A safety assessment of Coriolus versicolor biomass as a food supplement

AB Barros, Jorge Ferrão, Tito Fernandes

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)
30 Downloads (Pure)


Background: Coriolus versicolor (CV) is a common mushroom with antitumor, anti-inflammatory, antioxidant, antiviral, antibacterial, and immunomodulatory properties. The existence of these properties has been extensively proven mainly using CV extract; research on the biomass form is scarce. Objective: The aim of this study was to investigate the safety of the CV biomass form, as it is commonly used as a food supplement. Design: CV biomass powder was dissolved in distilled water and administered daily (2.5, 5.0, and 7.5 g/kg live weight) in single doses by gavage to both female and male Charles River albino rats. Results: No adverse or lethal effects were observed as a consequence of the daily administration of CV biomass. In addition, compared with the control group, no abnormal findings were observed at necropsy and histopathological examination. Conclusions: A safe profile of CV biomass for human consumption can be inferred from the absence of any remarkable adverse effects in rats.

Original languageEnglish
Article numbere29953
JournalFood and Nutrition Research
Publication statusPublished - 10 Mar 2016


  • Biomass
  • Coriolus versicolor
  • Food supplement
  • Mushrooms
  • Safety assessment


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