• 736 Citations
  • 14 h-Index
20152020

Research output per year

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Research Output at NOVA

  • 736 Citations
  • 14 h-Index
  • 10 Article
  • 1 Meeting Abstract
  • 1 Review article
  • 1 Other contribution
2020

Hsp27 reduces glycation-induced toxicity and aggregation of alpha-synuclein

Vicente Miranda, H., Chegão, A., Oliveira, M. S., Fernandes Gomes, B., Enguita, F. J. & Outeiro, T. F., 2020, (Accepted/In press) In : Faseb Journal.

Research output: Contribution to journalArticle

2019

Extracellular aggregated alpha synuclein primarily triggers lysosomal dysfunction in neural cells prevented by trehalose

Hoffmann, A. C., Minakaki, G., Menges, S., Salvi, R., Savitskiy, S., Kazman, A., Vicente Miranda, H., Mielenz, D., Klucken, J., Winkler, J. & Xiang, W., 24 Jan 2019, In : Scientific Reports. 9, 1, 544.

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
12 Downloads (Pure)

On the role of astrocytes upon A beta-mediated neurotoxicity

Gomes, J. I., Gomes, J. F., Miranda, H. V., Sebastiao, A. M., Diogenes, M. J. & Vaz, S. H., Jul 2019, In : Glia. 67, p. E222-E222

Research output: Contribution to journalMeeting Abstract

2018

Alpha-Synuclein Glycation and the Action of Anti-Diabetic Agents in Parkinson's Disease

König, A., Vicente Miranda, H. & Outeiro, T. F., 18 Feb 2018, In : Journal of Parkinson's Disease. 8, 1, p. 33-43 11 p.

Research output: Contribution to journalReview article

10 Citations (Scopus)
2017

Correction: The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease

de Oliveira, R. M., Vicente Miranda, H., Francelle, L., Pinho, R., Szegö, É. M., Martinho, R., Munari, F., Lázaro, D. F., Moniot, S., Guerreiro, P., Fonseca-Ornelas, L., Marijanovic, Z., Antas, P., Gerhardt, E., Enguita, F. J., Fauvet, B., Penque, D., Pais, T. F., Tong, Q., Becker, S. & 5 others, Kügler, S., Lashuel, H. A., Steegborn, C., Zweckstetter, M. & Outeiro, T. F., Apr 2017

Research output: Other contribution

Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies

Vicente Miranda, H., Szego, É. M., Oliveira, L. M. A., Breda, C., Darendelioglu, E., De Oliveira, R. M., Ferreira, D. G., Gomes, M. A., Rott, R., Oliveira, M., Munari, F., Enguita, F. J., Simões, T., Rodrigues, E. F., Heinrich, M., Martins, I. C., Zamolo, I., Riess, O., Cordeiro, C., Ponces-Freire, A. & 12 others, Lashuel, H. A., Santos, N. C., Lopes, L. V., Xiang, W., Jovin, T. M., Penque, D., Engelender, S., Zweckstetter, M., Klucken, J., Giorgini, F., Quintas, A. & Outeiro, T. F., 1 May 2017, In : Brain. 140, 5, p. 1399-1419 21 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Posttranslational modifications of blood-derived alpha-synuclein as biochemical markers for Parkinson's disease

Miranda, H. V., Cássio, R., Correia-Guedes, L., Gomes, M. A., Chegão, A., Miranda, E., Soares, T., Coelho, M., Rosa, M. M., Ferreira, J. J. & Outeiro, T. F., 2017, In : Scientific Reports. 7, 1, p. Online 11 p., 13713.

Research output: Contribution to journalArticle

Open Access
File
25 Citations (Scopus)
10 Downloads (Pure)

Synthesis and Biological Evaluation of Novel 2-Aryl Benzimidazoles as Chemotherapeutic Agents

Morais, G. R., Palma, E., Marques, F., Gano, L., Oliveira, M. C., Abrunhosa, A., Miranda, H. V., Outeiro, T. F., Santos, I. & Paulo, A., Jan 2017, In : Journal Of Heterocyclic Chemistry. 54, 1, p. 255-267

Research output: Contribution to journalArticle

1 Citation (Scopus)

The mechanism of sirtuin 2–mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease

de Oliveira, R. M., Vicente Miranda, H., Francelle, L., Pinho, R., Szegö, É. M., Martinho, R., Munari, F., Lázaro, D. F., Moniot, S., Guerreiro, P., Fonseca, L., Marijanovic, Z., Antas, P., Gerhardt, E., Enguita, F. J., Fauvet, B., Penque, D., Pais, T. F., Tong, Q., Becker, S. & 5 others, Kügler, S., Lashuel, H. A., Steegborn, C., Zweckstetter, M. & Outeiro, T. F., Mar 2017, In : PLoS Biology. 15, 3, p. Online 27 p.

Research output: Contribution to journalArticle

Open Access
File
45 Citations (Scopus)
9 Downloads (Pure)

α-synuclein interacts with PrP C to induce cognitive impairment through mGluR5 and NMDAR2B

Ferreira, D. G., Temido-Ferreira, M., Miranda, H. V., Batalha, V. L., Coelho, J. E., Szegö, É. M., Marques-Morgado, I., Vaz, S. H., Rhee, J. S., Schmitz, M., Zerr, I., Lopes, L. V. & Outeiro, T. F., 1 Jan 2017, In : Nature Neuroscience. 20, 11, p. 1569-1579 11 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)
2016

Glycation in Parkinson's disease and Alzheimer's disease

Vicente Miranda, H., El-Agnaf, O. M. A. & Outeiro, T. F., Jun 2016, In : Movement disorders : official journal of the Movement Disorder Society. 31, 6, p. 782-90 9 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Glycation potentiates neurodegeneration in models of Huntington's disease

Miranda, H. V., Gomes, M. A., Branco-Santos, J., Breda, C., Lazaro, D. F., Lopes, L. V., Herrera, F., Giorgini, F. & Outeiro, T. F., 18 Nov 2016, In : Scientific Reports. 6

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
6 Downloads (Pure)
2015

Isostructural Re(I)/Tc-99m(I) tricarbonyl complexes for cancer theranostics

Nunes, P., Morais, G. R., Palma, E., Silva, F., Oliveira, M. C., Ferreira, V. F. C., Mendes, F., Gano, L., Vicente Miranda, H., Outeiro, T. F., Santos, I. & Paulo, A., 2015, In : Organic & Biomolecular Chemistry. 13, 18, p. 5182-5194 13 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)