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Research Output at NOVA 2005 2019

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Article
2019
2 Citations (Scopus)
Rheumatoid Factor
Nanoconjugates
Antibodies
Gold
Nanoparticles
5 Citations (Scopus)
Ionic Liquids
Solubility
Amino Acids
Water
Pharmaceutical Preparations
3 Citations (Scopus)

GLUT1 and GLUT3 involvement in anthocyanin gastric transport- Nanobased targeted approach

Oliveira, H., Roma-Rodrigues, C., Santos, A., Veigas, B., Brás, N., Faria, A., Calhau, C., de Freitas, V., Baptista, P. V., Mateus, N., Fernandes, A. R. & Fernandes, I., 1 Dec 2019, In : Scientific Reports. 9, 1, 789.

Research output: Contribution to journalArticle

Open Access
Anthocyanins
Stomach
Glucosides
Glucose
Nanoparticles
6 Citations (Scopus)
Ionic Liquids
Drug Compounding
Ibuprofen
Salts
Pharmaceutical Preparations
1 Citation (Scopus)
Polyhydroxyalkanoates
Glycerol
Byproducts
Polymers
polymer
2 Citations (Scopus)

Structural aspects of a trimetallic Cu II derivative: cytotoxicity and anti-proliferative activity on human cancer cell lines

Das, K., Datta, A., Massera, C., Roma-Rodrigues, C., Barroso, M., Baptista, P. V. & Fernandes, A. R., 3 Apr 2019, In : Journal of Coordination Chemistry. 72, 5-7, p. 920-940 21 p.

Research output: Contribution to journalArticle

Cytotoxicity
cultured cells
cancer
Cells
Derivatives

Structural characterization and biological properties of silver(I) tris(pyrazolyl)methane sulfonate

Almeida, J., Roma-Rodrigues, C., Mahmoud, A. G., Guedes da Silva, M. F. C., Pombeiro, A. J. L., Martins, L. M. D. R. S., Baptista, P. V. & Fernandes, A. R., 1 Oct 2019, In : Journal of Inorganic Biochemistry. 199, 110789.

Research output: Contribution to journalArticle

Silver
Cells
B-Cell Lymphoma
Apoptosis
Fibroblasts
2018

A novel BCR-ABL1 mutation in a patient with philadelphia chromosome-positive B-cell acute lymphoblastic leukemia

Vinhas, R., Lourenço, A., Santos, S., Lemos, M., Ribeiro, P., de Sousa, A. B., Baptista, P. V. & Fernandes, A. R., 1 Jan 2018, In : OncoTargets and Therapy. 11, p. 8589-8598 10 p.

Research output: Contribution to journalArticle

Open Access
Chromosomes, Human, 4-5
Philadelphia Chromosome
Precursor Cell Lymphoblastic Leukemia-Lymphoma
B-Lymphocytes
Mutation
8 Citations (Scopus)
21 Downloads (Pure)

Combination of chemotherapy and Au-nanoparticle photothermy in the visible light to tackle doxorubicin resistance in cancer cells

Pedrosa, P., Mendes, R., Cabral, R., Martins, L. M. D. R. S., Baptista, P. V. & Fernandes, A. R., 1 Dec 2018, In : Scientific Reports. 8, 1, 11429.

Research output: Contribution to journalArticle

Open Access
File
Combination Drug Therapy
Nanoparticles
Doxorubicin
Light
Drug Therapy
8 Citations (Scopus)

Evaluation of cell toxicity and DNA and protein binding of green synthesized silver nanoparticles

Ribeiro, A. P. C., Anbu, S., Alegria, E. C. B. A., Fernandes, A. R., Baptista, P. V., Mendes, R., Matias, A. S., Mendes, M., Guedes da Silva, M. F. C. & Pombeiro, A. J. L., May 2018, In : Biomedicine and Pharmacotherapy. 101, p. 137-144 8 p.

Research output: Contribution to journalArticle

DNA-Binding Proteins
Silver
Nanoparticles
Inhibitory Concentration 50
Spectrum Analysis
3 Citations (Scopus)
1 Downloads (Pure)

Multifunctional microfluidic chip for optical nanoprobe based RNA detection - Application to Chronic Myeloid Leukemia

Alves, P. U., Vinhas, R., Fernandes, A. R., Birol, S. Z., Trabzon, L., Bernacka-Wojcik, I., Igreja, R., Lopes, P., Baptista, P. V., Águas, H., Fortunato, E. & Martins, R., 1 Dec 2018, In : Scientific Reports. 8, 1, 381.

Research output: Contribution to journalArticle

Open Access
File
Nanoprobes
Microfluidics
Screening
RNA
Gold
5 Citations (Scopus)

Nanoparticle-AntagoMIR based targeting of MIR-31 to induce osterix and osteocalcin expression in mesenchymal stem cells

McCully, M., Conde, J., Baptista, P. V., Mullin, M., Dalby, M. J. & Berry, C. C., 1 Feb 2018, In : PLoS ONE. 13, 2, e0192562.

Research output: Contribution to journalArticle

Open Access
File
osteocalcin
Regenerative Medicine
Osteocalcin
nanoparticles
Stem cells

Optical and Structural Characterization of a Chronic Myeloid Leukemia DNA Biosensor

Cordeiro, M., Otrelo-Cardoso, A. R. C., Svergun, D. I., Konarev, P. V., Lima, J. C., Santos-Silva, T. & Baptista, P. V., 18 May 2018, In : ACS Chemical Biology. 13, 5, p. 1235-1242 8 p.

Research output: Contribution to journalArticle

Open Access
Thermophoresis
Electrophoretic mobility
Biosensing Techniques
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
X ray scattering
4 Citations (Scopus)
5 Downloads (Pure)
Open Access
File
Dendrimers
Chemotherapy
Powders
Doxorubicin
Nanoparticles
3 Citations (Scopus)
6 Downloads (Pure)
Open Access
File
Cytotoxicity
cultured cells
deoxyribonucleic acid
Cells
evaluation
9 Citations (Scopus)

The Important Role of the Nuclearity, Rigidity, and Solubility of Phosphane Ligands in the Biological Activity of Gold(I) Complexes

Svahn, N., Moro, A. J., Roma-Rodrigues, C., Puttreddy, R., Rissanen, K., Baptista, P. V., Fernandes, A. R., Lima, J. C. & Rodríguez, L., 1 Oct 2018, In : Chemistry-A European Journal. 24, 55, p. 14654-14667 14 p.

Research output: Contribution to journalArticle

phosphine
Cytotoxicity
Bioactivity
Rigidity
Gold
2017
3 Citations (Scopus)

A digital microfluidics platform for loop-mediated isothermal amplification detection

Coelho, B. J., Veigas, B., Águas, H., Fortunato, E., Martins, R., Baptista, P. V. & Igreja, R., 16 Nov 2017, In : Sensors (Switzerland). 17, 11, 2616.

Research output: Contribution to journalArticle

Open Access
Digital microfluidics
Microfluidics
Amplification
platforms
Molecular Pathology
4 Citations (Scopus)

Allele specific LAMP- gold nanoparticle for characterization of single nucleotide polymorphisms

Carlos, F. F., Veigas, B., Matias, A. S., Doria, G., Flores, O. & Baptista, P. V., 1 Dec 2017, In : Biotechnology Reports. 16, p. 21-25 5 p.

Research output: Contribution to journalArticle

Gold
Nanoparticles
single nucleotide polymorphism
Single Nucleotide Polymorphism
Alleles
7 Citations (Scopus)

Gold nanobeacons for tracking gene silencing in zebrafish

Cordeiro, M., Carvalho, L., Silva, J., Saúde, L., Fernandes, A. R. & Baptista, P. V., 1 Jan 2017, In : Nanomaterials. 7, 1, 10.

Research output: Contribution to journalArticle

Gold
Genes
Fluorescence
Proteins
Zebrafish Proteins
9 Citations (Scopus)
Open Access
Nanoconjugates
Gene Silencing
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Gold
Protein-Tyrosine Kinases
3 Citations (Scopus)

Immortalization and characterization of a new canine mammary tumour cell line FR37-CMT

Raposo, L. R., Roma-Rodrigues, C., Faísca, P., Alves, M., Henriques, J., Carvalheiro, M. C., Corvo, M. L., Baptista, P. V., Pombeiro, A. J. & Fernandes, A. R., 1 Sep 2017, In : Veterinary and Comparative Oncology. 15, 3, p. 952-967 16 p.

Research output: Contribution to journalArticle

mammary neoplasms (animal)
Tumor Cell Line
Canidae
cell lines
Breast Neoplasms
24 Citations (Scopus)

Multifunctional gold-nanoparticles: A nanovectorization tool for the targeted delivery of novel chemotherapeutic agents

Fernandes, A. R., Jesus, J., Martins, P., Figueiredo, S., Rosa, D., Martins, L. M. R. D. R. S., Corvo, M. L., Carvalheiro, M. C., Costa, P. M. & Baptista, P. V., 10 Jan 2017, In : Journal Of Controlled Release. 245, p. 52-61 10 p.

Research output: Contribution to journalArticle

Open Access
Gold
Nanoparticles
Neoplasms
Epidermal Growth Factor Receptor
Heterografts
42 Citations (Scopus)
Open Access
Gold
Nanoparticles
Hot Temperature
Breast Neoplasms
Drug Therapy
7 Citations (Scopus)

Potentiating angiogenesis arrest in vivo via laser irradiation of peptide functionalised gold nanoparticles

Pedrosa, P., Heuer-Jungemann, A., Kanaras, A. G., Fernandes, A. R. & Baptista, P. V., 21 Nov 2017, In : Journal of Nanobiotechnology. 15, 1, 85.

Research output: Contribution to journalArticle

Open Access
Angiogenic Proteins
Blood vessels
Laser beam effects
Gold
Nanoparticles
5 Citations (Scopus)

Quantitative real-time monitoring of RCA amplification of cancer biomarkers mediated by a flexible ion sensitive platform

Veigas, B., Pinto, J., Vinhas, R., Calmeiro, T., Martins, R., Fortunato, E. & Baptista, P. V., 15 May 2017, In : Biosensors & Bioelectronics. 91, p. 788-795 8 p.

Research output: Contribution to journalArticle

Tumor Biomarkers
Amplification
RNA
Gene expression
Ions
18 Citations (Scopus)

Smuggling gold nanoparticles across cell types: A new role for exosomes in gene silencing

Roma-Rodrigues, C., Pereira, F., Alves De Matos, A. P., Fernandes, M., Baptista, P. V. & Fernandes, A. R., May 2017, In : Nanomedicine-Nanotechnology Biology And Medicine. 13, 4, p. 1389-1398 10 p.

Research output: Contribution to journalArticle

Open Access
Exosomes
Gene Silencing
Gold
Nanoparticles
Genes
3 Citations (Scopus)

Targeting canine mammary tumours via gold nanoparticles functionalized with promising Co(II) and Zn(II) compounds

Raposo, L. R., Roma-Rodrigues, C., Jesus, J., Martins, L. M. D. R. S., Pombeiro, A. J. L., Baptista, P. V. & Fernandes, A. R., 2017, (Accepted/In press) In : Veterinary and Comparative Oncology. 15, 4, p. 1537-1542

Research output: Contribution to journalArticle

mammary neoplasms (animal)
Gold
Nanoparticles
Canidae
Breast Neoplasms
2016
4 Citations (Scopus)
1 Downloads (Pure)
Open Access
File
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Gold
Molecular Pathology
Energy Transfer
Technology
9 Citations (Scopus)

Colorimetric assessment of BCR-ABL1 transcripts in clinical samples via gold nanoprobes

Vinhas, R., Correia, C., Ribeiro, P., Lourenco, A., de Sousa, A. B., Fernandes, M. A. N. D. C. R. & Baptista, P. M. R. V., Jul 2016, In : Analytical and Bioanalytical Chemistry. 408, 19, p. 5277-5284 8 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Heteroleptic mononuclear compounds of ruthenium(II): Synthesis, structural analyses, in vitro antitumor activity and in vivo toxicity on zebrafish embryos

Lenis-rojas, O. A., Fernandes, A. R., Roma-Rodrigues, C., Baptista, P. V., Marques, F., Pérez-fernández, D., Guerra-varela, J., Sánchez-Magraner, L., Vázquez-garcía, D., Torres, M. L., Fernández-Planells, A. & Fernández-Rosas, J., 21 Dec 2016, In : Dalton Transactions. 45, 47, p. 19127-19140

Research output: Contribution to journalArticle

Open Access
Ruthenium Compounds
Zebrafish
Embryonic Structures
DNA
HCT116 Cells
4 Citations (Scopus)

Infection of human keratinocytes by Streptococcus dysgalactiae subspecies dysgalactiae isolated from milk of the bovine udder

Roma-Rodrigues, C., Alves-Barroco, C., Raposo, L. R., Costa, M. N., Fortunato, E., Baptista, P. M. R. V., Fernandes, M. A. N. D. C. R. & Santos-Sanches, I., 1 Apr 2016, In : Microbes And Infection. 18, 4, p. 290-293 4 p.

Research output: Contribution to journalArticle

Open Access
15 Citations (Scopus)

In vitro and in vivo biological characterization of the anti-proliferative potential of a cyclic trinuclear organotin(IV) complex

Martins, M., Baptista, PV., Mendo, A. S., Correia, C., Videira, P., Rodrigues, AS., Muthukumaran, J., Santos-Silva, T., Silva, A., Guedes da Silva, M. F. C., Gigante, J., Duarte, A., Gajewska, M. & Fernandes, AR., 2016, In : Molecular Biosystems. 12, 3, p. 1015-1023 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Liposomes as Delivery System of a Sn(IV) Complex for Cancer Therapy

Luisa Corvo, M., Mendo, A. S., Figueiredo, S., Gaspar, R., Larguinho, M., Guedes da Silva, M. F. C., Baptista, P. M. R. V. & Fernandes, M. A. N. D. C. R., Jun 2016, In : Pharmaceutical Research. 33, 6, p. 1351-1358 8 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Peptide-coated gold nanoparticles for modulation of angiogenesis in vivo

Roma-Rodrigues, C., Heuer-Jungemann, A., Fernandes, M. A. N. D. C. R., Kanaras, A. G. & Baptista, P. M. R. V., 2016, In : International journal of nanomedicine. 11, p. 2633-2639 7 p.

Research output: Contribution to journalArticle

Open Access
24 Citations (Scopus)

Synthesis, characterization, thermal properties and antiproliferative potential of copper(II) 4 '-phenylterpyridine compounds

Ma, Z., Zhang, B., Guedes da Silva, M. F. C., Silva, J., Mendo, A. S., Baptista, P. M. R. V., Fernandes, M. A. N. D. C. R. & Pombeiro, A. J. L., 2016, In : Dalton Transactions. 45, 12, p. 5339-5355 17 p.

Research output: Contribution to journalArticle

2015
11 Citations (Scopus)

Characterization of antiproliferative potential and biological targets of a copper compound containing 4'-phenyl terpyridine

Mendo, A. S., Figueiredo, S., Roma-Rodrigues, C., Videira, P. A., Ma, Z., Diniz, M., Larguinho, M., Costa, P. M., Lima, J. C., Pombeiro, A. J. L., Baptista, P. V. & Fernandes, A. R., Sep 2015, In : Journal Of Biological Inorganic Chemistry. 20, 6, p. 935-948 14 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

DNA adduct identification using gold-aptamer nanoprobes

Larguinho, M., Santos, S., Almeida, J. & Baptista, P., Apr 2015, In : Iet Nanobiotechnology. 9, 2, p. 95-101 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Gold nanoparticle-siRNA mediated oncogene knockdown at RNA and protein level, with associated gene effects

Child, H. W., Hernandez, Y., Conde, J., Mullin, M., Baptista, P., Maria de la Fuente, J. & Berry, C. C., 2015, In : Nanomedicine. 10, 16, p. 2513-2525 13 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

One nanoprobe, two pathogens: gold nanoprobes multiplexing for point-of-care

Veigas, B., Pedrosa, P., Carlos, F. F., Mancio-Silva, L., Grosso, A. R., Fortunato, E., Mota, M. M. & Baptista, P., 7 Aug 2015, In : Journal of Nanobiotechnology. 13, 1, 7 p., 48.

Research output: Contribution to journalArticle

14 Citations (Scopus)

POxylated Polyurea Dendrimers: Smart Core-Shell Vectors with IC50 Lowering Capacity

Restani, R. B., Conde, J., Pires, R. F., Martins, P., Fernandes, M. A. N. D. C. R., Baptista, P. M. R. V., Bonifacio, V. D. B. & Ricardo, A. I. N. M. A. D. O., Aug 2015, In : Macromolecular Bioscience. 15, 8, p. 1045-1051 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

RNAi-based glyconanoparticles trigger apoptotic pathways for in vitro and in vivo enhanced cancer-cell killing

Conde, J., Tian, F., Hernandez, Y., Bao, C., Baptista, P. M. R. V., Cui, D., Stoeger, T. & de la Fuente, J. M., 2015, In : Nanoscale. 7, 19, p. 9083-9091 9 p.

Research output: Contribution to journalArticle

Scalable approach for the production of functional DNA based gold nanoprobes

Veigas, B., Portugal, C., Valerio, R., Fortunato, E., Crespo, J. G. & Baptista, P., 15 Oct 2015, In : Journal of Membrane Science. 492, p. 528-535 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Significance of the balance between intracellular glutathione and polyethylene glycol for successful release of small interfering RNA from gold nanoparticles

McCully, M., Hernandez, Y., Conde, J., Baptista, P. M. R. V., de la Fuente, J. M., Hursthouse, A., Stirling, D. & Berry, C. C., Oct 2015, In : Nano Research. 8, 10, p. 3281-3292 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Single Nucleotide Polymorphism Detection Using Gold Nanoprobes and Bio-Microfluidic Platform With Embedded Microlenses

Bernacka-Wojcik, I., Aguas, H., Carlos, F. F., Lopes, P., Wojcik, P. J., Costa, M. N., Veigas, B., Igreja, R., Fortunato, E., Baptista, P. & Martins, R., 10 Mar 2015, In : Biotechnology and Bioengineering. 112, 6, p. 1210-1219 10 p.

Research output: Contribution to journalArticle

2014
96 Citations (Scopus)
Open Access
67 Citations (Scopus)

Antibody-drug gold nanoantennas with Raman spectroscopic fingerprints for in vivo tumour theranostics

Conde, J., Bao, C., Cui, D., Baptista, P. & Tian, F., 10 Jun 2014, In : Journal Of Controlled Release. 183, p. 87-93 7 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

A promising road with challenges: where are gold nanoparticles in translational research?

Bao, C., Conde, J., Polo, E., del Pino, P., Moros, M., Baptista, P., Grazu, V., Cui, D. & de la Fuente, J. M., 2014, In : Nanomedicine. 9, 15, p. 2353-2370 18 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Characterization of genomic single nucleotide polymorphism via colorimetric detection using a single gold nanoprobe

Carlos, F. F., Flores, O., Doria, G. & Baptista, P., 15 Nov 2014, In : Analytical Biochemistry. 465, p. 1-5 5 p.

Research output: Contribution to journalArticle