• 1026 Citations
  • 19 h-Index
19982020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output at NOVA

Filter
Article
2020

Virtual genetic diagnosis for familial hypercholesterolemia powered by machine learning

Pina, A., Helgadottir, S., Mancina, R. M., Pavanello, C., Pirazzi, C., Montalcini, T., Henriques, R., Calabresi, L., Wiklund, O., Macedo, M. P., Valenti, L., Volpe, G. & Romeo, S., 2020, In : European Journal of Preventive Cardiology.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2019

27th Annual Meeting of the European Group for the study of Insulin Resistance, Lisbon, Portugal, 8-9th May 2019

Bonner, C., Jones, J., Paula Macedo, M. & Gastaldelli, A., Sep 2019, In : Cardiovascular endocrinology & metabolism. 8, 3, p. 88-89 2 p.

Research output: Contribution to journalArticle

2-Deoxyglycosylation towards more effective and bioavailable neuroprotective molecules inspired by nature

Dias, C., Matos, A. M., Blásquez-Sanchez, M. T., Calado, P., Martins, A., Dätwyler, P., Ernst, B., Macedo, M. P., Colabufo, N. & Rauter, A. P., Jul 2019, In : Pure and Applied Chemistry. 91, 7, p. 1209-1221

Research output: Contribution to journalArticle

Data on metabolic profile of insulin-degrading enzyme knockout mice

Borges, D. O., Meneses, M. J., Dias, T. R., Martins, F. O., Oliveira, P. F., Alves, M. G. & Macedo, M. P., 1 Aug 2019, In : Data in brief. 25, 104023.

Research output: Contribution to journalArticle

Open Access
File
5 Downloads (Pure)

Design and Synthesis of CNb-targeted Flavones and Analogues with Neuroprotective Potential Against H2O2- and Aβ1-42-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells

Matos, A. M. D., Martins, A., Man, T., Evans, D., Walter, M., Oliveira, M. C., López, Ó., Fernandez-Bolaños, J. G., Dätwyler, P., Ernst, B., Macedo, M. P., Contino, M., Colabufo, N. A. & Rauter, A. P., 1 Jun 2019, In : Pharmaceuticals. 12, 2, 98.

Research output: Contribution to journalArticle

Open Access
File

Determining contributions of exogenous glucose and fructose to de novo fatty acid and glycerol synthesis in liver and adipose tissue

Silva, J. C. P., Marques, C., Martins, F. O., Viegas, I., Tavares, L., Macedo, M. P. & Jones, J. G., 1 Dec 2019, In : Metabolic Engineering. 56, p. 69-76 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Knockout of insulin-degrading enzyme leads to mice testicular morphological changes and impaired sperm quality

Meneses, M. J., Borges, D. O., Dias, T. R., Martins, F. O., Oliveira, P. F., Macedo, M. P. & Alves, M. G., Apr 2019, In : Molecular and Cellular Endocrinology. 486, p. 11-17

Research output: Contribution to journalArticle

2 Citations (Scopus)
2 Citations (Scopus)

Transfer of glucose hydrogens via acetyl-CoA, malonyl-CoA, and NADPH to fatty acids during de novo lipogenesis

Belew, G. D., Silva, J., Rito, J., Tavares, L., Viegas, I., Teixeira, J., Oliveira, P. J., Macedo, M. P. & Jones, J. G., 1 Dec 2019, In : Journal Of Lipid Research. 60, 12, p. 2050-2056 7 p.

Research output: Contribution to journalArticle

Dipeptidyl Peptidase-4 Is a Pro-Recovery Mediator During Acute Hepatotoxic Damage and Mirrors Severe Shifts in Kupffer Cells

Duarte, N., Coelho, I., Holovanchuk, D., Inês Almeida, J., Penha-Gonçalves, C. & Paula Macedo, M., Sep 2018, In : Hepatology communications. 2, 9, p. 1080-1094 15 p.

Research output: Contribution to journalArticle

Open Access
File
1 Downloads (Pure)

Rho-kinase/AMPK axis regulates hepatic lipogenesis during overnutrition

Huang, H., Lee, S. H., Sousa-Lima, I., Kim, S. S., Hwang, W. M., Dagon, Y., Yang, W. M., Cho, S., Kang, M. C., Seo, J. A., Shibata, M., Cho, H., Belew, G. D., Bhin, J., Desai, B. N., Ryu, M. J., Shong, M., Li, P., Meng, H., Chung, B. H. & 7 others, Hwang, D., Kim, M. S., Park, K. S., Macedo, M. P., White, M., Jones, J. & Kim, Y. B., 3 Dec 2018, In : Journal of Clinical Investigation. 128, 12, p. 5335-5350 16 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
4 Downloads (Pure)
2017

Genetic control of glucose tolerance and insulin secretion by CD26/DPP4 is abrogated in prediabetes

Patarrao, R. S., Duarte, N., Raposo, J. F., Costa, J., Ribeiro, R. T., Gardete-Correia, L., Duarte, R., Boavida, J. M., Correia, I., Andrade, R., Medina, J., Penha-Goncalves, C. & Macedo, M. P., Sep 2017, In : Diabetologia. 60, p. S176-S176 1 p.

Research output: Contribution to journalArticle

Mutant A53T α-Synuclein Improves Rotarod Performance Before Motor Deficits and Affects Metabolic Pathways

Guerreiro, P. S., Coelho, J. E., Sousa-Lima, I., Macedo, M. P., Lopes, L. V., Outeiro, T. F. & Pais, T. F., 1 Mar 2017, In : NeuroMolecular Medicine. 19, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2016

Diabetes hinders community-acquired pneumonia outcomes in hospitalized patients

Martins, M., Boavida, J. M., Raposo, J. F., Froes, F., Nunes, B., Ribeiro, R. T., Macedo, M. P. & Penha-Goncalves, C., Feb 2016, In : BMJ OPEN DIABETES RESEARCH CARE. 4, 1, e000181.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Direct analysis of [6,6-H-2(2)]glucose and [U-C-13(6)]glucose dry blood spot enrichments by LC-MS/MS

Coelho, M., Mendes, V. M., Lima, I. S., Martins, F. O., Fernandes, A. B., Macedo, M. P., Jones, J. G. & Manadas, B., 1 Jun 2016, In : Journal of Chromatography B. 1022, p. 242-248 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
20 Citations (Scopus)

Inside the Diabetic Brain: Role of Different Players Involved in Cognitive Decline

Gaspar, J. M., Baptista, F. I., Macedo, M. P. & Ambrosio, A. F., Feb 2016, In : Acs Chemical Neuroscience. 7, 2, p. 131-142 12 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Liver-specific deletion of ROCK1 prevents hepatic steatosis in leptin-deficient ob/ob mice

Lima, I. S., Lee, J. S. H., Huang, H., Chung, M., Macedo, M. P. & Kim, Y-T. Y-B. B. T., Aug 2016, In : Diabetologia. 59, p. S308-S308 1 p.

Research output: Contribution to journalArticle

Mechanisms by which the thiazolidinedione troglitazone protects against sucrose-induced hepatic fat accumulation and hyperinsulinaemia

Martins, F. P. D. C. O., Delgado, T. C., Viegas, J., Gaspar, J. M., Scott, D. K., O'Doherty, R. M., Macedo, M. P. & Jones, J. G., Jan 2016, In : British Journal of Pharmacology. 173, 2, p. 267-278 12 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Methylsulfonylmethane (MSM), an organosulfur compound, is effective against obesity-induced metabolic disorders in mice

Lima, I. S., Park, S-Y., Chung, M., Jung, H. J., Kang, M-C. C., Gaspar, J. M., Seo, J. A., Macedo, M. P., Park, K. S., Mantzoros, C., Lee, S-H. & Kim, Y-T. Y-B. B. T., Oct 2016, In : Metabolism-Clinical And Experimental. 65, 10, p. 1508-1521 14 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2015

Acute glucagon induces postprandial peripheral insulin resistance

Patarrão, R. S. & Macedo, M. P., 1 Jan 2015, In : PLoS ONE. 10, 5, p. Online

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
3 Downloads (Pure)

Mechanisms through which a small protein and lipid preload improves glucose tolerance

Macedo, M. P., Nov 2015, In : Diabetologia. 58, 11, p. 2503-2512

Research output: Contribution to journalArticle

17 Citations (Scopus)
2014

Exploiting the Therapeutic Potential of 8-beta-D-Glucopyranosylgenistein: Synthesis, Antidiabetic Activity, and Molecular Interaction with Islet Amyloid Polypeptide and Amyloid beta-Peptide (1-42)

Jesus, A. R., Dias, C., Matos, A. M., de Almeida, R. F. M., Viana, A. S., Marcelo, F. M. B. M., Ribeiro, R. T., Macedo, M. P., Airoldi, C., Nicotra, F., Martins, A., Cabrita, E. J., Jimenez-Barbere, J. & Rauter, A. P., 27 Nov 2014, In : Journal Of Medicinal Chemistry. 57, 22, p. 9463-9472 10 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

NOS2 variants reveal a dual genetic control of nitric oxide levels, susceptibility to Plasmodium infection, and cerebral malaria

de Jesus Trovoada, M., Martins, M., Mansour, R. B., Do Rosário Sambo, M., Fernandes, A. B., Gonçalves, L. A., Borja, A., Moya, R., Almeida, P., Costa, J., Marques, I., Paula Macedo, M., Coutinho, A., Narum, D. L. & Penha-Gonçalves, C., 1 Mar 2014, In : Infection and Immunity. 82, 3, p. 1287-1295 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2013
8 Citations (Scopus)
Open Access
File
26 Citations (Scopus)
2 Downloads (Pure)
9 Citations (Scopus)
9 Citations (Scopus)
20 Citations (Scopus)
2012
4 Citations (Scopus)
6 Citations (Scopus)
3 Citations (Scopus)
2010

High-fat diet results in postprandial insulin resistance that involves parasympathetic dysfunction

Afonso, R. A., Lautt, W. W., Schafer, J., Legare, D. J., Oliveira, A. G. & Macedo, M. P., 1 Jan 2010, In : British Journal Of Nutrition. 104, 10, p. 1450-1459

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
6 Downloads (Pure)
22 Citations (Scopus)
2007
9 Citations (Scopus)
11 Citations (Scopus)
5 Citations (Scopus)
2006
29 Citations (Scopus)
27 Citations (Scopus)
2 Citations (Scopus)

Meal-induced insulin sensitization in conscious and anaesthetized rat models comparing liquid mixed meal with glucose and sucrose

Sadri, P., Reid, M. A. G., Afonso, R. A., Schafer, J., Legare, D. J., Macedo, M. P. & Lautt, W. W., Feb 2006, In : British Journal Of Nutrition. 95, 2, p. 288-295 8 p.

Research output: Contribution to journalArticle

Open Access
File
22 Citations (Scopus)
5 Downloads (Pure)
2005
52 Citations (Scopus)