• 525 Citations
  • 8 h-Index
20072019
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Personal profile

Research interests

Since my Ph.D. thesis my work has focused on the study of the mechanisms responsible for the emergence of drug resistance in bacteria, namely the contribution of efflux pumps. In particular, I have studied the contribution of efflux pumps in the development of drug resistance in Mycobacterium tuberculosis and other mycobacteria. Moreover, I was involved in the development of methods that allow the detection of efflux activity in bacteria and the in vitro testing of efflux inhibitors. I am also interested in the identification of new drugs, or adjuvants of already existent anti-tuberculosis drugs, that may be used as new therapeutical approaches. From 2011 to 2016, I worked as a post-doctoral researcher at the University of Zaragoza in Spain and was involved in the FP7 project More Medicines for Tuberculosis. Presently, I’m a Marie Curie Fellow (H2020-MSCA-IF-2017: iCHEMGENODRUGS_TB) at GHTM and my main research interest is to explore the novel concepts of drug repurposing and comparative chemogenomics to find new drugs against tuberculosis.

Fingerprint Dive into the research topics where Liliana Isabel Dias Rodrigues is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 6 Similar Profiles
Mycobacterium tuberculosis Medicine & Life Sciences
Tuberculosis Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Ethidium Medicine & Life Sciences
Mycobacterium Medicine & Life Sciences
Bacteria Medicine & Life Sciences
Pumps Chemical Compounds
aminoglycoside 2'-N-acetyltransferase Medicine & Life Sciences

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Research Output at NOVA 2007 2019

  • 525 Citations
  • 8 h-Index
  • 7 Article
  • 1 Review article

O contributo dos serviços de diagnóstico laboratorial para o acesso universal à saúde nos países da Comunidade de Língua Portuguesa

Translated title of the contribution: Laboratory services contribution to supporting public health and health services in Portuguese-speaking countriesML, V., Rodrigues, L., Almeida, F., Fortes, F., Germano de, S., Sandra, M., Silveira, H. & Viveiros, M., 5 Dec 2019, In : Anais do Instituto de Higiene e Medicina Tropical. Vol. 18, p. 42-51 10 p.

Research output: Contribution to journalArticle

Open Access
Health Services
Public Health
Angola
Health Services Accessibility
Portugal

Boldine-derived Alkaloids inhibit the activity of DNA topoisomerase I and growth of Mycobacterium tuberculosis

M. Teresa, G., David, C. D., José Manuel, T-V., María José, F., Rodrigues, L. I. D., Begoña, G., M., A., Aínsa, J. A. & Adela G., D. L. C. A. G., 24 Jul 2018, In : Frontiers in Microbiology. Vol. 9, JUL, p. p. 1659-1667 9 p., 1659.

Research output: Contribution to journalArticle

Open Access
Type I DNA Topoisomerase
Mycobacterium tuberculosis
Alkaloids
Plasmids
Growth
4 Citations (Scopus)

Synergy between circular bacteriocin AS-48 and ethambutol against mycobacterium tuberculosis

Aguilar-Pérez, C., Gracia, B., Rodrigues, L., Vitoria, A., Cebrián, R., Deboosère, N., Song, O. R., Brodin, P., Maqueda, M. & Aínsaa, J. A., 1 Sep 2018, In : Antimicrobial Agents and Chemotherapy. 62, 9, e00359-18.

Research output: Contribution to journalArticle

Ethambutol
Bacteriocins
Mycobacterium tuberculosis
Macrophages
Multidrug-Resistant Tuberculosis
2 Citations (Scopus)

The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase

Giorgia, M., Beatrice Silvia, O., Clara, F., Lesley A., M., Adwait Anand, G., Rodrigues, L. I. D., Clara, A-P., Zemanova, J., Stanislav, H., Martin, F., Thomas R., L., Mohamad, S. M., Nathalie, D., Rosangela, F., Alexandre, V., Eik, H., Riccardo, R. R., Nancy D., C., Courtney A., V., Rajiv, K. & 9 others, Pradeep Ravi, K., Joel S., F., Priscille, B., Aínsa, J. A., Valakunja, N., Anthony, M., Katarína, M., Maria Rosalia, P. & Sean, E., Sep 2018, In : Tuberculosis. Vol. 112, p. 98-109 12 p.

Research output: Contribution to journalArticle

Antimalarials
DNA-Directed RNA Polymerases
Rifampin
Mycobacterium tuberculosis
Drug Repositioning
81 Citations (Scopus)
isoniazid
Mycobacterium tuberculosis complex
tuberculosis
Isoniazid
Mycobacterium tuberculosis