TY - JOUR
T1 - A formal synthesis of (±)-physostigmine via 3,3-rearrangement of a bis-enamine
AU - Santos, Paulo F.
AU - Srinivasan, Natarajan
AU - Almeida, Paulo S.
AU - Lobo, Ana M.
AU - Prabhakar, Sundaresan
PY - 2005/9/19
Y1 - 2005/9/19
N2 - A new flexible approach to hexahydropyrrolo[2,3-b]indole system via the [3,3]-sigmatropic rearrangement of 1-(2′-methoxycarbonyl-N- methylvinylamino)skatole, culminating in the synthesis of (±)- desoxyeseroline, is described.
AB - A new flexible approach to hexahydropyrrolo[2,3-b]indole system via the [3,3]-sigmatropic rearrangement of 1-(2′-methoxycarbonyl-N- methylvinylamino)skatole, culminating in the synthesis of (±)- desoxyeseroline, is described.
KW - Enamines
KW - Eseroline
KW - Physostigmine
KW - Sigmatropic rearrangements
UR - http://www.scopus.com/inward/record.url?scp=23944510845&partnerID=8YFLogxK
U2 - 10.1016/j.tet.2005.07.030
DO - 10.1016/j.tet.2005.07.030
M3 - Article
SN - 0040-4020
VL - 61
SP - 9147
EP - 9156
JO - Tetrahedron
JF - Tetrahedron
IS - 38
ER -