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Ana Madalena Ludovice

PhD

Former affiliation
 https://orcid.org/0000-0001-7100-7574
  • 396 Citations
  • 10 h-Index
19972019

Research output per year

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Personal profile

Research interests

Microbiology and Molecular Genetics of Gram-positive bacteria. Research interests have been addressed to the understanding the regulatory networks on cell wall physiology in the methicillin-resistant Staphylococcus aureus (MRSA), that possess one of the most effective resistance mechanisms to all beta-lactam antibiotics, namely in: cell wall turnover/recycling; cell wall synthesis and division and the global cell response to the environmental stress.

Education/Academic qualification

Ph.D in Genetics, Doctorate

Award Date: 5 Feb 1993

Master in Biotecnology, Master

Award Date: 3 Mar 1986

Degree in Biology

Award Date: 2 Sep 1980

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Research Output at NOVA

  • 396 Citations
  • 10 h-Index
  • 11 Article

Role of MurT C-Terminal Domain in the Amidation of Staphylococcus aureus Peptidoglycan

Gonçalves, B. V., Portela, R., Lobo, R., Figueiredo, T. A., Grilo, I. R., Ludovice, A. M., de Lencastre, H., Dias, J. S. & Sobral, R. G., Oct 2019, In : Journal Of Clinical Microbiology. 63, 10, e00957-19.

Research output: Contribution to journal › Article

Open Access
File
2 Downloads (Pure)

First insights of peptidoglycan amidation in Gram-positive bacteria-The high-resolution crystal structure of Staphylococcus aureus glutamine amidotransferase GatD

Leisico, F., Vieira, D. V., Figueiredo, T. A., Silva, M., Cabrita, E. J., Sobral, R. G., Ludovice, A. M., Trincão, J., Romão, M. J., De Lencastre, H. & Santos-Silva, T., 1 Dec 2018, In : Scientific Reports. 8, 1, 5313.

Research output: Contribution to journal › Article

Open Access
File
    • 7 Citations (Scopus)
    28 Downloads (Pure)

    Contribution of peptidoglycan amidation to beta-lactam and lysozyme resistance in different genetic lineages of staphylococcus aureus

    Figueiredo, T. A., Ludovice, A. M. & Sobral, R. G., Jun 2014, In : Microbial Drug Resistance. 20, 3, p. 238-249 12 p.

    Research output: Contribution to journal › Article

    • 18 Citations (Scopus)

    Purification, crystallization and preliminary X-ray diffraction analysis of GatD, a glutamine amidotransferase-like protein from Staphylococcus aureus peptidoglycan

    Vieira, D., Figueiredo, T. A., Verma, A., Sobral, R. G., Ludovice, A. M., de Lencastre, H. & Trincao, J., May 2014, In : Acta Crystallographica Section F:Structural Biology Communications. 70, Part 5, p. 632-635 4 p.

    Research output: Contribution to journal › Article

    • 1 Citation (Scopus)

    The glucosaminidase domain of Atl - the major Staphylococcus aureus autolysin - has DNA-binding activity

    Grilo, I. R., Ludovice, A. M., Tomasz, A., de Lencastre, H. & Sobral, R. G., Apr 2014, In : Microbiologyopen. 3, 2, p. 247-256 10 p.

    Research output: Contribution to journal › Article

    • 13 Citations (Scopus)