If you made any changes in Pure these will be visible here soon.

Personal profile

Research interests

http://orcid.org/0000-0001-8065-9259

Education/Academic qualification

Biochemistry, Doctorate, Universidade de Lisboa

1 Jan 200620 Jan 2010

Biochemistry, Bachelor, Universidade de Lisboa

11 Sep 200012 Jul 2005

Fingerprint Dive into the research topics where Hugo Vicente Miranda is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 11 Similar Profiles
Synucleins Medicine & Life Sciences
alpha-Synuclein Medicine & Life Sciences
Parkinson Disease Medicine & Life Sciences
Pyruvaldehyde Medicine & Life Sciences
Post Translational Protein Processing Medicine & Life Sciences
Sirtuin 2 Medicine & Life Sciences
Proteins Medicine & Life Sciences
Neurodegenerative Diseases Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2015 2019

  • 166 Citations
  • 7 h-Index
  • 9 Article
  • 1 Review article
  • 1 Other contribution
3 Citations (Scopus)
10 Downloads (Pure)

Extracellular aggregated alpha synuclein primarily triggers lysosomal dysfunction in neural cells prevented by trehalose

Hoffmann, A. C., Minakaki, G., Menges, S., Salvi, R., Savitskiy, S., Kazman, A., Vicente Miranda, H., Mielenz, D., Klucken, J., Winkler, J. & Xiang, W., 24 Jan 2019, In : Scientific Reports. 9, 1, 544.

Research output: Contribution to journalArticle

Open Access
File
alpha-Synuclein
Trehalose
Lysosomes
Endosomes
Autophagy

Alpha-Synuclein Glycation and the Action of Anti-Diabetic Agents in Parkinson's Disease

König, A., Vicente Miranda, H. & Outeiro, T. F., 18 Feb 2018, In : Journal of Parkinson's Disease. 8, 1, p. 33-43 11 p.

Research output: Contribution to journalReview article

alpha-Synuclein
Parkinson Disease
Advanced Glycosylation End Products
Proteins
Diabetes Complications

Correction: The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease

de Oliveira, R. M., Vicente Miranda, H., Francelle, L., Pinho, R., Szegö, É. M., Martinho, R., Munari, F., Lázaro, D. F., Moniot, S., Guerreiro, P., Fonseca-Ornelas, L., Marijanovic, Z., Antas, P., Gerhardt, E., Enguita, F. J., Fauvet, B., Penque, D., Pais, T. F., Tong, Q., Becker, S. & 5 othersKügler, S., Lashuel, H. A., Steegborn, C., Zweckstetter, M. & Outeiro, T. F., Apr 2017

Research output: Other contribution

Sirtuin 2
alpha-Synuclein
Parkinson Disease
32 Citations (Scopus)

Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies

Vicente Miranda, H., Szego, É. M., Oliveira, L. M. A., Breda, C., Darendelioglu, E., De Oliveira, R. M., Ferreira, D. G., Gomes, M. A., Rott, R., Oliveira, M., Munari, F., Enguita, F. J., Simões, T., Rodrigues, E. F., Heinrich, M., Martins, I. C., Zamolo, I., Riess, O., Cordeiro, C., Ponces-Freire, A. & 12 othersLashuel, H. A., Santos, N. C., Lopes, L. V., Xiang, W., Jovin, T. M., Penque, D., Engelender, S., Zweckstetter, M., Klucken, J., Giorgini, F., Quintas, A. & Outeiro, T. F., 1 May 2017, In : Brain. 140, 5, p. 1399-1419 21 p.

Research output: Contribution to journalArticle

Synucleins
Poisons
Drosophila
Post Translational Protein Processing
Synaptic Transmission
13 Citations (Scopus)
4 Downloads (Pure)

Posttranslational modifications of blood-derived alpha-synuclein as biochemical markers for Parkinson's disease

Miranda, H. V., Cássio, R., Correia-Guedes, L., Gomes, M. A., Chegão, A., Miranda, E., Soares, T., Coelho, M., Rosa, M. M., Ferreira, J. J. & Outeiro, T. F., 2017, In : Scientific Reports. 7, 1, p. Online 11 p., 13713.

Research output: Contribution to journalArticle

Open Access
File
alpha-Synuclein
Post Translational Protein Processing
Parkinson Disease
Biomarkers
Disease Progression

Prizes

Best Poster Award

Hugo Vicente Miranda (Recipient), 2014

Prize: National/international honour