A simple sol-gel route to the construction of hydroxyapatite inverted colloidal crystals for bone tissue engineering

Carlos João; Rute Almeida; Jorge AMC Silva; João Borges

doi:10.1016/j.matlet.2016.09.030

A simple sol-gel route to the construction of hydroxyapatite inverted colloidal crystals for bone tissue engineering

Carlos João, Rute Almeida, Jorge AMC Silva, João Borges

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

Abstract

Hydroxyapatite (HAp) scaffolds with uniform pore size and interconnected pore network were constructed based on the inverted colloidal crystal (ICC) geometry and a simple sol-gel formulation. Monodisperse polystyrene microspheres were self-assembled and annealed into a hexagonal close packed structure. HAp sol-gel was infiltrated in this template followed by thermal treatment for simultaneous HAp matrix sintering and polymeric colloidal crystal calcination. The resultant ICC scaffolds exhibit an ordered architecture that was able to offer a favorable environment for human osteoblasts adhesion and proliferation, an essential feature for bone ingrowth in tissue engineering applications.

Original language	English
Pages (from-to)	407-410
Number of pages	4
Journal	Materials Letters
Volume	185
DOIs	https://doi.org/10.1016/j.matlet.2016.09.030
Publication status	Published - 15 Dec 2016

Keywords

Hydroxyapatite
Sol-gel
Inverted colloidal crystals
Bone tissue engineering

Access to Document

10.1016/j.matlet.2016.09.030Licence: CC BY-NC-ND

http://www.sciencedirect.com/science/article/pii/S0167577X16314987

Cite this

@article{7a6361477fc44894a6ceb4ac293fb735,

title = "A simple sol-gel route to the construction of hydroxyapatite inverted colloidal crystals for bone tissue engineering",

abstract = "Hydroxyapatite (HAp) scaffolds with uniform pore size and interconnected pore network were constructed based on the inverted colloidal crystal (ICC) geometry and a simple sol-gel formulation. Monodisperse polystyrene microspheres were self-assembled and annealed into a hexagonal close packed structure. HAp sol-gel was infiltrated in this template followed by thermal treatment for simultaneous HAp matrix sintering and polymeric colloidal crystal calcination. The resultant ICC scaffolds exhibit an ordered architecture that was able to offer a favorable environment for human osteoblasts adhesion and proliferation, an essential feature for bone ingrowth in tissue engineering applications.",

keywords = "Hydroxyapatite, Sol-gel, Inverted colloidal crystals, Bone tissue engineering",

author = "Carlos Jo{\~a}o and Rute Almeida and {AMC Silva}, Jorge and Jo{\~a}o Borges",

note = "Sem PDF conforme despacho. info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F80860%2F2011/PT# Portuguese Foundation for Science and Technology - POCL-01-0145-FEDER-007688; ; SFRH/BD/80860/2011 ",

year = "2016",

month = dec,

day = "15",

doi = "10.1016/j.matlet.2016.09.030",

language = "English",

volume = "185",

pages = "407--410",

journal = "Materials Letters",

issn = "0167-577X",

publisher = "Elsevier Science B.V., Inc",

}

TY - JOUR

T1 - A simple sol-gel route to the construction of hydroxyapatite inverted colloidal crystals for bone tissue engineering

AU - João, Carlos

AU - Almeida, Rute

AU - AMC Silva, Jorge

AU - Borges, João

N1 - Sem PDF conforme despacho. info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F80860%2F2011/PT# Portuguese Foundation for Science and Technology - POCL-01-0145-FEDER-007688; ; SFRH/BD/80860/2011

PY - 2016/12/15

Y1 - 2016/12/15

N2 - Hydroxyapatite (HAp) scaffolds with uniform pore size and interconnected pore network were constructed based on the inverted colloidal crystal (ICC) geometry and a simple sol-gel formulation. Monodisperse polystyrene microspheres were self-assembled and annealed into a hexagonal close packed structure. HAp sol-gel was infiltrated in this template followed by thermal treatment for simultaneous HAp matrix sintering and polymeric colloidal crystal calcination. The resultant ICC scaffolds exhibit an ordered architecture that was able to offer a favorable environment for human osteoblasts adhesion and proliferation, an essential feature for bone ingrowth in tissue engineering applications.

AB - Hydroxyapatite (HAp) scaffolds with uniform pore size and interconnected pore network were constructed based on the inverted colloidal crystal (ICC) geometry and a simple sol-gel formulation. Monodisperse polystyrene microspheres were self-assembled and annealed into a hexagonal close packed structure. HAp sol-gel was infiltrated in this template followed by thermal treatment for simultaneous HAp matrix sintering and polymeric colloidal crystal calcination. The resultant ICC scaffolds exhibit an ordered architecture that was able to offer a favorable environment for human osteoblasts adhesion and proliferation, an essential feature for bone ingrowth in tissue engineering applications.

KW - Hydroxyapatite

KW - Sol-gel

KW - Inverted colloidal crystals

KW - Bone tissue engineering

U2 - 10.1016/j.matlet.2016.09.030

DO - 10.1016/j.matlet.2016.09.030

M3 - Article

SN - 0167-577X

VL - 185

SP - 407

EP - 410

JO - Materials Letters

JF - Materials Letters

ER -

A simple sol-gel route to the construction of hydroxyapatite inverted colloidal crystals for bone tissue engineering

Abstract

Keywords

Access to Document

Fingerprint

Cite this