A Workflow for the Application of Biclustering to Mass Spectrometry Data

H. López-Fernández; Miguel Reboiro-Jato; S. C. Madeira; Rubén López-Cortés; Júlio D. Nunes-Miranda; H. M. Santos; Florentino Fdez-Riverola; D. Glez-Peña

doi:10.1007/978-3-319-00578-2_19

A Workflow for the Application of Biclustering to Mass Spectrometry Data

H. López-Fernández, Miguel Reboiro-Jato, S. C. Madeira, Rubén López-Cortés, Júlio D. Nunes-Miranda, H. M. Santos, Florentino Fdez-Riverola, D. Glez-Peña

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

3 Citations (Scopus)

Abstract

Biclustering techniques have been successfully applied to analyze microarray data and they begin to be applied to the analysis of mass spectrometry data, a high-throughput technology for proteomic data analysis which has been an active research area during the last years. In this work, we propose a novel workflow to the application of biclustering to MALDI-TOF mass spectrometry data, supported by a software desktop application which covering all of its stages. We evaluate the adequacy of applying biclustering to analyze mass spectrometry by comparing between biclustering and hierarchical clustering over two real datasets. Results are promising since they revealed the ability of these techniques to extract useful information, opening a door to further works. © Springer International Publishing Switzerland 2013.

Original language	English
Title of host publication	7th International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB 2013)
Editors	M. Mohamad , L. Nanni, M. Rocha , F. Fdez-Riverola
Place of Publication	Heidelberg
Publisher	Springer International Publishing
Pages	145-153
Number of pages	9
ISBN (Electronic)	978-3-319-00578-2
ISBN (Print)	978-3-319-00577-5
DOIs	https://doi.org/10.1007/978-3-319-00578-2_19
Publication status	Published - 2013
Event	7th International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB 2013) - Salamanca, Spain Duration: 22 May 2013 → 24 May 2013 Conference number: 7th

Publication series

Name	Advances in Intelligent Systems and Computing
Publisher	Springer International Publishing
Volume	222
ISSN (Print)	2194-5357
ISSN (Electronic)	2194-5365

Conference

Conference	7th International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB 2013)
Abbreviated title	PACBB 2013
Country/Territory	Spain
City	Salamanca
Period	22/05/13 → 24/05/13

Keywords

BiBit
biclustering
Bimax
BiMS
mass spectrometry
Application programs
Bioinformatics
Data processing
Bi-clustering
Hier-archical clustering
High-throughput technologies
MALDI-TOF mass spectrometry
Mass spectrometry data
Mass spectrometry

Access to Document

10.1007/978-3-319-00578-2_19

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84880375507&doi=10.1007%2f978-3-319-00578-2_19&partnerID=40&md5=5ca14bafed59d97986f1872b757bb8c8

Cite this

López-Fernández, H., Reboiro-Jato, M., Madeira, S. C., López-Cortés, R., Nunes-Miranda, J. D., Santos, H. M., Fdez-Riverola, F., & Glez-Peña, D. (2013). A Workflow for the Application of Biclustering to Mass Spectrometry Data. In M. Mohamad , L. Nanni, M. Rocha , & F. Fdez-Riverola (Eds.), 7th International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB 2013) (pp. 145-153). (Advances in Intelligent Systems and Computing; Vol. 222). Springer International Publishing. https://doi.org/10.1007/978-3-319-00578-2_19

López-Fernández, H. ; Reboiro-Jato, Miguel ; Madeira, S. C. et al. / A Workflow for the Application of Biclustering to Mass Spectrometry Data. 7th International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB 2013). editor / M. Mohamad ; L. Nanni ; M. Rocha ; F. Fdez-Riverola. Heidelberg : Springer International Publishing, 2013. pp. 145-153 (Advances in Intelligent Systems and Computing).

@inproceedings{742dffddde4741119de07490e9214142,

title = "A Workflow for the Application of Biclustering to Mass Spectrometry Data",

abstract = "Biclustering techniques have been successfully applied to analyze microarray data and they begin to be applied to the analysis of mass spectrometry data, a high-throughput technology for proteomic data analysis which has been an active research area during the last years. In this work, we propose a novel workflow to the application of biclustering to MALDI-TOF mass spectrometry data, supported by a software desktop application which covering all of its stages. We evaluate the adequacy of applying biclustering to analyze mass spectrometry by comparing between biclustering and hierarchical clustering over two real datasets. Results are promising since they revealed the ability of these techniques to extract useful information, opening a door to further works. {\textcopyright} Springer International Publishing Switzerland 2013.",

keywords = "BiBit, biclustering, Bimax, BiMS, mass spectrometry, Application programs, Bioinformatics, Data processing, Bi-clustering, Hier-archical clustering, High-throughput technologies, MALDI-TOF mass spectrometry, Mass spectrometry data, Mass spectrometry",

author = "H. L{\'o}pez-Fern{\'a}ndez and Miguel Reboiro-Jato and Madeira, {S. C.} and Rub{\'e}n L{\'o}pez-Cort{\'e}s and Nunes-Miranda, {J{\'u}lio D.} and Santos, {H. M.} and Florentino Fdez-Riverola and D. Glez-Pe{\~n}a",

year = "2013",

doi = "10.1007/978-3-319-00578-2_19",

language = "English",

isbn = "978-3-319-00577-5",

series = "Advances in Intelligent Systems and Computing",

publisher = "Springer International Publishing",

pages = "145--153",

editor = "{Mohamad }, M. and L. Nanni and {Rocha }, M. and F. Fdez-Riverola",

booktitle = "7th International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB 2013)",

note = "7th International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB 2013), PACBB 2013 ; Conference date: 22-05-2013 Through 24-05-2013",

}

López-Fernández, H, Reboiro-Jato, M, Madeira, SC, López-Cortés, R, Nunes-Miranda, JD, Santos, HM, Fdez-Riverola, F & Glez-Peña, D 2013, A Workflow for the Application of Biclustering to Mass Spectrometry Data. in M Mohamad , L Nanni, M Rocha & F Fdez-Riverola (eds), 7th International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB 2013). Advances in Intelligent Systems and Computing, vol. 222, Springer International Publishing, Heidelberg, pp. 145-153, 7th International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB 2013), Salamanca, Spain, 22/05/13. https://doi.org/10.1007/978-3-319-00578-2_19

A Workflow for the Application of Biclustering to Mass Spectrometry Data. / López-Fernández, H.; Reboiro-Jato, Miguel; Madeira, S. C. et al.
7th International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB 2013). ed. / M. Mohamad ; L. Nanni; M. Rocha ; F. Fdez-Riverola. Heidelberg: Springer International Publishing, 2013. p. 145-153 (Advances in Intelligent Systems and Computing; Vol. 222).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - A Workflow for the Application of Biclustering to Mass Spectrometry Data

AU - López-Fernández, H.

AU - Reboiro-Jato, Miguel

AU - Madeira, S. C.

AU - López-Cortés, Rubén

AU - Nunes-Miranda, Júlio D.

AU - Santos, H. M.

AU - Fdez-Riverola, Florentino

AU - Glez-Peña, D.

N1 - Conference code: 7th

PY - 2013

Y1 - 2013

N2 - Biclustering techniques have been successfully applied to analyze microarray data and they begin to be applied to the analysis of mass spectrometry data, a high-throughput technology for proteomic data analysis which has been an active research area during the last years. In this work, we propose a novel workflow to the application of biclustering to MALDI-TOF mass spectrometry data, supported by a software desktop application which covering all of its stages. We evaluate the adequacy of applying biclustering to analyze mass spectrometry by comparing between biclustering and hierarchical clustering over two real datasets. Results are promising since they revealed the ability of these techniques to extract useful information, opening a door to further works. © Springer International Publishing Switzerland 2013.

AB - Biclustering techniques have been successfully applied to analyze microarray data and they begin to be applied to the analysis of mass spectrometry data, a high-throughput technology for proteomic data analysis which has been an active research area during the last years. In this work, we propose a novel workflow to the application of biclustering to MALDI-TOF mass spectrometry data, supported by a software desktop application which covering all of its stages. We evaluate the adequacy of applying biclustering to analyze mass spectrometry by comparing between biclustering and hierarchical clustering over two real datasets. Results are promising since they revealed the ability of these techniques to extract useful information, opening a door to further works. © Springer International Publishing Switzerland 2013.

KW - BiBit

KW - biclustering

KW - Bimax

KW - BiMS

KW - mass spectrometry

KW - Application programs

KW - Bioinformatics

KW - Data processing

KW - Bi-clustering

KW - Hier-archical clustering

KW - High-throughput technologies

KW - MALDI-TOF mass spectrometry

KW - Mass spectrometry data

KW - Mass spectrometry

U2 - 10.1007/978-3-319-00578-2_19

DO - 10.1007/978-3-319-00578-2_19

M3 - Conference contribution

SN - 978-3-319-00577-5

T3 - Advances in Intelligent Systems and Computing

SP - 145

EP - 153

BT - 7th International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB 2013)

A2 - Mohamad , M.

A2 - Nanni, L.

A2 - Rocha , M.

A2 - Fdez-Riverola, F.

PB - Springer International Publishing

CY - Heidelberg

T2 - 7th International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB 2013)

Y2 - 22 May 2013 through 24 May 2013

ER -

López-Fernández H, Reboiro-Jato M, Madeira SC, López-Cortés R, Nunes-Miranda JD, Santos HM et al. A Workflow for the Application of Biclustering to Mass Spectrometry Data. In Mohamad M, Nanni L, Rocha M, Fdez-Riverola F, editors, 7th International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB 2013). Heidelberg: Springer International Publishing. 2013. p. 145-153. (Advances in Intelligent Systems and Computing). doi: 10.1007/978-3-319-00578-2_19

A Workflow for the Application of Biclustering to Mass Spectrometry Data

Abstract

Publication series

Conference

Keywords

Access to Document

Fingerprint

Cite this