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Impact of the (epi)genome-transcriptome cross-talk in cellular homeostasis and human health

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Ana Rita Grosso gathered a Biology degree (FCUL, 2002), followed by a MSc in Bioinformatics (FCUL-IGC, 2006). Her multi-omics expertise in biomedical research was accomplished by gathering a PhD in Biomedical Sciences (iMM/FMUL, 2010), where she unveiled the existence of splicing-factors expression signatures responsible by the tissue-specific regulation of alternative splicing. During her PostDoc (iMM) she disclosed new mechanisms underlying splicing and transcription dynamics.

In 2018, Ana Rita Grosso moved to NOVA School of Science and Technology (FCT-NOVA) and Applied Molecular Biosciences Unit (UCIBIO) to foster her scientific independence and consolidate her research group: Computational Multi-Omics. Her main mission is to decipher pathological conditions using multi-omics approaches, identifying molecular events to be further used as biomarkers and therapeutic targets. Highlighting, she has been unveiling (epi)genome/transcriptome alterations that affects tumor evolution and metastasis development. To date, Ana Rita Grosso published 45 papers and 2 chapter books (enclosing 1872 citations). Also, she won in highly competitive schemes: 4 Salary Grants (PhD and PostDoc Fellowships, 2 Research Contracts); 10 Projects Grants (4 as PI/Co-PI and 6 as Team Member), 1 EMBO Workshop, as well as 3 Pfizer Awards for Basic Research. Finally, she has been fostering advance training in the computational biology field by supervising 4 PostDoc researchers, 3 PhD students, 3 MSc fellows, 10 MSc students, 7 BSc students and several short-term trainees. Additionally, she has been teaching MSc and BSc courses focused on Genomics and Computational Biology fields in FCT-NOVA.

Education/Academic qualification

Ciências Biomedicas , Doctorate, New insights into alternative splicing using microarray technology , Universidade de Lisboa

Award Date: 28 Feb 2010

Bioinformatica, Master, Statistical Methodologies for the Analysis of DNA Microarray Data, Universidade de Lisboa

Award Date: 5 Jun 2006

Biologia, Bachelor, Estudo Filogenético de Populações Europeias de Columba palumbus (Pombo-Torcaz), Recorrendo à Análise de DNA Mitocondrial, Universidade de Lisboa

Award Date: 22 Sept 2002

External positions

Researcher, Instituto de Medicina Molecular João Lobo Antunes - iMM

1 Jan 201531 Dec 2017

Post-Doctoral Investigator, Instituto de Medicina Molecular João Lobo Antunes - iMM

1 Mar 201031 Dec 2014


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