piotr; Samolinski, Boleslaw; Fokkens, Wytske J.; Reitsma, Sietze; Bosse, Isabelle; Fontaine, Jean-Francois; Laune, Daniel; Haahtela, Tari; Toppila-Salmi, Sanna; Bachert, Claus; Hellings, Peter W.; Melen, Erik; Wickman, Magnus; Bindslev-Jensen, Carsten; Eller, Esben; O'Hehir, Robyn E.; Cingi, Cemal; Gemicioglu, Bilun; Kalayci, Omer; Ivancevich, Juan Carlos; Bousquet, Jean; Bousquet, J.; Hellings, P. W.; Aberer, W.; Agache, I.; Akdis, C. A.; Akdis, M.; Aliberti, M. R.; Almeida, R.; Amat, F.; Angles, R.; Annesi-Maesano, I.; Ansotegui, I. J.; Anto, J. M.; Arnavielle, S.; Asayag, E.; Asarnoj, A.; Arshad, H.; Avolio, F.; Bacci, E.; Bachert, C.; Baiar-Dini, I.; Barbara, C.; Barbagallo, M.; Baroni, I.; Barreto, B. A.; Basagana, X.; Bateman, E. D.; Bedolla-Barajas, M.; Bedbrook, A.; Bewick, M.; Beghe, B.; Bel, E. H.; Bergmann, K. C.; Bennoor, K. S.; Benson, M.; Bertorello, L.; Bialoszewski, A. Z.; Bieber, T.; Bialek, S.; Bindslev-Jensen, C.; Bjermer, L.; Blain, H.; Blasi, F.; Blua, A.; Marciniak, M. Bochenska; Bogus-Buczynska, I.; Boner, A. L.; Bonini, M.; Bonini, S.; Bosnic-Anticevich, C. S.; Bosse, I.; Bouchard, J.; Boulet, L. P.; Bourret, R.; Bousquet, Pj; Braido, F.; Briedis, V.; Brightling, C. E.; Brozek, J.; Bucca, C.; Buhl, R.; Buonaiuto, R.; Panaitescu, C.; Cabanas, M. T. Burguete; Burte, E.; Bush, A.; Caballero-Fonseca, F.; Caillaud, D.; Caimmi, D.; Calderon, M. A.; Camargos, P. A. M.; Camuzat, T.; Canfora, G.; Canonica, G. W.; Cardona, V.; Carlsen, K. H.; Carreiro-Martins, P.; Carriazo, A. M.; Carr, W.; Cartier, C.; Casale, T.; Castellano, G.; Cecchi, L.; Cepeda, A. M.; Chavannes, N. H.; Chen, Y.; Chiron, R.; Chivato, T.; Chkhartishvili, E.; Chuchalin, A. G.; Chung, K. F.; Ciaravolo, M. M.; Ciceran, A.; Cingi, C.; Ciprandi, G.; Coehlo, A. C. Carvalho; Colas, L.; Colgan, E.; Coll, J.; Conforti, D.; De Sousa, J. Correia; Cortes-Grimaldo, R. M.; Corti, F.; Costa, E.; Mc Costa-Dominguez; Al Courbis, F.; Cox, L.; Crescenzo, M.; Cruz, A. A.; Custovic, A.; Czarlewski, W.; Dahlen, S. E.; D'Amato; Dario, C.; da Silva, J.; Dauvilliers, Y.; Darsow, U.; De Blay, F.; De Carlo, G.; Dedeu, T.; Emerson, M. De Fatima; De Feo, G.; De Vries, G.; De Martino, B.; Rubina, N. P. Motta; Deleanu, D.; Demoly, P.; Denburg, Ja; Devillier, P.; Ercolano, S. Di Capua; Di Carluccio, N.; Didier, A.; Dokic, D.; Dominguez-Silva, M. G.; Douagui, H.; Dray, G.; Dubakiene, R.; Durham, S. R.; Du Toit, G.; Dykewicz, M. S.; El-Gamal, Y.; Eklund, P.; Eller, E.; Emuzyte, R.; Farrell, J.; Farsi, A.; De Mello, J. Ferreira, Jr.; Ferrero, J.; Fink-Wagner, A.; Fiocchi, A.; Fok-Kens, W. J.; Fonseca, Ja; Fontaine, J. F.; Forti, S.; Fuentes-Perez, J. M.; Galvez-Romero, J. L.; Gamkrelidze, A.; Garcia-Aymerich, J.; Garcia-Cobas, C. Y.; Garcia-Cruz, M. H.; Gemicioglu, B.; Genova, S.; Christoff, G.; Gereda, J. E.; Van Wijk, R. Gerth; Gomez, R. M.; Gomez-Vera, J.; Diaz, S. Gonzalez; Gotua, M.; Grisle, I.; Guidacci, M.; Guldemond, Na; Gutter, Z.; Guzman, Ma; Haahtela, T.; Hajjam, J.; Hernandez, L.; Houri-Hane, JO'B; Huerta-Villalobos, Y. R.; Humbert, M.; Iaccarino, G.; Illario, M.; Ispayeva, Z.; Ivancevich, J. C.; Jares, Ej; Jassem, E.; Johnston, S. L.; Joos, G.; Jung, K. S.; Just, J.; Jutel, M.; Kaidashev, I.; Kalayci, O.; Kalyoncu, A. F.; Karjalainen, J.; Kardas, P.; Keil, T.; Keith, P. K.; Khaitov, M.; Khaltaev, N.; Kleine-Tebbe, J.; Klimek, L.; Kowalski, M. L.; Kuitunen, M.; Kull, I.; Kuna, P.; Kupczyk, M.; Kvedariene, V.; Krzych-Falta, E.; Lacwik, P.; Larenas-Linnemann, D.; Laune, D.; Lauri, D.; Lavrut, J.; Le, L. T. T.; Lessa, M.; Levato, G.; Li, J.; Lieberman, P.; Liplec, A.; Lipworth, B.; Carlsen, K. C. Lodrup; Louis, R.; Lourenco, O.; Luna-Pech, J. A.; Magnan, A.; Mahboub, B.; Maier, D.; Mair, A.; Majer, I.; Malva, J.; Mandajieva, E.; Manning, P.; Keenoy, E. De Manuel; Marshall, G. D.; Masjedi, M. R.; Maspero, J. F.; Mathieu-Dupas, E.; Campos, J. J. Matta; Al Matos; Maurer, M.; Mavale-Manuel, S.; Mayora, O.; Medina-Avalos, M. A.; Melen, E.; Melo-Gomes, E.; Meltzer, Eo; Menditto, E.; Mercier, J.; Miculinic, N.; Mihaltan, F.; Milenkovic, B.; Moda, G.; Mogica-Martinez, M. D.; Mohammad, Y.; Momas, I.; Monte-Fort, S.; Monti, R.; Bogado, D. Mora; Morais-Almeida, M.; Morato-Castro; Mosges, R.; Mota-Pinto, A.; Santo, P. Moura; Mullol, J.; Munter, L.; Muraro, A.; Murray, R.; Naclerio, R.; Nadif, R.; Nalin, M.; Napoli, L.; Namazova-Baranova, L.; Neffen, H.; Niedeberger, V.; Nekam, K.; Neou, A.; Nieto, A.; Nogueira-Silva, L.; Nogues, M.; Novellino, E.; Nyembue, Td; O'Hehir, Re; Odzhakova, C.; Ohta, K.; Okamoto, Y.; Okubo, K.; Onorato, G. L.; Cisneros, M. Ortega; Ouedraogo, S.; Pali-Scholl, I.; Palkonen, S.; Panzner, P.; Papadopoulos, N. G.; Park, H. S.; Papi, A.; Passalacqua, G.; Paulino, E.; Pawankar, R.; Pedersen, S.; Pepin, J. L.; Pereira, A. M.; Persico, M.; Pfaar, O.; Phillips, J.; Picard, R.; Pigearias, B.; Pin, I.; Pitsios, C.; Plavec, D.; Pohl, W.; Popov, T. A.; Portejoie, F.; Potter, P.; Pozzi, A. C.; Price, D.; Prokopakis, E. P.; Puy, R.; Pugin, B.; Ross, R. E. Pulido; Przemecka, M.; Rabe, K. F.; Raciborski, F.; Raja-Bian-Soderlund, R.; Reitsma, S.; Ribeirinho, I.; Rimmer, J.; Riv-Ero-Yeverino, D.; Rizzo, J. A.; Rizzo, M. C.; Robalo-Cordeiro, C.; Rodenas, F.; Rodo, X.; Gonzalez, M. Rodriguez; Rodriguez-Manas, L.; Rolland, C.; Valle, S. Rodrigues; Rodriguez, M. Roman; Romano, A.; Rodriguez-Zagal, E.; Rolla, G.; Roller-Wirnsberger, R. E.; Romano, M.; Rosado-Pinto, J.; Rosario, N.; Rottem, M.; Ryan, D.; Sagara, H.; Salimaki, J.; Samolinski, B.; Sanchez-Borges, M.; Sastre-Dominguez, J.; Scadding, G. K.; Schunemann, H. J.; Scichilone, N.; Schmid-Grendelmeier, P.; Serpa, F. S.; Shamai, S.; Sheikh, A.; Sierra, M.; Simons, F. E. R.; Sir-Oux, V.; Sisul, J. C.; Skrindo, I.; Sole, D.; Somekh, D.; Sonder-Mann, M.; Sooronbaev, T.; Sova, M.; Sorensen, M.; Sorlini, M.; Spranger, O.; Stellato, C.; Stelmach, R.; Stukas, R.; Sunyer, J.; Strozek, J.; Szylling, A.; Tebyrica, Jn; Thibaudon, M.; To, T.; Todo-Bom, A.; Tomazic, P. V.; Toppila-Salmi, S.; Trama, U.; Triggiani, M.; Ulrik, C. Suppli; Urrutia-Pereira, M.; Valenta, R.; Valero, A.; Valiulis, A.; Valovirta, E.; Van Eerd, M.; Van Ganse, E.; Van Hague, M.; Vandenplas, O.; Ventura, M. T.; Vezzani, G.; Vasankari, T.; Vatrella, A.; Verissimo, M. T.; Viart, F.; Viegi, G.; Vicheva, D.; Vontetsianos, T.; Wagenmann, M.; Walker, S.; Wallace, D.; Wang, D. Y.; Waserman, S.; Werfel, T.; Westman, M.; Wickman, M.; Williams, D. M.; Williams, S.; Wilson, N.; Wright, J.; Wroczynski, P.; Yakovliev, P.; Yawn, B. P.; Yiallouros, P. K.; Yorgancioglu, A.; Yusuf, O. M.; Zar, H. J.; Zhang, L.; Zhong, N.; Zernotti, M. E.; Zhanat, I.; Zidarn, M.; Zuberbier, T.; Zubrinich, C.; Zurkuhlen, A.

In: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, Vol. 49, No. 4, 04.2019, p. 442-460.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study

AU - Menditto, Enrica

AU - Costa, Elisio

AU - Midao, Luis

AU - Bosnic-Anticevich, Sinthia

AU - Novellino, Ettore

AU - Bialek, Slawomir

AU - Briedis, Vitalis

AU - Mair, Alpana

AU - Rajabian-Soderlund, Rojin

AU - Arnavielhe, Sylvie

AU - Bedbrook, Anna

AU - Czarlewski, Wienczyslawa

AU - Annesi-Maesano, Isabella

AU - Anto, Josep M.

AU - Devillier, Philippe

AU - De Vries, Govert

AU - Keil, Thomas

AU - Sheikh, Aziz

AU - Orlando, Valentina

AU - Larenas-Linnemann, Desiree

AU - Cecchi, Lorenzo

AU - De Feo, Giulia

AU - Illario, M.

AU - Stellato, Cristiana

AU - Fonseca, Joao

AU - Malva, Joao

AU - Morais-Almeida, Mario

AU - Pereira, Ana Maria

AU - Todo-Bom, Ana Maria

AU - Kvedariene, Violeta

AU - Valiulis, Arunas

AU - Bergmann, Karl Christian

AU - Klimek, Ludger

AU - Moesges, Ralph

AU - Pfaar, Oliver

AU - Zuberbier, Torsten

AU - Cardona, Vicky

AU - Mullol, Joaquim

AU - Papadopoulos, Nikos G.

AU - Prokopakis, Emmanuel P.

AU - Bewick, Mike

AU - Ryan, Dermot

AU - Roller-Wirnsberger, Regina E.

AU - Tomazic, Peter Valentin

AU - Cruz, Alvaro A.

AU - Kuna, Piotr

AU - Samolinski, Boleslaw

AU - Fokkens, Wytske J.

AU - Reitsma, Sietze

AU - Bosse, Isabelle

AU - Fontaine, Jean-Francois

AU - Laune, Daniel

AU - Haahtela, Tari

AU - Toppila-Salmi, Sanna

AU - Bachert, Claus

AU - Hellings, Peter W.

AU - Melen, Erik

AU - Wickman, Magnus

AU - Bindslev-Jensen, Carsten

AU - Eller, Esben

AU - O'Hehir, Robyn E.

AU - Cingi, Cemal

AU - Gemicioglu, Bilun

AU - Kalayci, Omer

AU - Ivancevich, Juan Carlos

AU - Bousquet, Jean

AU - Bousquet, J.

AU - Hellings, P. W.

AU - Aberer, W.

AU - Agache, I.

AU - Akdis, C. A.

AU - Akdis, M.

AU - Aliberti, M. R.

AU - Almeida, R.

AU - Amat, F.

AU - Angles, R.

AU - Annesi-Maesano, I.

AU - Ansotegui, I. J.

AU - Anto, J. M.

AU - Arnavielle, S.

AU - Asayag, E.

AU - Asarnoj, A.

AU - Arshad, H.

AU - Avolio, F.

AU - Bacci, E.

AU - Bachert, C.

AU - Baiar-Dini, I.

AU - Barbara, C.

AU - Barbagallo, M.

AU - Baroni, I.

AU - Barreto, B. A.

AU - Basagana, X.

AU - Bateman, E. D.

AU - Bedolla-Barajas, M.

AU - Bedbrook, A.

AU - Bewick, M.

AU - Beghe, B.

AU - Bel, E. H.

AU - Bergmann, K. C.

AU - Bennoor, K. S.

AU - Benson, M.

AU - Bertorello, L.

AU - Bialoszewski, A. Z.

AU - Bieber, T.

AU - Bialek, S.

AU - Bindslev-Jensen, C.

AU - Bjermer, L.

AU - Blain, H.

AU - Blasi, F.

AU - Blua, A.

AU - Marciniak, M. Bochenska

AU - Bogus-Buczynska, I.

AU - Boner, A. L.

AU - Bonini, M.

AU - Bonini, S.

AU - Bosnic-Anticevich, C. S.

AU - Bosse, I.

AU - Bouchard, J.

AU - Boulet, L. P.

AU - Bourret, R.

AU - Bousquet, Pj

AU - Braido, F.

AU - Briedis, V.

AU - Brightling, C. E.

AU - Brozek, J.

AU - Bucca, C.

AU - Buhl, R.

AU - Buonaiuto, R.

AU - Panaitescu, C.

AU - Cabanas, M. T. Burguete

AU - Burte, E.

AU - Bush, A.

AU - Caballero-Fonseca, F.

AU - Caillaud, D.

AU - Caimmi, D.

AU - Calderon, M. A.

AU - Camargos, P. A. M.

AU - Camuzat, T.

AU - Canfora, G.

AU - Canonica, G. W.

AU - Cardona, V.

AU - Carlsen, K. H.

AU - Carreiro-Martins, P.

AU - Carriazo, A. M.

AU - Carr, W.

AU - Cartier, C.

AU - Casale, T.

AU - Castellano, G.

AU - Cecchi, L.

AU - Cepeda, A. M.

AU - Chavannes, N. H.

AU - Chen, Y.

AU - Chiron, R.

AU - Chivato, T.

AU - Chkhartishvili, E.

AU - Chuchalin, A. G.

AU - Chung, K. F.

AU - Ciaravolo, M. M.

AU - Ciceran, A.

AU - Cingi, C.

AU - Ciprandi, G.

AU - Coehlo, A. C. Carvalho

AU - Colas, L.

AU - Colgan, E.

AU - Coll, J.

AU - Conforti, D.

AU - De Sousa, J. Correia

AU - Cortes-Grimaldo, R. M.

AU - Corti, F.

AU - Costa, E.

AU - Mc Costa-Dominguez,

AU - Al Courbis, F.

AU - Cox, L.

AU - Crescenzo, M.

AU - Cruz, A. A.

AU - Custovic, A.

AU - Czarlewski, W.

AU - Dahlen, S. E.

AU - D'Amato,

AU - Dario, C.

AU - da Silva, J.

AU - Dauvilliers, Y.

AU - Darsow, U.

AU - De Blay, F.

AU - De Carlo, G.

AU - Dedeu, T.

AU - Emerson, M. De Fatima

AU - De Feo, G.

AU - De Vries, G.

AU - De Martino, B.

AU - Rubina, N. P. Motta

AU - Deleanu, D.

AU - Demoly, P.

AU - Denburg, Ja

AU - Devillier, P.

AU - Ercolano, S. Di Capua

AU - Di Carluccio, N.

AU - Didier, A.

AU - Dokic, D.

AU - Dominguez-Silva, M. G.

AU - Douagui, H.

AU - Dray, G.

AU - Dubakiene, R.

AU - Durham, S. R.

AU - Du Toit, G.

AU - Dykewicz, M. S.

AU - El-Gamal, Y.

AU - Eklund, P.

AU - Eller, E.

AU - Emuzyte, R.

AU - Farrell, J.

AU - Farsi, A.

AU - De Mello, J. Ferreira, Jr.

AU - Ferrero, J.

AU - Fink-Wagner, A.

AU - Fiocchi, A.

AU - Fok-Kens, W. J.

AU - Fonseca, Ja

AU - Fontaine, J. F.

AU - Forti, S.

AU - Fuentes-Perez, J. M.

AU - Galvez-Romero, J. L.

AU - Gamkrelidze, A.

AU - Garcia-Aymerich, J.

AU - Garcia-Cobas, C. Y.

AU - Garcia-Cruz, M. H.

AU - Gemicioglu, B.

AU - Genova, S.

AU - Christoff, G.

AU - Gereda, J. E.

AU - Van Wijk, R. Gerth

AU - Gomez, R. M.

AU - Gomez-Vera, J.

AU - Diaz, S. Gonzalez

AU - Gotua, M.

AU - Grisle, I.

AU - Guidacci, M.

AU - Guldemond, Na

AU - Gutter, Z.

AU - Guzman, Ma

AU - Haahtela, T.

AU - Hajjam, J.

AU - Hernandez, L.

AU - Houri-Hane, JO'B

AU - Huerta-Villalobos, Y. R.

AU - Humbert, M.

AU - Iaccarino, G.

AU - Illario, M.

AU - Ispayeva, Z.

AU - Ivancevich, J. C.

AU - Jares, Ej

AU - Jassem, E.

AU - Johnston, S. L.

AU - Joos, G.

AU - Jung, K. S.

AU - Just, J.

AU - Jutel, M.

AU - Kaidashev, I.

AU - Kalayci, O.

AU - Kalyoncu, A. F.

AU - Karjalainen, J.

AU - Kardas, P.

AU - Keil, T.

AU - Keith, P. K.

AU - Khaitov, M.

AU - Khaltaev, N.

AU - Kleine-Tebbe, J.

AU - Klimek, L.

AU - Kowalski, M. L.

AU - Kuitunen, M.

AU - Kull, I.

AU - Kuna, P.

AU - Kupczyk, M.

AU - Kvedariene, V.

AU - Krzych-Falta, E.

AU - Lacwik, P.

AU - Larenas-Linnemann, D.

AU - Laune, D.

AU - Lauri, D.

AU - Lavrut, J.

AU - Le, L. T. T.

AU - Lessa, M.

AU - Levato, G.

AU - Li, J.

AU - Lieberman, P.

AU - Liplec, A.

AU - Lipworth, B.

AU - Carlsen, K. C. Lodrup

AU - Louis, R.

AU - Lourenco, O.

AU - Luna-Pech, J. A.

AU - Magnan, A.

AU - Mahboub, B.

AU - Maier, D.

AU - Mair, A.

AU - Majer, I.

AU - Malva, J.

AU - Mandajieva, E.

AU - Manning, P.

AU - Keenoy, E. De Manuel

AU - Marshall, G. D.

AU - Masjedi, M. R.

AU - Maspero, J. F.

AU - Mathieu-Dupas, E.

AU - Campos, J. J. Matta

AU - Al Matos,

AU - Maurer, M.

AU - Mavale-Manuel, S.

AU - Mayora, O.

AU - Medina-Avalos, M. A.

AU - Melen, E.

AU - Melo-Gomes, E.

AU - Meltzer, Eo

AU - Menditto, E.

AU - Mercier, J.

AU - Miculinic, N.

AU - Mihaltan, F.

AU - Milenkovic, B.

AU - Moda, G.

AU - Mogica-Martinez, M. D.

AU - Mohammad, Y.

AU - Momas, I.

AU - Monte-Fort, S.

AU - Monti, R.

AU - Bogado, D. Mora

AU - Morais-Almeida, M.

AU - Morato-Castro,

AU - Mosges, R.

AU - Mota-Pinto, A.

AU - Santo, P. Moura

AU - Mullol, J.

AU - Munter, L.

AU - Muraro, A.

AU - Murray, R.

AU - Naclerio, R.

AU - Nadif, R.

AU - Nalin, M.

AU - Napoli, L.

AU - Namazova-Baranova, L.

AU - Neffen, H.

AU - Niedeberger, V.

AU - Nekam, K.

AU - Neou, A.

AU - Nieto, A.

AU - Nogueira-Silva, L.

AU - Nogues, M.

AU - Novellino, E.

AU - Nyembue, Td

AU - O'Hehir, Re

AU - Odzhakova, C.

AU - Ohta, K.

AU - Okamoto, Y.

AU - Okubo, K.

AU - Onorato, G. L.

AU - Cisneros, M. Ortega

AU - Ouedraogo, S.

AU - Pali-Scholl, I.

AU - Palkonen, S.

AU - Panzner, P.

AU - Papadopoulos, N. G.

AU - Park, H. S.

AU - Papi, A.

AU - Passalacqua, G.

AU - Paulino, E.

AU - Pawankar, R.

AU - Pedersen, S.

AU - Pepin, J. L.

AU - Pereira, A. M.

AU - Persico, M.

AU - Pfaar, O.

AU - Phillips, J.

AU - Picard, R.

AU - Pigearias, B.

AU - Pin, I.

AU - Pitsios, C.

AU - Plavec, D.

AU - Pohl, W.

AU - Popov, T. A.

AU - Portejoie, F.

AU - Potter, P.

AU - Pozzi, A. C.

AU - Price, D.

AU - Prokopakis, E. P.

AU - Puy, R.

AU - Pugin, B.

AU - Ross, R. E. Pulido

AU - Przemecka, M.

AU - Rabe, K. F.

AU - Raciborski, F.

AU - Raja-Bian-Soderlund, R.

AU - Reitsma, S.

AU - Ribeirinho, I.

AU - Rimmer, J.

AU - Riv-Ero-Yeverino, D.

AU - Rizzo, J. A.

AU - Rizzo, M. C.

AU - Robalo-Cordeiro, C.

AU - Rodenas, F.

AU - Rodo, X.

AU - Gonzalez, M. Rodriguez

AU - Rodriguez-Manas, L.

AU - Rolland, C.

AU - Valle, S. Rodrigues

AU - Rodriguez, M. Roman

AU - Romano, A.

AU - Rodriguez-Zagal, E.

AU - Rolla, G.

AU - Roller-Wirnsberger, R. E.

AU - Romano, M.

AU - Rosado-Pinto, J.

AU - Rosario, N.

AU - Rottem, M.

AU - Ryan, D.

AU - Sagara, H.

AU - Salimaki, J.

AU - Samolinski, B.

AU - Sanchez-Borges, M.

AU - Sastre-Dominguez, J.

AU - Scadding, G. K.

AU - Schunemann, H. J.

AU - Scichilone, N.

AU - Schmid-Grendelmeier, P.

AU - Serpa, F. S.

AU - Shamai, S.

AU - Sheikh, A.

AU - Sierra, M.

AU - Simons, F. E. R.

AU - Sir-Oux, V.

AU - Sisul, J. C.

AU - Skrindo, I.

AU - Sole, D.

AU - Somekh, D.

AU - Sonder-Mann, M.

AU - Sooronbaev, T.

AU - Sova, M.

AU - Sorensen, M.

AU - Sorlini, M.

AU - Spranger, O.

AU - Stellato, C.

AU - Stelmach, R.

AU - Stukas, R.

AU - Sunyer, J.

AU - Strozek, J.

AU - Szylling, A.

AU - Tebyrica, Jn

AU - Thibaudon, M.

AU - To, T.

AU - Todo-Bom, A.

AU - Tomazic, P. V.

AU - Toppila-Salmi, S.

AU - Trama, U.

AU - Triggiani, M.

AU - Ulrik, C. Suppli

AU - Urrutia-Pereira, M.

AU - Valenta, R.

AU - Valero, A.

AU - Valiulis, A.

AU - Valovirta, E.

AU - Van Eerd, M.

AU - Van Ganse, E.

AU - Van Hague, M.

AU - Vandenplas, O.

AU - Ventura, M. T.

AU - Vezzani, G.

AU - Vasankari, T.

AU - Vatrella, A.

AU - Verissimo, M. T.

AU - Viart, F.

AU - Viegi, G.

AU - Vicheva, D.

AU - Vontetsianos, T.

AU - Wagenmann, M.

AU - Walker, S.

AU - Wallace, D.

AU - Wang, D. Y.

AU - Waserman, S.

AU - Werfel, T.

AU - Westman, M.

AU - Wickman, M.

AU - Williams, D. M.

AU - Williams, S.

AU - Wilson, N.

AU - Wright, J.

AU - Wroczynski, P.

AU - Yakovliev, P.

AU - Yawn, B. P.

AU - Yiallouros, P. K.

AU - Yorgancioglu, A.

AU - Yusuf, O. M.

AU - Zar, H. J.

AU - Zhang, L.

AU - Zhong, N.

AU - Zernotti, M. E.

AU - Zhanat, I.

AU - Zidarn, M.

AU - Zuberbier, T.

AU - Zubrinich, C.

AU - Zurkuhlen, A.

PY - 2019/4

Y1 - 2019/4

N2 - Background: Mobile technology may help to better understand the adherence to treatment. MASK-rhinitis (Mobile Airways Sentinel NetworK for allergic rhinitis) is a patient-centred ICT system. A mobile phone app (the Allergy Diary) central to MASK is available in 22 countries. Objectives: To assess the adherence to treatment in allergic rhinitis patients using the Allergy Diary App. Methods: An observational cross-sectional study was carried out on all users who filled in the Allergy Diary from 1 January 2016 to 1 August 2017. Secondary adherence was assessed by using the modified Medication Possession Ratio (MPR) and the Proportion of days covered (PDC) approach. Results: A total of 12 143 users were registered. A total of 6 949 users reported at least one VAS data recording. Among them, 1 887 users reported ≥7 VAS data. About 1 195 subjects were included in the analysis of adherence. One hundred and thirty-six (11.28%) users were adherent (MPR ≥70% and PDC ≤1.25), 51 (4.23%) were partly adherent (MPR ≥70% and PDC = 1.50) and 176 (14.60%) were switchers. On the other hand, 832 (69.05%) users were non-adherent to medications (MPR <70%). Of those, the largest group was non-adherent to medications and the time interval was increased in 442 (36.68%) users. Conclusion and clinical relevance: Adherence to treatment is low. The relative efficacy of continuous vs on-demand treatment for allergic rhinitis symptoms is still a matter of debate. This study shows an approach for measuring retrospective adherence based on a mobile app. This also represents a novel approach for analysing medication-taking behaviour in a real-world setting.

AB - Background: Mobile technology may help to better understand the adherence to treatment. MASK-rhinitis (Mobile Airways Sentinel NetworK for allergic rhinitis) is a patient-centred ICT system. A mobile phone app (the Allergy Diary) central to MASK is available in 22 countries. Objectives: To assess the adherence to treatment in allergic rhinitis patients using the Allergy Diary App. Methods: An observational cross-sectional study was carried out on all users who filled in the Allergy Diary from 1 January 2016 to 1 August 2017. Secondary adherence was assessed by using the modified Medication Possession Ratio (MPR) and the Proportion of days covered (PDC) approach. Results: A total of 12 143 users were registered. A total of 6 949 users reported at least one VAS data recording. Among them, 1 887 users reported ≥7 VAS data. About 1 195 subjects were included in the analysis of adherence. One hundred and thirty-six (11.28%) users were adherent (MPR ≥70% and PDC ≤1.25), 51 (4.23%) were partly adherent (MPR ≥70% and PDC = 1.50) and 176 (14.60%) were switchers. On the other hand, 832 (69.05%) users were non-adherent to medications (MPR <70%). Of those, the largest group was non-adherent to medications and the time interval was increased in 442 (36.68%) users. Conclusion and clinical relevance: Adherence to treatment is low. The relative efficacy of continuous vs on-demand treatment for allergic rhinitis symptoms is still a matter of debate. This study shows an approach for measuring retrospective adherence based on a mobile app. This also represents a novel approach for analysing medication-taking behaviour in a real-world setting.

KW - adherence

KW - mHealth

KW - mobile technology

KW - observational study

KW - rhinitis

KW - treatment

U2 - 10.1111/cea.13333

DO - 10.1111/cea.13333

M3 - Article

VL - 49

SP - 442

EP - 460

JO - Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

JF - Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

SN - 0954-7894

IS - 4

ER -