A 2-year longitudinal seroepidemiological evaluation of toxoplasma gondii antibodies in a cohort of autochthonous sheep from central Portugal

Daniela Almeida; João Quirino; Patrícia Ferreira Barradas; Priscilla Gomes da Silva; Maria A. Pereira; Rita Cruz; Carla Santos; Ana Cristina Mega; Fernando Esteves; Carmen Nóbrega; Helena Vala; Fátima Gärtner; Irina Amorim; João R. Mesquita

doi:10.3390/pathogens10010040

A 2-year longitudinal seroepidemiological evaluation of toxoplasma gondii antibodies in a cohort of autochthonous sheep from central Portugal

Daniela Almeida, João Quirino, Patrícia Ferreira Barradas, Priscilla Gomes da Silva, Maria A. Pereira, Rita Cruz, Carla Santos, Ana Cristina Mega, Fernando Esteves, Carmen Nóbrega, Helena Vala, Fátima Gärtner, Irina Amorim, João R. Mesquita

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Abstract

(1) Background: Toxoplasma gondii is an important zoonosis and one of the major causes of abortion in sheep worldwide. (2) Methods: We performed a 2-year longitudinal serological anti-T. gondii IgG screening on a cohort of a spatially confined population of a Portuguese autochthonous sheep breed in central Portugal. (3) Results: From the screening of the 2015 and 2016 sera, an increase of seroprevalence was observed (57.7% (95% CI: 49.9–65.3%) versus 69.1% (95% CI: 61.5–75.9), from 2015 and 2016, respectively) (p = 0.031). (4) Conclusions The present study is the first to provide prospective data on the anti-T. gondii serological status of a sheep cohort in Portugal, showing an increase in the occurrence of T. gondii. There is a need to provide a clearer understanding of T. gondii epidemiology in Portugal, ideally by implementing monitoring programs on sentinel herds, not only due to the high impact of T. gondii on animal health but also for it being a zoonosis.

Original language	English
Article number	40
Pages (from-to)	1-6
Number of pages	6
Journal	Pathogens
Volume	10
Issue number	1
DOIs	https://doi.org/10.3390/pathogens10010040
Publication status	Published - 6 Jan 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 2 Zero Hunger
SDG 3 Good Health and Well-being
SDG 12 Responsible Consumption and Production
SDG 15 Life on Land

Keywords

Epidemiology
Serology
Sheep
Toxoplasma gondii

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10.3390/pathogens10010040Licence: CC BY

A 2-Year Longitudinal SeroepidemiologicalFinal published version, 245 KBLicence: CC BY

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Almeida, D., Quirino, J., Barradas, P. F., da Silva, P. G., Pereira, M. A., Cruz, R., Santos, C., Mega, A. C., Esteves, F., Nóbrega, C., Vala, H., Gärtner, F., Amorim, I., & Mesquita, J. R. (2021). A 2-year longitudinal seroepidemiological evaluation of toxoplasma gondii antibodies in a cohort of autochthonous sheep from central Portugal. Pathogens, 10(1), 1-6. Article 40. https://doi.org/10.3390/pathogens10010040

@article{f66f6fbaca4c46ad9d4916001909e61e,

title = "A 2-year longitudinal seroepidemiological evaluation of toxoplasma gondii antibodies in a cohort of autochthonous sheep from central Portugal",

abstract = "(1) Background: Toxoplasma gondii is an important zoonosis and one of the major causes of abortion in sheep worldwide. (2) Methods: We performed a 2-year longitudinal serological anti-T. gondii IgG screening on a cohort of a spatially confined population of a Portuguese autochthonous sheep breed in central Portugal. (3) Results: From the screening of the 2015 and 2016 sera, an increase of seroprevalence was observed (57.7\% (95\% CI: 49.9–65.3\%) versus 69.1\% (95\% CI: 61.5–75.9), from 2015 and 2016, respectively) (p = 0.031). (4) Conclusions The present study is the first to provide prospective data on the anti-T. gondii serological status of a sheep cohort in Portugal, showing an increase in the occurrence of T. gondii. There is a need to provide a clearer understanding of T. gondii epidemiology in Portugal, ideally by implementing monitoring programs on sentinel herds, not only due to the high impact of T. gondii on animal health but also for it being a zoonosis.",

keywords = "Epidemiology, Serology, Sheep, Toxoplasma gondii",

author = "Daniela Almeida and Jo{\~a}o Quirino and Barradas, \{Patr{\'i}cia Ferreira\} and \{da Silva\}, \{Priscilla Gomes\} and Pereira, \{Maria A.\} and Rita Cruz and Carla Santos and Mega, \{Ana Cristina\} and Fernando Esteves and Carmen N{\'o}brega and Helena Vala and F{\'a}tima G{\"a}rtner and Irina Amorim and Mesquita, \{Jo{\~a}o R.\}",

note = "Funding Information: Funding: This research was funded by the National Funds by FCT—Portuguese Foundation for Science and Technology, under the project UIDB/04033/2020. PGdS thanks FCT for the financial support of her PhD work (2020.07806.BD) contract through the DOCTORATES 4 COVID-19 program. Publisher Copyright: {\textcopyright} 2021 by the authors.",

year = "2021",

month = jan,

day = "6",

doi = "10.3390/pathogens10010040",

language = "English",

volume = "10",

pages = "1--6",

journal = "Pathogens",

issn = "2076-0817",

publisher = "MDPI - Multidisciplinary Digital Publishing Institute",

number = "1",

}

Almeida, D, Quirino, J, Barradas, PF, da Silva, PG, Pereira, MA, Cruz, R, Santos, C, Mega, AC, Esteves, F, Nóbrega, C, Vala, H, Gärtner, F, Amorim, I & Mesquita, JR 2021, 'A 2-year longitudinal seroepidemiological evaluation of toxoplasma gondii antibodies in a cohort of autochthonous sheep from central Portugal', Pathogens, vol. 10, no. 1, 40, pp. 1-6. https://doi.org/10.3390/pathogens10010040

TY - JOUR

T1 - A 2-year longitudinal seroepidemiological evaluation of toxoplasma gondii antibodies in a cohort of autochthonous sheep from central Portugal

AU - Almeida, Daniela

AU - Quirino, João

AU - Barradas, Patrícia Ferreira

AU - da Silva, Priscilla Gomes

AU - Pereira, Maria A.

AU - Cruz, Rita

AU - Santos, Carla

AU - Mega, Ana Cristina

AU - Esteves, Fernando

AU - Nóbrega, Carmen

AU - Vala, Helena

AU - Gärtner, Fátima

AU - Amorim, Irina

AU - Mesquita, João R.

N1 - Funding Information: Funding: This research was funded by the National Funds by FCT—Portuguese Foundation for Science and Technology, under the project UIDB/04033/2020. PGdS thanks FCT for the financial support of her PhD work (2020.07806.BD) contract through the DOCTORATES 4 COVID-19 program. Publisher Copyright: © 2021 by the authors.

PY - 2021/1/6

Y1 - 2021/1/6

N2 - (1) Background: Toxoplasma gondii is an important zoonosis and one of the major causes of abortion in sheep worldwide. (2) Methods: We performed a 2-year longitudinal serological anti-T. gondii IgG screening on a cohort of a spatially confined population of a Portuguese autochthonous sheep breed in central Portugal. (3) Results: From the screening of the 2015 and 2016 sera, an increase of seroprevalence was observed (57.7% (95% CI: 49.9–65.3%) versus 69.1% (95% CI: 61.5–75.9), from 2015 and 2016, respectively) (p = 0.031). (4) Conclusions The present study is the first to provide prospective data on the anti-T. gondii serological status of a sheep cohort in Portugal, showing an increase in the occurrence of T. gondii. There is a need to provide a clearer understanding of T. gondii epidemiology in Portugal, ideally by implementing monitoring programs on sentinel herds, not only due to the high impact of T. gondii on animal health but also for it being a zoonosis.

AB - (1) Background: Toxoplasma gondii is an important zoonosis and one of the major causes of abortion in sheep worldwide. (2) Methods: We performed a 2-year longitudinal serological anti-T. gondii IgG screening on a cohort of a spatially confined population of a Portuguese autochthonous sheep breed in central Portugal. (3) Results: From the screening of the 2015 and 2016 sera, an increase of seroprevalence was observed (57.7% (95% CI: 49.9–65.3%) versus 69.1% (95% CI: 61.5–75.9), from 2015 and 2016, respectively) (p = 0.031). (4) Conclusions The present study is the first to provide prospective data on the anti-T. gondii serological status of a sheep cohort in Portugal, showing an increase in the occurrence of T. gondii. There is a need to provide a clearer understanding of T. gondii epidemiology in Portugal, ideally by implementing monitoring programs on sentinel herds, not only due to the high impact of T. gondii on animal health but also for it being a zoonosis.

KW - Epidemiology

KW - Serology

KW - Sheep

KW - Toxoplasma gondii

UR - https://www.scopus.com/pages/publications/85099421065

U2 - 10.3390/pathogens10010040

DO - 10.3390/pathogens10010040

M3 - Article

C2 - 33419095

AN - SCOPUS:85099421065

SN - 2076-0817

VL - 10

SP - 1

EP - 6

JO - Pathogens

JF - Pathogens

IS - 1

M1 - 40

ER -

A 2-year longitudinal seroepidemiological evaluation of toxoplasma gondii antibodies in a cohort of autochthonous sheep from central Portugal

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Keywords

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