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António José Cabrita Lucas Laires

  • 1481 Citations
  • 22 h-Index
1982 …2012

Research output per year

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Article
2012

DNA damage response in imatinib resistant chronic myeloid leukemia K562 cells.

Dinis, J., Silva, V., Gromicho, M., Martins, C., Laires, A., Tavares, P., Rendeiro, P., Torres, F., Rueff, J. & Rodrigues, AS., 2012, In : Leukemia & Lymphoma. 53, 10, p. 2004-14 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Estragole: A weak direct-acting food-borne genotoxin and potential carcinogen

Martins, C., Cação, R., Cole, K. J., Phillips, D. H., Laires, A., Rueff, J. & Rodrigues, A. S., 2012, In : Mutation Research-Genetic Toxicology And Environmental Mutagenesis. 747, 1, p. 86-92 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Genomics and Cancer Drug Resistance

Rodrigues, A. S., Dinis, J., Gromicho, M., Martins, C., Laires, A. & Rueff, J., 1 Jan 2012, In : Current Pharmaceutical Biotechnology. 13, 5, p. 651-673

Research output: Contribution to journalArticle

32 Citations (Scopus)
2011
43 Citations (Scopus)
2010
3 Citations (Scopus)
2006

Genotoxicity and endoreduplication inducing activity of the food flavouring eugenol

Maralhas, A., Monteiro, A., Martins, C., Kranendonk, M., Laires, A., Rueff, J. & Rodrigues, A. S., 2006, In : Mutagenesis. 21, 3, p. 199-204 5 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Lipoperoxidation products and thiol antioxidants in chromium exposed workers

Goulart, M., Batoréu, M. C., Rodrigues, A. S., Laires, A. J. C. L. & Rueff, J., Sep 2005, In : Mutagenesis. 20, 5, p. 311-315 5 p.

Research output: Contribution to journalArticle

Open Access
72 Citations (Scopus)
20 Citations (Scopus)
2003
Open Access
83 Citations (Scopus)

Elevated levels of DNA-protein crosslinks and micronuclei in peripheral lymphocytes of tannery workers exposed to trivalent chromium

Medeiros, MG., Rodrigues, AS., Batoreu, MC., Laires, A., Rueff, J. & Zhitkovich, A., Jan 2003, In : Mutagenesis. 18, 1, p. 19-24

Research output: Contribution to journalArticle

74 Citations (Scopus)
2002

Possible transient adaptive response to mitomycin C in peripheral lymphocytes from thyroid cancer patients after iodine-131 therapy

Gil, O. M., Oliveira, N. G., Rodrigues, A. S., Laires, A., Ferreira, T. C., Limbert, E. & Rueff, J., 1 Jan 2002, In : International Journal of Cancer. 102, 6, p. 556-561

Research output: Contribution to journalArticle

10 Citations (Scopus)
2000
84 Citations (Scopus)

Cytogenetic alterations and oxidative stress in thyroid cancer patients after iodine-131 therapy

Gil, O. M., Oliveira, N. G., Rodrigues, A. S., Laires, A., Ferreira, T. C., Limbert, E., Leonard, A., Gerber, G. & Rueff, J., 2000, In : Mutagenesis. 15, 1, p. 69-75

Research output: Contribution to journalArticle

43 Citations (Scopus)
88 Citations (Scopus)

No evidence of increased chromosomal aberrations and micronuclei in lymphocytes from nonfamilial thyroid cancer patients prior to radiotherapy

Gil, O. M., Oliveira, N. G., Rodrigues, A. S., Laires, A., Ferreira, T. C., Limbert, E. & Rueff, J., Nov 2000, In : Cancer Genetics And Cytogenetics. 123, 1, p. 55-60

Research output: Contribution to journalArticle

14 Citations (Scopus)
1999
29 Citations (Scopus)

Escherichia coli MTC, a NADPH cytochrome P450 reductase competent mutagenicity tester strain for the expression of human cytochrome P450: Comparison of three types of expression systems

Kranendonk, M., Fisher, C. W., Roda, R., Carreira, F., Theisen, P., Laires, A., Rueff, J., Vermeulen, N. P. E. & Estabrook, R. W., 19 Feb 1999, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 439, 2, p. 287-300 14 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
1998

Expression of human cytochrome P450 1A2 in Escherichia coli: A system for biotransformation and genotoxicity studies of chemical carcinogens

Kranendonk, M., Mesquita, P., Laires, A., Vermeulen, N. P. E. & Rueff, J., May 1998, In : Mutagenesis. 13, 3, p. 263-269 7 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)
1997
25 Citations (Scopus)
2 Citations (Scopus)
46 Citations (Scopus)
38 Citations (Scopus)
1996

Mechanisms of myricetin mutagenicity in V79 cells: Involvement of radicalar species

Duarte Silva, I., Gaspar, J., Rodrigues, A., Gomes da Costa, G., Laires, A. & Rueff, J., 1996, In : Teratogenesis Carcinogenesis And Mutagenesis. 16, 5, p. 253-268 16 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
6 Citations (Scopus)

Mutagenicity of kaempferol in V79 cells: The role of cytochromes P450

Duarte Silva, I., Rodrigues, A., Gaspar, J., Maia, R., Laires, A. & Rueff, J., 1996, In : Teratogenesis Carcinogenesis And Mutagenesis. 16, 4, p. 229-241 13 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

MX100, a new Escherichia coli tester strain for use in genotoxicity studies

Kranendonk, M., Pintado, F., Mesquita, P., Laires, A., Vermeulen, N. P. E. & Rueff, J., Jul 1996, In : Mutagenesis. 11, 4, p. 327-333 7 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
1995
74 Citations (Scopus)

Structural requirements for mutagenicity of flavonoids upon nitrosation. A structure-activity study

Rueff, J., Gaspar, J. & Laires, A., 1 Jul 1995, In : Mutagenesis. 10, 4, p. 325-328 4 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
1994
5 Citations (Scopus)

Genotoxicity assessment of aromatic-amines and amides in genetically-engineered v79 cells

Silva, ID., Caria, M. H., Laires, A., Chaveca, T., Glatt, HR., Rueff, J. & Rodrigues, AS., Dec 1994, In : Mutation research-Genetic toxicology. 341, 2, p. 93-100 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
12 Citations (Scopus)

On the mechanisms of genotoxicity and metabolism of quercetin

Gaspar, J., Rodrigues, A., Laires, A., Silva, F., Costa, S., Monteiro, M. J., Monteiro, C. & Rueff, J., Sep 1994, In : Mutagenesis. 9, 5, p. 445-449 5 p.

Research output: Contribution to journalArticle

66 Citations (Scopus)
1993
17 Citations (Scopus)

Quercetin and the mutagenicity of wines

Gaspar, J., Laires, A., Monteiro, M., Laureano, O. & Ramos, E., 1 Jan 1993, In : Mutagenesis. 8, 1, p. 51-55 5 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
1992
11 Citations (Scopus)
46 Citations (Scopus)
1990

Mutagenic activity in the wine-making process: Correlations with rutin and quercetin levels

Rueff, J., Laires, A., Gaspar, J. & Rodrigues, A., Jul 1990, In : Mutagenesis. 5, 4, p. 393-396 4 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
1989
17 Citations (Scopus)
1986

Genetic toxicology of flavonoids: The role of metabolic conditions in the induction of reverse mutation, SOS functions and sisterchromatid exchanges

Rueff, J., Laires, A., Borba, H., Chaveca, T., Gomes, M. I. & Halpern, M., May 1986, In : Mutagenesis. 1, 3, p. 179-183 5 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)
1982

Mutagenicity in urine of workers in naval industry.

Rueff, J., Laires, A., Gomes, M. I., Borba, H., Magalhães, J. & Halpern, M., 1 Dec 1982, In : Progress in clinical and biological research. 109, p. 443-452 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Urinary mutagenicity in occupational exposure to mineral oils and iron oxide particles

Laires, A., Borba, H., Rueff, J., Gomes, M. I. & Halpern, M., 1982, In : Carcinogenesis. 3, 9, p. 1077-1079 3 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)