TY - JOUR
T1 - 8,15-Epoxylabdane and norlabdane diterpenoids from Eragrostis viscosa
AU - Gaspar, Jorge Francisco Dias Rodrigues
AU - Martins, Célia Maria da Silva
AU - Rueff, José
PY - 2010/1/1
Y1 - 2010/1/1
N2 - Four labdanes with a 8 alpha,15-epoxy ring (8 alpha,15-epoxylabdan-16 beta-oic acid; 8 alpha,15-epoxy-16-norlabdan-13-one; 8 alpha,15-epoxy-16-norlabdane; and 16-acetoxy-8 alpha, 15-epoxylabdane) and the known compound ambreinolide were isolated from the hexane extract of the aerial parts of the grass Eragrostis viscosa. The structures of all compounds were established based on spectroscopic data and the X-ray analysis of 8 alpha,15-epoxy-16-norlabdan-13-one. The hexane extract presented moderate activity against the snail Biomphalaria glabrata. 8 alpha,15-Epoxylabdan-16 beta-oic acid showed no mutagenic activity for doses up to 1000 mu g/plate and no significant clastogenic activity for doses up to 100 mu g/ml. (C) 2010 Elsevier Ltd. All rights reserved.
AB - Four labdanes with a 8 alpha,15-epoxy ring (8 alpha,15-epoxylabdan-16 beta-oic acid; 8 alpha,15-epoxy-16-norlabdan-13-one; 8 alpha,15-epoxy-16-norlabdane; and 16-acetoxy-8 alpha, 15-epoxylabdane) and the known compound ambreinolide were isolated from the hexane extract of the aerial parts of the grass Eragrostis viscosa. The structures of all compounds were established based on spectroscopic data and the X-ray analysis of 8 alpha,15-epoxy-16-norlabdan-13-one. The hexane extract presented moderate activity against the snail Biomphalaria glabrata. 8 alpha,15-Epoxylabdan-16 beta-oic acid showed no mutagenic activity for doses up to 1000 mu g/plate and no significant clastogenic activity for doses up to 100 mu g/ml. (C) 2010 Elsevier Ltd. All rights reserved.
KW - Eragrostis viscosa Poaceae Diterpenes 8
KW - 15-Epoxylabdanes Molluscicide activity Mutagenic activity Clastogenic activity molluscicidal activity
U2 - 10.1016/j.phytochem.2010.02.003
DO - 10.1016/j.phytochem.2010.02.003
M3 - Article
C2 - 20189613
SN - 0031-9422
VL - 71
SP - 798
EP - 803
JO - Phytochemistry
JF - Phytochemistry
IS - 7
ER -