Research output per year
Research output per year
Personal profile
Research interests
(Nano)Theranostics effectively brings together diagnostics and therapeutics onto a single platform making them powerful tools in biomedicine. This even more so when using nanoscale structures, whose optical, (eletro)chemical and biological properties make them optimal biosensing transducers for theranostics agents. When designing a nanotheranostics, one should take into consideration:
- the choice of most suitable nanocarrier for effective delivery for tissue delivery and cell internalization;
- the effector molecule, from standard drugs to nucleic acids;
- to ensure controlled release of effector molecule;
- the signal transducer (e.g. imaging) component that allows for the real time monitoring of the nanoconjugate location and effect on target tissue cells;
- an active targeting agent, typically a cell-surface marker or an oligonucleotide, that maximizes specificity of the vector and minimizes damages to healthy cells.
Nanomedicine@FCT aims to highlight recent advances in the development of novel biosensing schemes and strategies that potentiate and enhance the performance of (nano)theranostics applications with a strong focus on those suitable for translation to the clinics.
Keywords: Nanomedicine; Cancer; Human Molecular Genetics; Nanoparticles; Diagnostics; Therapeutics; Gene silencing
Education/Academic qualification
Biotechnology, Doctorate, University of London
Award Date: 1 Jan 2001
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Research output
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A solvent‐free strategy to prepare amorphous salts of folic acid with enhanced solubility and cell permeability
Martins, I. C. B., Forte, A., Diogo, H. P., Raposo, L. R., Baptista, P. V., Fernandes, A. R., Branco, L. C. & Duarte, M. T., 2022, In: Chemistry–Methods. 2, 6, 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Digital Microfluidics-Powered Real-Time Monitoring of Isothermal DNA Amplification of Cancer Biomarker
Coelho, B. J., Veigas, B., Bettencourt, L., Águas, H., Fortunato, E., Martins, R., Baptista, P. V. & Igreja, R., 28 Mar 2022, In: Biosensors. 12, 4, 12 p., 201.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)1 Downloads (Pure) -
Endogenous Fluorescent Proteins in the Mucus of an Intertidal Polychaeta: Clues for Biotechnology
Rodrigo, A. P., Lopes, A. C., Pereira, R., Anjo, S. I., Manadas, B., Grosso, A. R., Baptista, P. V., Fernandes, A. R. & Costa, P. M., 25 Mar 2022, In: Marine Drugs. 20, 4, 19 p., 224.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Engineering gold nanoparticles for molecular diagnostics and biosensing
Oliveira, B. B., Ferreira, D., Fernandes, A. R. & Baptista, P. V., 5 Aug 2022, (E-pub ahead of print) In: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 28 p., e1836.Research output: Contribution to journal › Review article › peer-review
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Light Triggered Enhancement of Antibiotic Efficacy in Biofilm Elimination Mediated by Gold-Silver Alloy Nanoparticles
Alves-Barroco, C., Rivas-García, L., Fernandes, A. R. & Baptista, P. V., 28 Feb 2022, In: Frontiers in Microbiology. 13, p. 1-15 15 p., 841124.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)1 Downloads (Pure)
Prizes
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GILEAD Award - Aplicação de nanopartículas superparamagnéticas no diagnostico rápido, simultâneo e não invasivo da infeção pelo VIH e da tuberculose
Machado, Diana Isabel Oliveira (Recipient), Viveiros, Miguel (Recipient), Piedade, João Mário Brás da (Recipient) & Baptista, Pedro Miguel Ribeiro Viana (Recipient), 2018
Prize: Prize (including medals and awards)
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Merit Award for Best Panel Communication - “Cell and Tissue Engineering, Biomaterials and Nanobiotechnologies”
Veigas, B. (Recipient), Perdigão , J. (Recipient), Portugal, I. (Recipient), Couto, Isabel Maria dos Santos Leitão (Recipient), Viveiros, Miguel (Recipient) & Baptista, Pedro Miguel Ribeiro Viana (Recipient), 2009
Prize: Prize (including medals and awards)
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Merit Award Santander/Totta 2012 - "NanoTB - Nanodiagnostics for XDRTB at point-of-need"
Viveiros, Miguel (Recipient), Baptista, Pedro Miguel Ribeiro Viana (Recipient) & Couto, Isabel Maria dos Santos Leitão (Recipient), 2012
Prize: Prize (including medals and awards)