A public HTLV-1 molecular epidemiology database for sequence management and data mining.

Thessika Hialla Almeida Araujo , Leandro Inacio Souza-Brito, Pieter Libin,, Koen Deforche, Dustin Edwards, Antonio Eduardo de Albuquerque-Junior, Anne-mieke Vandamme, Anne-Mieke Vandamme, Bernardo Galvao-Castro, Luiz Carlos Junior Alcantara

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

It is estimated that 15 to 20 million people are infected with the human T-cell lymphotropic virus type 1 (HTLV-1). At present, there are more than 2,000 unique HTLV-1 isolate sequences published. A central database to aggregate sequence information from a range of epidemiological aspects including HTLV-1 infections, pathogenesis, origins, and evolutionary dynamics would be useful to scientists and physicians worldwide. Described here, we have developed a database that collects and annotates sequence data and can be accessed through a user-friendly search interface. The HTLV-1 Molecular Epidemiology Database website is available at http://htlv1db.bahia.fiocruz.br/.
Original languageEnglish
Pages (from-to)e42123
JournalPLoS ONE
Volume7
Issue number9
DOIs
Publication statusPublished - 10 Sep 2012

Keywords

  • genetics
  • human
  • age
  • HTLV-1 infections
  • asymptomatic infection
  • data mining
  • epidemiological data
  • gene sequence
  • genotype
  • cell lymphotropic
  • Human T cel leukemia virus infection
  • molecular epidemiology
  • nonhuman
  • virus gene

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