A GBF1-Dependent Mechanism for Environmentally Responsive Regulation of ER-Golgi Transport

Mafalda Lopes-da-Silva, Jessica J. McCormack, Jemima J. Burden, Kimberly J. Harrison-Lavoie, Francesco Ferraro, Daniel F. Cutler

Research output: Contribution to journalArticle

Abstract

da Silva et al. examine how the secretory pathway is coupled to environmental cues. They show that suppression of GBF1, the GEF for two Golgi Arfs (1 and 4), slows exit from the ER and the TGN. GBF1 can be phosphorylated by AMPK, and metabolic activation or inhibition of AMPK controls anterograde traffic.

Original languageEnglish
Pages (from-to)786-+
JournalDevelopmental Cell
Volume49
Issue number5
DOIs
Publication statusPublished - 3 Jun 2019

Cite this

Lopes-da-Silva, M., McCormack, J. J., Burden, J. J., Harrison-Lavoie, K. J., Ferraro, F., & Cutler, D. F. (2019). A GBF1-Dependent Mechanism for Environmentally Responsive Regulation of ER-Golgi Transport. Developmental Cell, 49(5), 786-+. https://doi.org/10.1016/j.devcel.2019.04.006
Lopes-da-Silva, Mafalda ; McCormack, Jessica J. ; Burden, Jemima J. ; Harrison-Lavoie, Kimberly J. ; Ferraro, Francesco ; Cutler, Daniel F. / A GBF1-Dependent Mechanism for Environmentally Responsive Regulation of ER-Golgi Transport. In: Developmental Cell. 2019 ; Vol. 49, No. 5. pp. 786-+.
@article{7e09495ce5c4470b9c1836d8c110f6c2,
title = "A GBF1-Dependent Mechanism for Environmentally Responsive Regulation of ER-Golgi Transport",
abstract = "da Silva et al. examine how the secretory pathway is coupled to environmental cues. They show that suppression of GBF1, the GEF for two Golgi Arfs (1 and 4), slows exit from the ER and the TGN. GBF1 can be phosphorylated by AMPK, and metabolic activation or inhibition of AMPK controls anterograde traffic.",
author = "Mafalda Lopes-da-Silva and McCormack, {Jessica J.} and Burden, {Jemima J.} and Harrison-Lavoie, {Kimberly J.} and Francesco Ferraro and Cutler, {Daniel F.}",
year = "2019",
month = "6",
day = "3",
doi = "10.1016/j.devcel.2019.04.006",
language = "English",
volume = "49",
pages = "786--+",
journal = "Developmental Cell",
issn = "1534-5807",
publisher = "Elsevier Science B.V., Amsterdam.",
number = "5",

}

A GBF1-Dependent Mechanism for Environmentally Responsive Regulation of ER-Golgi Transport. / Lopes-da-Silva, Mafalda; McCormack, Jessica J.; Burden, Jemima J.; Harrison-Lavoie, Kimberly J.; Ferraro, Francesco; Cutler, Daniel F.

In: Developmental Cell, Vol. 49, No. 5, 03.06.2019, p. 786-+.

Research output: Contribution to journalArticle

TY - JOUR

T1 - A GBF1-Dependent Mechanism for Environmentally Responsive Regulation of ER-Golgi Transport

AU - Lopes-da-Silva, Mafalda

AU - McCormack, Jessica J.

AU - Burden, Jemima J.

AU - Harrison-Lavoie, Kimberly J.

AU - Ferraro, Francesco

AU - Cutler, Daniel F.

PY - 2019/6/3

Y1 - 2019/6/3

N2 - da Silva et al. examine how the secretory pathway is coupled to environmental cues. They show that suppression of GBF1, the GEF for two Golgi Arfs (1 and 4), slows exit from the ER and the TGN. GBF1 can be phosphorylated by AMPK, and metabolic activation or inhibition of AMPK controls anterograde traffic.

AB - da Silva et al. examine how the secretory pathway is coupled to environmental cues. They show that suppression of GBF1, the GEF for two Golgi Arfs (1 and 4), slows exit from the ER and the TGN. GBF1 can be phosphorylated by AMPK, and metabolic activation or inhibition of AMPK controls anterograde traffic.

U2 - 10.1016/j.devcel.2019.04.006

DO - 10.1016/j.devcel.2019.04.006

M3 - Article

VL - 49

SP - 786-+

JO - Developmental Cell

JF - Developmental Cell

SN - 1534-5807

IS - 5

ER -