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Personal profile

Education/Academic qualification

Biomedicine, Doctorate

External positions

Visting Professor, University College London

1 Jun 2016 → …

Keywords

  • R Medicine (General)

Fingerprint Dive into the research topics where Miguel Seabra is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Choroideremia Medicine & Life Sciences
Melanosomes Medicine & Life Sciences
rab GTP-Binding Proteins Medicine & Life Sciences
Prenylation Medicine & Life Sciences
Proteins Medicine & Life Sciences
Retinal Pigment Epithelium Medicine & Life Sciences
Melanocytes Medicine & Life Sciences
Membranes Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output at NOVA 2007 2019

1 Citation (Scopus)

Dual chemical probes enable quantitative system-wide analysis of protein prenylation and prenylation dynamics

Storck, E. M., Morales-Sanfrutos, J., Serwa, R. A., Panyain, N., Lanyon-Hogg, T., Tolmachova, T., Ventimiglia, L. N., Martin-Serrano, J., Seabra, M. C., Wojciak-Stothard, B. & Tate, E. W., Jun 2019, In : Nature Chemistry. 11, 6, p. 552-561 10 p.

Research output: Contribution to journalArticle

Proteins
Dimethylallyltranstransferase
Cells
Terpenes
Proteome

Melanin processing by keratinocytes: A non-microbial type of host-pathogen interaction?

Moreiras, H., Lopes-da-Silva, M., Seabra, M. C. & Barral, D. C., 1 Apr 2019, In : Traffic. 20, 4, p. 301-304 4 p.

Research output: Contribution to journalComment/debate

Host-Pathogen Interactions
Melanins
Pathogens
Keratinocytes
Skin Pigmentation

Nucleotide exchange factor Rab3GEP requires DENN and non-DENN elements for activation and targeting of rab27a

Sanza, P., Evans, R. D., Briggs, D. A., Cantero, M., Montoliu, L., Patel, S., Sviderskaya, E. V., Itzen, A., Figueiredo, A. C., Seabra, M. C. & Hume, A. N., 1 May 2019, In : Journal Of Cell Science. 132, 9, jcs212035.

Research output: Contribution to journalArticle

Open Access
File
Guanosine Triphosphate
Nucleotides
Melanosomes
Melanocytes
Membranes
1 Citation (Scopus)
1 Downloads (Pure)

Remodeling of the Basal Labyrinth of Retinal Pigment Epithelial Cells With Osmotic Challenge, Age, and Disease

Hayes, M. J., Burgoyne, T., Wavre-Shapton, S. T., Tolmachova, T., Seabra, M. C. & Futter, C. E., 3 Jun 2019, In : Investigative ophthalmology & visual science. 60, 7, p. 2515-2524 10 p.

Research output: Contribution to journalArticle

Open Access
File
Retinal Pigments
Inner Ear
Retinal Pigment Epithelium
Epithelial Cells
Choroideremia
14 Citations (Scopus)

Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia

Xue, K., Jolly, J. K., Barnard, A. R., Rudenko, A., Salvetti, A. P., Patrício, M. I., Edwards, T. L., Groppe, M., Orlans, H. O., Tolmachova, T., Black, G. C., Webster, A. R., Lotery, A. J., Holder, G. E., Downes, S. M., Seabra, M. C. & MacLaren, R. E., 1 Oct 2018, In : Palliative medicine. 24, 10, p. 1507-1512 6 p.

Research output: Contribution to journalLetter

Choroideremia
Genetic Therapy
Visual Acuity
Blindness
Patient Acuity