No photo of António José Cabrita Lucas Laires

António José Cabrita Lucas Laires

  • 1495 Citations
  • 22 h-Index
1982 …2012

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output at NOVA

Review article

Heterologous expression of xenobiotic mammalian-metabolizing enzymes in mutagenicity tester bacteria: An update and practical considerations

Kranendonk, M., Laires, A., Rueff, J., Estabrook, R. W. & Vermeulen, N. P. E., 2000, In : Critical Reviews In Toxicology. 30, 3, p. 287-306 20 p.

Research output: Contribution to journalReview article

16 Citations (Scopus)
Other contribution

EVALUATION OF DSBS REPAIR IN IMATINIB RESISTANT CELL LINES

Dinis, R., Gromicho, L., Laires, A., Martins, C., Rueff, J. & Rodrigues, AS., 1 Jan 2009, Berlin, GERMANY

Research output: Other contribution

Meeting Abstract

BIOMIMETIC ACTIVATION OF PREMUTAGENS WITH FETPP AND VARIOUS OXYGEN DONORS

Rodrigues, AS., Rueff, J., Laires, A. & Gaspar, J., Apr 1992, In : Mutation research. 271, 2, p. 158-158 1 p.

Research output: Contribution to journalMeeting Abstract

Chemical-stability of quercetin - influence on its genotoxicity

Laires, A., Rueff, J., Rodrigues, AS., Gaspar, J., Chaveca, T. & David, V., Oct 1989, In : Mutation research. 216, 5, p. 300-300 1 p.

Research output: Contribution to journalMeeting Abstract

MUTAGENIC ACTIVITY IN ALCOHOLIC FERMENTATION

Laires, A., Rueff, J., Gaspar, J. & Rodrigues, AS., Jun 1988, In : Mutation research. 203, 3, p. 238-239 2 p.

Research output: Contribution to journalMeeting Abstract

MUTAGENICITY IN URINE OF WORKERS IN THE NAVAL INDUSTRY

RUEFF, J., LAIRES, A., GOMES, M., BORBA, H. & HALPERN, M., 1983, In : Mutation research. 113, 3-4, p. 301-302

Research output: Contribution to journalMeeting Abstract

Literature review

Development and validation of alternative metabolic systems for mutagenicity testing in short-term assays

Rueff, J., Chiapella, C., Chipman, JK., Darroudi, F., Silva, ID., DuvergervanBogaert, M., Fonti, E., Glatt, HR., Isern, P., Laires, A., Leonard, A., Llagostera, M., Mossesso, P., Natarajan, AT., Palitti, F., Rodrigues, AS., Schinoppi, A., Turchi, G. & WerleSchneider, G., 12 Jun 1996, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 353, 1-2, p. 151-176 26 p.

Research output: Contribution to journalLiterature review

61 Citations (Scopus)
Conference contribution

Activation of promutagens by rat cyp p450 expressing v79 cells

Rodrigues, AS., Silva, ID., Monteiro, M. J., Caria, H., Laires, A., Chaveca, T. & Rueff, J., 1994, CYTOCHROME P450. Lechner, MC. (ed.). JOHN LIBBEY EUROTEXT LTD, p. 205-208 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

DNA DAMAGE AND OXYGEN SPECIES

Rueff, J., Laires, A., Brás, A., Borba, H., Chaveca, T., Gaspar, J., Rordrigues, A., Cristovão, L. & Monteiro, M., 1989, DNA REPAIR MECHANISMS AND THEIR BIOLOGICAL IMPLICATIONS IN MAMMALIAN CELLS. LAMBERT, MW. & LAVAL, J. (eds.). PLENUM PRESS DIV PLENUM PUBLISHING CORP, p. 171-181 11 p. (NATO ADVANCED SCIENCE INSTITUTES SERIES, SERIES A, LIFE SCIENCES; vol. 182).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Chapter

Biomarkers of Chromium Exposure and Cytogenetic damage in Leather Tanning and Welding Industry Workers

Medeiros, M. G., Rodrigues, A., Batoreu, C., Laires, A., Rueff, J. & Zhitkovich, A., 1 Jan 2003, Human Monitoring for Genetic Effects. N. S. S. (ed.). IOS Press

Research output: Chapter in Book/Report/Conference proceedingChapter

Article
11 Citations (Scopus)
Open Access
84 Citations (Scopus)
25 Citations (Scopus)
84 Citations (Scopus)

Cytogenetic alterations and oxidative stress in thyroid cancer patients after iodine-131 therapy

Gil, O. M., Oliveira, N. G., Rodrigues, A. S., Laires, A., Ferreira, T. C., Limbert, E., Leonard, A., Gerber, G. & Rueff, J., 2000, In : Mutagenesis. 15, 1, p. 69-75

Research output: Contribution to journalArticle

43 Citations (Scopus)
43 Citations (Scopus)

DNA damage response in imatinib resistant chronic myeloid leukemia K562 cells.

Dinis, J., Silva, V., Gromicho, M., Martins, C., Laires, A., Tavares, P., Rendeiro, P., Torres, F., Rueff, J. & Rodrigues, AS., 2012, In : Leukemia & Lymphoma. 53, 10, p. 2004-14 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Elevated levels of DNA-protein crosslinks and micronuclei in peripheral lymphocytes of tannery workers exposed to trivalent chromium

Medeiros, MG., Rodrigues, AS., Batoreu, MC., Laires, A., Rueff, J. & Zhitkovich, A., Jan 2003, In : Mutagenesis. 18, 1, p. 19-24

Research output: Contribution to journalArticle

76 Citations (Scopus)
29 Citations (Scopus)

Escherichia coli MTC, a NADPH cytochrome P450 reductase competent mutagenicity tester strain for the expression of human cytochrome P450: Comparison of three types of expression systems

Kranendonk, M., Fisher, C. W., Roda, R., Carreira, F., Theisen, P., Laires, A., Rueff, J., Vermeulen, N. P. E. & Estabrook, R. W., 19 Feb 1999, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 439, 2, p. 287-300 14 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Estragole: A weak direct-acting food-borne genotoxin and potential carcinogen

Martins, C., Cação, R., Cole, K. J., Phillips, D. H., Laires, A., Rueff, J. & Rodrigues, A. S., 2012, In : Mutation Research-Genetic Toxicology And Environmental Mutagenesis. 747, 1, p. 86-92 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Expression of human cytochrome P450 1A2 in Escherichia coli: A system for biotransformation and genotoxicity studies of chemical carcinogens

Kranendonk, M., Mesquita, P., Laires, A., Vermeulen, N. P. E. & Rueff, J., May 1998, In : Mutagenesis. 13, 3, p. 263-269 7 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)
2 Citations (Scopus)

Genetic toxicology of flavonoids: The role of metabolic conditions in the induction of reverse mutation, SOS functions and sisterchromatid exchanges

Rueff, J., Laires, A., Borba, H., Chaveca, T., Gomes, M. I. & Halpern, M., May 1986, In : Mutagenesis. 1, 3, p. 179-183 5 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Genomics and Cancer Drug Resistance

Rodrigues, A. S., Dinis, J., Gromicho, M., Martins, C., Laires, A. & Rueff, J., 1 Jan 2012, In : Current Pharmaceutical Biotechnology. 13, 5, p. 651-673

Research output: Contribution to journalArticle

32 Citations (Scopus)
5 Citations (Scopus)

Genotoxicity and endoreduplication inducing activity of the food flavouring eugenol

Maralhas, A., Monteiro, A., Martins, C., Kranendonk, M., Laires, A., Rueff, J. & Rodrigues, A. S., 2006, In : Mutagenesis. 21, 3, p. 199-204 5 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Genotoxicity assessment of aromatic-amines and amides in genetically-engineered v79 cells

Silva, ID., Caria, M. H., Laires, A., Chaveca, T., Glatt, HR., Rueff, J. & Rodrigues, AS., Dec 1994, In : Mutation research-Genetic toxicology. 341, 2, p. 93-100 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
17 Citations (Scopus)
74 Citations (Scopus)
88 Citations (Scopus)
47 Citations (Scopus)
12 Citations (Scopus)

Lipoperoxidation products and thiol antioxidants in chromium exposed workers

Goulart, M., Batoréu, M. C., Rodrigues, A. S., Laires, A. J. C. L. & Rueff, J., Sep 2005, In : Mutagenesis. 20, 5, p. 311-315 5 p.

Research output: Contribution to journalArticle

Open Access
75 Citations (Scopus)

Mechanisms of myricetin mutagenicity in V79 cells: Involvement of radicalar species

Duarte Silva, I., Gaspar, J., Rodrigues, A., Gomes da Costa, G., Laires, A. & Rueff, J., 1996, In : Teratogenesis Carcinogenesis And Mutagenesis. 16, 5, p. 253-268 16 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
38 Citations (Scopus)

Mutagenic activity in the wine-making process: Correlations with rutin and quercetin levels

Rueff, J., Laires, A., Gaspar, J. & Rodrigues, A., Jul 1990, In : Mutagenesis. 5, 4, p. 393-396 4 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
6 Citations (Scopus)

Mutagenicity in urine of workers in naval industry.

Rueff, J., Laires, A., Gomes, M. I., Borba, H., Magalhães, J. & Halpern, M., 1 Dec 1982, In : Progress in clinical and biological research. 109, p. 443-452 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Mutagenicity of kaempferol in V79 cells: The role of cytochromes P450

Duarte Silva, I., Rodrigues, A., Gaspar, J., Maia, R., Laires, A. & Rueff, J., 1996, In : Teratogenesis Carcinogenesis And Mutagenesis. 16, 4, p. 229-241 13 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
17 Citations (Scopus)

MX100, a new Escherichia coli tester strain for use in genotoxicity studies

Kranendonk, M., Pintado, F., Mesquita, P., Laires, A., Vermeulen, N. P. E. & Rueff, J., Jul 1996, In : Mutagenesis. 11, 4, p. 327-333 7 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
3 Citations (Scopus)

No evidence of increased chromosomal aberrations and micronuclei in lymphocytes from nonfamilial thyroid cancer patients prior to radiotherapy

Gil, O. M., Oliveira, N. G., Rodrigues, A. S., Laires, A., Ferreira, T. C., Limbert, E. & Rueff, J., Nov 2000, In : Cancer Genetics And Cytogenetics. 123, 1, p. 55-60

Research output: Contribution to journalArticle

14 Citations (Scopus)

On the mechanisms of genotoxicity and metabolism of quercetin

Gaspar, J., Rodrigues, A., Laires, A., Silva, F., Costa, S., Monteiro, M. J., Monteiro, C. & Rueff, J., Sep 1994, In : Mutagenesis. 9, 5, p. 445-449 5 p.

Research output: Contribution to journalArticle

66 Citations (Scopus)
46 Citations (Scopus)

Possible transient adaptive response to mitomycin C in peripheral lymphocytes from thyroid cancer patients after iodine-131 therapy

Gil, O. M., Oliveira, N. G., Rodrigues, A. S., Laires, A., Ferreira, T. C., Limbert, E. & Rueff, J., 1 Jan 2002, In : International Journal of Cancer. 102, 6, p. 556-561

Research output: Contribution to journalArticle

10 Citations (Scopus)