Abstract
This invention provides an antibody or functional antibody fragments, or probe thereof directed against a unique group of antigens identified in cancer. The present invention comprises nucleotide sequences derived from L2A5 monoclonal antibody. The antibody or functional antibody fragment, or probe thereof includes a variable heavy chain domain and a variable light chain domain that has an amino acid sequence provided herein. This DNA/ amino acid sequence conjugation is unique and has never been described before. The present invention further provides antibody or functional antibody fragment or a conjugate or a recombinant protein useful in the detection, treatment and prevention of human disease, including cancer.
Translated title of the contribution | L2A5 ANTIBODY OR FUNCTIONAL FRAGMENT THEREOF AGAINST TUMOUR ANTIGENS |
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Original language | Chinese (Traditional) |
Patent number | CN113287018 |
IPC | G01N 33/ 574 A I |
Priority date | 17/01/19 |
Filing date | 25/09/20 |
Publication status | Published - 20 Aug 2021 |