• FCT-NOVA, Campus Caparica, Unidade de Ciências Biomoleculares Aplicadas (UCIBIO)

    2829-516 Caparica

  • FCT-NOVA, Faculdade de Ciências e Tecnologia, Campus Caparica, Departamento de Química

    2829-516 Caparica

    Portugal

Accepting PhD Students

  • 5367 Citations
  • 40 h-Index
1993 …2020
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Research Output at NOVA 1993 2020

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Review article
Review article
7 Citations (Scopus)

Critical overview on the structure and metabolism of human aldehyde oxidase and its role in pharmacokinetics

Mota, C., Coelho, C., Leimkühler, S., Garattini, E., Terao, M., Santos-Silva, T. & Romão, M. J., 1 Aug 2018, In : Coordination Chemistry Reviews. 368, p. 35-59 25 p.

Research output: Contribution to journalReview article

Aldehyde Oxidase
Pharmacokinetics
oxidase
metabolism
Aldehydes
182 Citations (Scopus)

Mammalian molybdo-flavoenzymes, an expanding family of proteins: structure, genetics, regulation, function and pathophysiology

Garattini, E., Mendel, R., Romão, M. J., Wright, R. & Terao, M., 15 May 2003, In : Biochemical Journal. 372, 1, p. 15-32 18 p.

Research output: Contribution to journalReview article

Aldehyde Oxidase
Genetic Structures
Xanthine Dehydrogenase
Genes
Enzymes
79 Citations (Scopus)

Molybdenum and tungsten enzymes: the xanthine oxidase family

Brondino, C. D., Romão, M. J., Moura, I. & Moura, J. J. G., 1 Apr 2006, In : Current Opinion in Chemical Biology. 10, 2, p. 109-114 6 p.

Research output: Contribution to journalReview article

Tungsten
Molybdenum
Xanthine Oxidase
Catalytic Domain
Enzymes
11 Citations (Scopus)

Molybdenum enzymes in reactions involving aldehydes and acids.

Romão, M. J., Cunha, C. A., Brondino, C. D. & Moura, J. J. G., 1 Jan 2002, In : Metal ions in biological systems. 39, p. 539-570 32 p.

Research output: Contribution to journalReview article

16 Citations (Scopus)

Structural and mechanistic insights on nitrate reductases

Coelho, C. M. C. & Romão, M. J., 1 Dec 2015, In : Protein Science. 24, 12, p. 1901-1911 11 p.

Research output: Contribution to journalReview article

Nitrate Reductases
Crystal structure
Desulfovibrio desulfuricans
Nitrogen Cycle
Enzymes
11 Citations (Scopus)

Structural basis for the role of mammalian aldehyde oxidases in the metabolism of drugs and xenobiotics

Romão, M. J., Coelho, C., Santos-Silva, T., Foti, A., Terao, M., Garattini, E. & Leimkühler, S., 1 Apr 2017, In : Current Opinion in Chemical Biology. 37, p. 39-47 9 p.

Research output: Contribution to journalReview article

Aldehyde Oxidase
Xenobiotics
Metabolism
Pharmaceutical Preparations
Isoenzymes

Structure and function of the xanthine-oxidase family of molybdenum enzymes

Romao, M. J. & Huber, R., 1998, In : METAL SITES IN PROTEINS AND MODELS. 90, p. 69-95

Research output: Contribution to journalReview article

23 Citations (Scopus)
Aldehyde Oxidoreductases
Desulfovibrio gigas
Molybdenum
Xanthine Oxidase
Sulfur
22 Citations (Scopus)

X-ray crystallography in drug discovery

Carvalho, A. L., Trincão, J. & Romão, M. J., 1 Jan 2009, In : Methods In Molecular Biology (Clifton, N.J.). 572, p. 31-56 26 p.

Research output: Contribution to journalReview article

X Ray Crystallography
Drug Discovery
Ligands
Proteins
Drug Design