Research output per year
Research output per year
Personal profile
Research interests
My work has been devoted primarily to research on molecular mechanisms of resistance to antimalarial drugs using classical genetics tools combined with new concepts and technologies of genomics and bioinformatics. More recently, I have focused on the application of genomics concepts for the discovery of new therapies and vaccines against tropical diseases. I have worked in partnership with institutions from countries where different tropical parasites are a substantial public health problem, including in Brazil, where I was a Visiting Professor between 2011 and 2016.
Education/Academic qualification
Genetics, Doctorate, Unravelling the genetics of resistance to quinoline-containing antimalarials in Plasmodium chabaudi, University of Edinburgh
Award Date: 15 Jun 2001
External positions
Assistant Professor, Universidade Federal de Goiás
2 Jan 2011 → 31 Dec 2016
Keywords
- L Education (General)
- RM Therapeutics. Pharmacology
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants
Ferreira, L. T., Cassiano, G. C., Alvarez, L. C. S., Okombo, J., Calit, J., Fontinha, D., Gil-Iturbe, E., Coyle, R., Andrade, C. H., Sunnerhagen, P., Bargieri, D. Y., Prudêncio, M., Quick, M., Cravo, P. V., Lee, M. C. S., Fidock, D. A. & Costa, F. T. M., 29 Oct 2024, In: PLoS Pathogens. 20, 10, 25 p., e1012627.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Downloads (Pure) -
Innovative Multistage ML-QSAR Models for Malaria: From Data to Discovery
Borba, J. V. B., Salazar-Alvarez, L. C., Ferreira, L. T., Silva-Mendonça, S., Silva, M. F. B. D., Sanches, I. H., Clementino, L. D. C., Magalhães, M. L., Rimoldi, A., Calit, J., Santana, S., Prudêncio, M., Cravo, P. V., Bargieri, D. Y., Cassiano, G. C., Costa, F. T. M. & Andrade, C. H., 8 Aug 2024, In: ACS Medicinal Chemistry Letters. 15, 8, p. 1386-1395 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)14 Downloads (Pure) -
Mutation in the 26S proteasome regulatory subunit rpn2 gene in Plasmodium falciparum confers resistance to artemisinin.
Gonçalves, A. F., Lima-Pinheiro, A., Teixeira, M., Cassiano, G. C., Cravo, P. & Ferreira, P. E., 2024, In: Frontiers in Cellular and Infection Microbiology. 14, 1342856.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)5 Downloads (Pure) -
Whole genome sequencing identifies novel mutations in malaria parasites resistant to artesunate (ATN) and to ATN + mefloquine combination
Cassiano, G. C., Martinelli, A., Mottin, M., Neves, B. J., Andrade, C. H., Ferreira, P. E. & Cravo, P., 2024, In: Frontiers in Cellular and Infection Microbiology. 14, 1353057.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)11 Downloads (Pure) -
Antimalarial and Cytotoxic Activity of Native Plants Used in Cabo Verde Traditional Medicine
Essoh, A. P., Cassiano, G. C., Mandim, F., Barros, L., Gomes, I., Medeiros, M. M., Moura, M., Cravo, P. V. L. & Romeiras, M. M., Feb 2023, In: Plants. 12, 4, 12 p., 963.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)34 Downloads (Pure)
Press/Media
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Summer Internships Ciência Viva 2022: high school students were scientists in the field of malaria for two weeks
Márcia Melo Medeiros, Gustavo Capatti Cassiano, Joana Marques & Pedro Vitor Lemos Cravo
12/09/22
1 Media contribution
Press/Media: Research