Research output per year
Research output per year
Personal profile
Research interests
Microbiology and Molecular Genetics of Gram-positive bacteria. Research interests have been addressed to the understanding the regulatory networks on cell wall physiology in the methicillin-resistant Staphylococcus aureus (MRSA), that possess one of the most effective resistance mechanisms to all beta-lactam antibiotics, namely in: cell wall turnover/recycling; cell wall synthesis and division and the global cell response to the environmental stress.
Education/Academic qualification
Genetics, Doctorate, Isolamento e Caracterização de Genes da Via de Biossintética da Arginina de Streptomyces e a Sua Relação com a Produção de Ácido Clavulânico, Universidade de Lisboa
Award Date: 5 Feb 1993
Biotecnology, Master
Award Date: 3 Mar 1986
Degree in Biology
Award Date: 2 Sept 1980
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Research output
- 12 Article
-
Role of MurT C-Terminal Domain in the Amidation of Staphylococcus aureus Peptidoglycan
Gonçalves, B. V., Portela, R., Lobo, R., Figueiredo, T. A., Grilo, I. R., Ludovice, A. M., de Lencastre, H., Dias, J. S. & Sobral, R. G., Oct 2019, In: Journal Of Clinical Microbiology. 63, 10, e00957-19.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)31 Downloads (Pure) -
First insights of peptidoglycan amidation in Gram-positive bacteria-The high-resolution crystal structure of Staphylococcus aureus glutamine amidotransferase GatD
Leisico, F., Vieira, D. V., Figueiredo, T. A., Silva, M., Cabrita, E. J., Sobral, R. G., Ludovice, A. M., Trincão, J., Romão, M. J., De Lencastre, H. & Santos-Silva, T., 1 Dec 2018, In: Scientific Reports. 8, 1, 5313.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)97 Downloads (Pure) -
Contribution of peptidoglycan amidation to beta-lactam and lysozyme resistance in different genetic lineages of staphylococcus aureus
Figueiredo, T. A., Ludovice, A. M. & Sobral, R. G., Jun 2014, In: Microbial Drug Resistance. 20, 3, p. 238-249 12 p.Research output: Contribution to journal › Article › peer-review
27 Citations (Scopus) -
Purification, crystallization and preliminary X-ray diffraction analysis of GatD, a glutamine amidotransferase-like protein from Staphylococcus aureus peptidoglycan
Vieira, D., Figueiredo, T. A., Verma, A., Sobral, R. G., Ludovice, A. M., de Lencastre, H. & Trincao, J., May 2014, In: Acta Crystallographica Section F:Structural Biology Communications. 70, Part 5, p. 632-635 4 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
The glucosaminidase domain of Atl - the major Staphylococcus aureus autolysin - has DNA-binding activity
Grilo, I. R., Ludovice, A. M., Tomasz, A., de Lencastre, H. & Sobral, R. G., Apr 2014, In: Microbiologyopen. 3, 2, p. 247-256 10 p.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus)