1-Aza-1',3'-diaza-3,3'-sigmatropic rearrangements - A convenient synthesis of benzimidazole derivatives

Maria Terêsa, V. L. Carvalho, Ana M. Lobo, Paula S. Branco, Sundaresan Prabhakar

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

1-Aryl-2-acyl-2-cyanohydrazines undergo smooth thermal rearrangements to provide 2-aminoacylbenzimidazoles in excellent yields. A short synthesis of the highly mutagenic dietary amine, IQ, is reported.

Original languageEnglish
Pages (from-to)3115-3118
Number of pages4
JournalTetrahedron Letters
Volume38
Issue number17
DOIs
Publication statusPublished - 28 Apr 1997

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