Research output per year
Research output per year
Personal profile
Research interests
Overall, our lab is interested in determining how immune receptor signaling is able to convey distinct immune responses that protect us against disparate aggressions (fungus, virus, bacteria, cancer, etc.).
Our current research is comprised of three interconnected axis:
1- To establish how signaling architecture regulates immune responses;
2- To determine how alterations in signaling lead to auto-immunity;
3- To decipher how pathogens (HIV-1) exploit the immune signaling to their own advantage.
Education/Academic qualification
Biomedicine, Doctorate, The Rockefeller University
4 Nov 2004 → 27 Nov 2006
Award Date: 27 Nov 2006
Pharmaceutical Sciences, Universidade de Coimbra
5 Nov 1995 → 29 Jun 2001
Award Date: 29 Jun 2001
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Effects of spike protein and toxin-like peptides found in COVID-19 patients on human 3D neuronal/glial model undergoing differentiation: Possible implications for SARS-CoV-2 impact on brain development
Francesca, P., Mauro, P., Clerbaux, L. A., Leoni, G., Ponti, J., Bogni, A., Brogna, C., Cristoni, S., Sanges, R., Mendoza-de Gyves, E., Fabbri, M., Querci, M., Soares, H., Munoz, A., Whelan, M. & Van de Eede, G., Aug 2022, In: Reproductive Toxicology. 111, p. 34-48 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)2 Downloads (Pure) -
Factors Modulating COVID-19: A Mechanistic Understanding Based on the Adverse Outcome Pathway Framework
Clerbaux, L. A., Albertini, M. C., Amigó, N., Beronius, A., Bezemer, G. F. G., Coecke, S., Daskalopoulos, E. P., del Giudice, G., Greco, D., Grenga, L., Mantovani, A., Muñoz, A., Omeragic, E., Parissis, N., Petrillo, M., Saarimäki, L. A., Soares, H., Sullivan, K. & Landesmann, B., Aug 2022, In: Journal of Clinical Medicine. 11, 15, 4464.Research output: Contribution to journal › Review article › peer-review
Open AccessFile6 Citations (Scopus)33 Downloads (Pure) -
Gut as an Alternative Entry Route for SARS-CoV-2: Current Evidence and Uncertainties of Productive Enteric Infection in COVID-19
Clerbaux, L. A., Mayasich, S. A., Muñoz, A., Soares, H., Petrillo, M., Albertini, M. C., Lanthier, N., Grenga, L. & Amorim, M. J., Oct 2022, In: Journal of Clinical Medicine. 11, 19, 5691.Research output: Contribution to journal › Review article › peer-review
Open AccessFile1 Citation (Scopus)4 Downloads (Pure) -
COVID-19 mRNA vaccine and antibody response in lactating women: a prospective cohort study
Charepe, N., Gonçalves, J., Juliano, A. M., Lopes, D. G., Canhão, H., Soares, H. & Serrano, E. F., Dec 2021, In: BMC pregnancy and childbirth. 21, 1, 632.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (Scopus)44 Downloads (Pure) -
Development of triazoles and triazolium salts based on azt and their anti-viral activity against hiv-1
de Alencar, D. M., Gonçalves, J., Vieira, A., Cerqueira, S. A., Sebastião, C., Leitão, M. I. P. S., Francescato, G., Antenori, P., Soares, H. & Petronilho, A., 1 Nov 2021, In: Molecules. 26, 21, 6720.Research output: Contribution to journal › Article › peer-review
Open Access
Prizes
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Bridging Innate and Adaptive Immunity through JAK signalling
Soares, Helena (Recipient), 30 Jun 2017
Prize: Fellowship awarded competitively
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Development of Novel AZT Derivatives Based on Triazoles
Soares, Helena (Recipient), 30 Sep 2017
Prize: Fellowship awarded competitively
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HIV-1 Replication in Follicular Sanctiaries
Soares, Helena (Recipient), 6 Apr 2017
Prize: Fellowship awarded competitively
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Rewired T Cells: New therapeutic opportunities for Rheumatoid Arthritis
Soares, Helena (Recipient), 1 Apr 2016
Prize: Fellowship awarded competitively
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Rewired T Cells: New therapeutic opportunities for Rheumatoid Arthritis
Soares, Helena (Recipient), 1 Apr 2016
Prize: Fellowship awarded competitively