• 957 Citations
  • 15 h-Index
19972020

Research output per year

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Personal profile

Personal information

Ana Paula Arez is Principal Investigator (with Habilitation) at the Medical Parasitology Unit of Institute of Hygiene and Tropical Medicine (IHMT) and at Global Health and Tropical Medicine Center (GHTM) of Universidade NOVA de Lisboa (UNL). She holds a PhD in Biology (2000) and a BSc in Biology (1992) by the Faculty of Sciences, University of Lisbon.

At IHMT, she is vice-President of the Institute Council, member of the Scientific Council, Coordinator of the GHTM’s Cross Cutting Issue Diagnostics and General Coordinator of the GHTM biobank - Biotropical Resources.

She teaches at Biomedical Sciences, Parasitology and Global Health PhD and MSc courses and have supervised three post-docs, and/or co-supervised seven PhD and 12 MSc students.

Academic Editor of PLoS ONE since 2011 and Regular peer-reviewer in several scientific journals (ID publons.com/a/806560). Expert-Reviewer of scientific projects in national and international funding agencies: The Executive Agency for Higher Education, Research, Development and Innovation Funding, Romania; Research Foundation Flanders (FWO), Belgium; Foundation of Science and Technology, Portugal and Wellcome Trust (training fellowships), United Kingdom.

Research interests

Her research focus three main lines of research: 1) Molecular epidemiology of malaria and characterization and transmission dynamics of parasite populations, 2) Human host and parasite interactions, namely human factors of susceptibility and resistance against malaria and 3) Development of new diagnostic methods for early and multifunctional detection and characterization of malaria infection. Due to a strong background on Ecology acquired during the BSc degree, her first interest has been parasite epidemiology, especially malaria, transmission dynamics and interactions and ecological relationships between different parasites co-infecting the same host. Within this scope, she conducted several research projects in malaria endemic areas, namely Guinea-Bissau, Cape Verde, Mozambique, and Equatorial Guinea. The interesting observations made in Cape Verde led to a new line of research investigating which human host factors and mechanisms, especially related to the Red Blood Cell metabolic pathways, may affect the susceptibility or resistance to malaria infection. Additionally, in this search for new effective tools to fight malaria and aware that prompt and accurate diagnosis is essential to prevent a mild malaria case from developing into severe disease and death, she has been involved in studies to develop new simple, rapid and sensitive molecular diagnostic tests to characterise malaria infected isolates.

Education/Academic qualification

Biology, Doctorate, Faculdade de Ciências, Universidade de Lisboa

Keywords

  • Q Science (General)
  • Malaria
  • Diversity
  • Epidemiology
  • Transmission
  • Molecular markers
  • Plasmodium sp.
  • Parasite-host interactions
  • Human susceptibility/resistance
  • Diagnostics

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Research Output at NOVA

Co-Inheritance of alpha-thalassemia and sickle cell disease in a cohort of Angolan pediatric patients

Santos, B., Delgadinho, M., Ferreira, J., Germano, I., Miranda, A., Arez, A. P., Faustino, P. & Brito, M., 6 Jul 2020, In : Molecular Biology Reports.

Research output: Contribution to journalArticle

  • The role of alpha-thalassemia in sickle cell disease phenotype in Angolan pediatric patients

    Brito, M., Santos, B., Delgadinho, M., Ferreira, J., Jeremias, I., Panzo, M., Catumbela, L., Salvador, G., Valentim, I., Zagi, F., Silva, F., Germano, I., Miranda, A., Arez, A. P. & Faustino, P., 2020, p. 40. 1 p.

    Research output: Contribution to conferenceAbstract

    Genetic dissociation of three antigenic genes in Plasmodium ovale curtisi and Plasmodium ovale wallikeri

    Naowarat Tanomsing, S., François H., N., Colin J., S., Arez, AP., Snounou, G., White, N. J., Nicholas P.J., D., Arjen M., D. & Imwong, M., 6 Jun 2019, In : PlosOne. Vol. 14, n.º 6, p. e0217795-e0217806 14 p., e0217795.

    Research output: Contribution to journalArticle

    Open Access
  • Malaria determining risk factors at the household level in two rural villages of mainland Equatorial Guinea

    Guerra, M., de Sousa, B., Ndong-Mabale, N., Berzosa, P. & Arez, A. P., 18 May 2018, In : Malaria Journal. 17, 1, p. 203

    Research output: Contribution to journalArticle

    Open Access
    File
  • 33 Downloads (Pure)

    Plasmodium falciparum genetic diversity in continental Equatorial Guinea before and after introduction of artemisinin based combination therapy

    Guerra, M., Neres, R., Salgueiro, P., Mendes, C., Ndong-Mabale, N., Berzosa, P., de Sousa, B. & Arez, A. P., 1 Jan 2017, In : Antimicrobial Agents and Chemotherapy. 61, 1, e02556.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 10 Citations (Scopus)
    22 Downloads (Pure)