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Pedro Miguel Ribeiro Viana Baptista

Professor

Former affiliation
 https://orcid.org/0000-0001-5255-7095
  • 4535 Citations
  • 35 h-Index
20052019
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Personal profile

Research interests

(Nano)Theranostics effectively brings together diagnostics and therapeutics onto a single platform making them powerful tools in biomedicine. This even more so when using nanoscale structures, whose optical, (eletro)chemical and biological properties make them optimal biosensing transducers for theranostics agents. When designing a nanotheranostics, one should take into consideration:

  1. the choice of most suitable nanocarrier for effective delivery for tissue delivery and cell internalization;
  2. the effector molecule, from standard drugs to nucleic acids;
  3. to ensure controlled release of effector molecule;
  4. the signal  transducer (e.g. imaging) component that allows for the real time monitoring of the nanoconjugate location and effect on target tissue cells;
  5. an active targeting agent, typically a cell-surface marker or an oligonucleotide, that maximizes specificity of the vector and minimizes damages to healthy cells.

Nanomedicine@FCT aims to highlight recent advances in the development of novel biosensing schemes and strategies that potentiate and enhance the performance of (nano)theranostics applications with a strong focus on those suitable for translation to the clinics.

Keywords: Nanomedicine; Cancer; Human Molecular Genetics; Nanoparticles; Diagnostics; Therapeutics; Gene silencing

Fingerprint Dive into the research topics where Pedro Miguel Ribeiro Viana Baptista is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Research Output at NOVA 2005 2019

1 Citation (Scopus)

Antibody modified gold nanoparticles for fast colorimetric screening of rheumatoid arthritis

Veigas, B., Matias, A., Calmeiro, T., Fortunato, E., Fernandes, A. R. & Baptista, P. V., 7 Jun 2019, In : Analyst. 144, 11, p. 3613-3619 7 p.

Research output: Contribution to journal › Article

Rheumatoid Factor
Nanoconjugates
Antibodies
Gold
Nanoparticles

Cation-mediated gelation of the fucose-rich polysaccharide FucoPol: preparation and characterization of hydrogel beads and their cytotoxicity assessment

Fialho, L., Araújo, D., Alves, V. D., Roma-Rodrigues, C., Baptista, P. V., Fernandes, A. R., Freitas, F. & Reis, M. A. M., 1 Jan 2019, In : International Journal of Polymeric Materials and Polymeric Biomaterials.

Research output: Contribution to journal › Article

Fucose
Hydrogel
Gelation
Cytotoxicity
Polysaccharides
5 Citations (Scopus)

Enhancement of water solubility of poorly water-soluble drugs by new biocompatible N-acetyl amino acid N-alkyl cholinium-based ionic liquids

Jesus, A. R., Soromenho, M. R. C., Raposo, L. R., Esperança, J. M. S. S., Baptista, P. V., Fernandes, A. R. & Reis, P. M., 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 137, p. 227–232

Research output: Contribution to journal › Article

Ionic Liquids
Solubility
Amino Acids
Water
Pharmaceutical Preparations
1 Citation (Scopus)

GLUT1 and GLUT3 involvement in anthocyanin gastric transport- Nanobased targeted approach

Oliveira, H., Roma-Rodrigues, C., Santos, A., Veigas, B., Brás, N., Faria, A., Calhau, C., de Freitas, V., Baptista, P. V., Mateus, N., Fernandes, A. R. & Fernandes, I., 1 Dec 2019, In : Scientific Reports. 9, 1, 789.

Research output: Contribution to journal › Article

Open Access
Anthocyanins
Stomach
Glucosides
Glucose
Nanoparticles
4 Citations (Scopus)

Ionic Liquids and Salts from Ibuprofen as Promising Innovative Formulations of an Old Drug

Santos, M. M., Raposo, L. R., Carrera, G. V. S. M., Costa, A., Dionísio, M., Baptista, P. V., Fernandes, A. R. & Branco, L. C., 6 May 2019, In : Chemmedchem. 14, 9

Research output: Contribution to journal › Article

Ionic Liquids
Drug Compounding
Ibuprofen
Salts
Pharmaceutical Preparations