A Clinical Decision Support System for Breast Cancer Patients

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Abstract

This paper proposes a Web clinical decision support system for clinical oncologists and for breast cancer patients making prognostic assessments, using the particular characteristics of the individual patient. This system comprises three different prognostic modelling methodologies: the clinically widely used Nottingham prognostic index (NPI); the Cox regression modelling and a partial logistic artificial neural network with automatic relevance determination (PLANN-ARD). All three models yield a different prognostic index that can be analysed together in order to obtain a more accurate prognostic assessment of the patient. Missing data is incorporated in the mentioned models, a common issue in medical data that was overcome using multiple imputation techniques. Risk group assignments are also provided through a methodology based on regression trees, where Boolean rules can be obtained expressed with patient characteristics.
Original languageUnknown
Title of host publicationIFIP Advances in Information and Communication Technology
Pages122-129
Volume314
DOIs
Publication statusPublished - 1 Jan 2010
EventDOCEIS 2010 -
Duration: 1 Jan 2010 → …

Conference

ConferenceDOCEIS 2010
Period1/01/10 → …

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