Personal profile
Research interests
Since my Ph.D. thesis my work has focused on the study of the mechanisms responsible for the emergence of drug resistance in bacteria, namely the contribution of efflux pumps. In particular, I have studied the contribution of efflux pumps in the development of drug resistance in Mycobacterium tuberculosis and other mycobacteria. Moreover, I was involved in the development of methods that allow the detection of efflux activity in bacteria and the in vitro testing of efflux inhibitors. I am also interested in the identification of new drugs, or adjuvants of already existent anti-tuberculosis drugs, that may be used as new therapeutical approaches. From 2011 to 2016, I worked as a post-doctoral researcher at the University of Zaragoza in Spain and was involved in the FP7 project More Medicines for Tuberculosis. Presently, I’m a Marie Curie Fellow (H2020-MSCA-IF-2017: iCHEMGENODRUGS_TB) at GHTM and my main research interest is to explore the novel concepts of drug repurposing and comparative chemogenomics to find new drugs against tuberculosis.
Fingerprint
- 1 Similar Profiles
-
Evaluation of Amlodipine and Imipramine Efficacy to Treat Galleria mellonella Infection by Biofilm-Producing and Antimicrobial-Resistant Staphylococcus aureus
Andrade, M., Neves, J., Bento, M., Marques, J., Seabra, S. G., Silveira, H., Rodrigues, L., Armada, A., Viveiros, M., Couto, I. & Costa, S. S., 11 Feb 2025, In: Antibiotics. 14, 2, 14 p., 183.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Link opens in a new tab Citations (Scopus)36 Downloads (Pure) -
Evaluation of toxicity and efflux inhibitory activity of candidate drugs for repurposing against Neisseria gonorrhoeae
Santos, B., Henriques, A., Armada, A. & Rodrigues, L., Apr 2024.Research output: Contribution to conference › Poster › peer-review
-
Galleria mellonella: um modelo fidedigno para avaliar a eficácia de fármacos para a terapêutica de infeções provocadas por estafilococos
Andrade, M., Neves, J., Bento, M., Marques, J., Viveiros, M., Rodrigues, L., Armada, A., Silveira, H., Couto, I. & Costa, S. S., 25 Nov 2024. 1 p.Research output: Contribution to conference › Abstract › peer-review
Open AccessFile12 Downloads (Pure) -
Galleria mellonella as a reliable in vivo model to evaluate repurposed drugs for Staphylococcus infection therapeutics
Andrade, M., Neves, J., Bento, M., Marques, J., Viveiros, M., Rodrigues, L., Armada, A., Silveira, H., Couto, I. & Costa, S., 19 Aug 2024.Research output: Contribution to conference › Abstract › peer-review
Open AccessFile14 Downloads (Pure) -
Galleria mellonella research hub: a new in vivo infection model at GHTM/IHMT-NOVA
Andrade, M., Neves, J., Marques, J., Armada, A., Rodrigues, L., Viveiros, M., Silveira, H., Couto, I. & Costa, S. S., 18 Nov 2024, p. 31-31. 1 p.Research output: Contribution to conference › Poster › peer-review
Open AccessFile13 Downloads (Pure)
Prizes
-
H2020-Marie Sklodowska-Curie Individual Fellowship (H2020-MSCA-IF-2017) iCHEMGENODRUGS: Chemogenomics and in silico repurposing as an innovative approach for rapid drug discovery in tuberculosis
Rodrigues, L. I. D. (Recipient), 2018
Prize: Fellowship awarded competitively
Activities
- 12 Oral presentation
-
Galleria mellonella as a reliable in vivo model to evaluate repurposed drugs for Staphylococcus infection therapeutics
Andrade, M. (Speaker), Neves, J. (Speaker), Bento, M. (Speaker), Marques, J. (Speaker), Viveiros, M. (Speaker), Rodrigues, L. I. D. (Speaker), Armada, A. M. B. D. M. M. P. D. (Speaker), Condinho da Silveira, H. M. (Speaker), Couto, I. M. D. S. L. (Speaker) & Santos Costa, S. (Speaker)
19 Aug 2024Activity: Talk or presentation › Oral presentation
-
New candidate drugs for repurposing as efflux inhibitors and antibiofilm agents against antimicrobial-resistant Staphylococcus aureus and Staphylococcus epidermidis
Neves, J. (Speaker), Andrade, M. (Speaker), Bento, M. (Speaker), Viveiros, M. (Speaker), Rodrigues, L. I. D. (Speaker), Couto, I. M. D. S. L. (Speaker) & Santos Costa, S. (Speaker)
19 Aug 2024Activity: Talk or presentation › Oral presentation
-
New candidate drugs for repurposing as efflux inhibitors and antibiofilm agents against antimicrobial-resistant Staphylococcus aureus and Staphylococcus epidermidis
Neves, J. (Speaker), Andrade, M. (Speaker), Bento, M. (Speaker), Couto, I. M. D. S. L. (Speaker), Rodrigues, L. I. D. (Speaker) & Santos Costa, S. (Speaker)
30 Apr 2024Activity: Talk or presentation › Oral presentation
-
O Papel Das Bombas De Efluxo Na Resistência Aos Antimicrobianos Em Isolados Clínicos De Neisseria Gonorrhoeae
Paulino, T. (Speaker), Santos Costa, S. (Speaker) & Rodrigues, L. I. D. (Speaker)
Mar 2024Activity: Talk or presentation › Oral presentation
-
Galleria mellonella: um modelo in vivo fidedigno para avaliar a eficácia de fármacos para a terapêutica de infeções provocadas por estafilococos
Andrade, M. (Speaker), Neves, J. (Speaker), Bento, M. (Speaker), Marques, J. (Speaker), Viveiros, M. (Speaker), Rodrigues, L. I. D. (Speaker), Armada, A. M. B. D. M. M. P. D. (Speaker), Couto, I. M. D. S. L. (Speaker), Condinho da Silveira, H. M. (Speaker) & Santos Costa, S. (Speaker)
25 Nov 2024Activity: Talk or presentation › Oral presentation