Personal profile
Research interests
Cecília Roque is an Associate Professor with Habilitation at Departamento de Química, researcher at UCIBIO and head of the Biomolecular Engineering Lab at Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa. She holds a degree in Chemical Engineering (Major in Biotechnology) and a PhD in Biotechnology from Instituto Superior Técnico. Cecília has been a Visiting Scholar at the University of Cambridge and at the Catholic University of America, a Post-doctoral researcher at the Institute of Biotechnology (University of Cambridge) and at INESC-MN (Lisbon, Portugal). Her research focus on biotechnology, namely on the development of novel affinity receptors towards important biopharmaceuticals, as well as on the design of smart-responsive platforms for bioseparation, biosensing and biomedical applications. Cecília has been awarded the “1K Business Plan Competition” in 2001 (CEC, University of Cambridge), the “Programa de Estímulo à Investigação” in 2006 (Fundação Calouste Gulbenkian), the “Scientific Merit Award UNL-Santander Totta-Edição 2009/2010” in 2010 (Universidade Nova de Lisboa and Santander Totta Bank) and the 1st Honorable mention from SHIC´11 (by Hovione). Cecília has been recently awarded with a Starting Grant from the European Research Council (2014).
The Biomolecular Engineering Group @UCIBIO, REQUIMTE (FCT/UNL) in interface with iBET, was established in 2008 by Prof. Cecília Roque and is composed by a multidisciplinary team with expertise in Applied and Computational Chemistry, Biotechnology, Biomedical Engineering, and Chemical Engineering.
Our group is dedicated to the design and discovery of peptidomimetics with biological or synthetic backbones, and to the development of functional materials, which together find applications in Bioseparation, Biocatalysis, Sensing & Diagnostics, and Nanomedicine.
Check also our facebok page on www.facebook.com/biomenglab and stay connected on Twitter @Biomeng_lab.
Education/Academic qualification
Habilitation in Bioengineering, Bioengineering, Faculdade de Ciências e Tecnologia (FCT)
Award Date: 9 Nov 2015
Biotechnology, Doctorate, Design, Synthesis and Evaluation of Immunoglobulin Binding Ligands: An Artificial Protein L., Universidade Técnica de Lisboa
Award Date: 23 Apr 2004
Chemical Engineering-Major Biotechnology, Master, Instituto Superior Técnico
Award Date: 18 Sept 1999
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Collaborations and top research areas from the last five years
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One-Pot Synthesis of a Small Synthetic Ligand for Antibody Purification
Natal, C. M., Domingos, C., Nascimento, A., Mendes, J., Ruiz, A. B., Dias, A. M. G. C., Ferreira, L. M., Peixoto, C. & Roque, A. C. A., 6 May 2026, (Accepted/In press) In: Biotechnology and Bioengineering. p. 1-10 10 p.Research output: Contribution to journal › Article › peer-review
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Optimized pipeline for generating highly potent neutralizing Affitins: Application to SARS-CoV-2 spike protein
Maurice, T., Laporte, M., Barquilla, N., Fortun, A., Echasserieau, K., Guivel-Benhassine, F., Barbosa, A. J. M., Cossard, P., Planchais, C., Anna, F., Charneau, P., Mouquet, H., Roque, A. C. A., Schwartz, O., Mouratou, B., Davodeau, F., Bernardeau, K., Monel, B. & Pecorari, F., Jan 2026, In: International Journal of Biological Macromolecules. 336, 15 p., 149321.Research output: Contribution to journal › Article › peer-review
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Cephalopod proteins for bioinspired and sustainable biomaterials design
Lychko, I., Padrão, I., Eva, A. V., Domingos, C. A. O., Costa, H. M. A. D., Dias, A. M. G. C. & Roque, A. C. A., Apr 2025, In: Materials Today Bio. 31, 19 p., 101644.Research output: Contribution to journal › Review article › peer-review
Open AccessFile2 Link opens in a new tab Citations (Scopus)156 Downloads (Pure) -
Design and evolution of a synthetic small protein scaffold based on the WW domain
Dias, A. M. G. C., Teixeira, G. D. G., Barbosa, A. J. M., Goncalves, J., Iranzo, O. & Roque, A. C. A., Jun 2025, In: Protein Science. 34, 6, p. 1-16 16 p., e70164.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Link opens in a new tab Citations (Scopus)20 Downloads (Pure) -
Discovery and optimization of a synthetic small protein domain targeting antibodies
Dias, A. M. G. C., Matos, M. J. B., Soares, C., Natal, C., Pina, A. S. & Roque, A. C. A., 12 Nov 2025, In: Frontiers in Bioengineering and Biotechnology. 13, 1678111.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure)
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Protopeptide de basic units of reflectins: hierarcical self-assembly study in different solvents and materials properties
Dias, A. M. G. C. (Invited speaker), Moreira, I. M. P. (Speaker), Lychko, I. (Speaker), Nurrito, A. (Speaker), Moura Barbosa, A. J. (Speaker), Bueno-Lutz, V. (Speaker), Mezzenga, R. (Speaker), Marques, A. C. L. S. (Speaker), Mercês Ferreira, I. M. (Speaker), Cena, C. (Speaker), Pina, A. S. F. P. M. (Speaker) & Roque, A. C. A. (Speaker)
8 Sept 2021Activity: Talk or presentation › Oral presentation
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NOVA.ID.FCT - Associação para a Inovação e Desenvolvimento da FCT (NOVA.ID.FCT/FCTUNL/UNL) (External organisation)
Llussá, F. A. J. (Member), Roque, A. C. A. (Chair), Moura Barbosa, A. J. (Member) & Urze, P. (Member)
1 Oct 2020 → 1 Mar 2025Activity: Membership › Membership of network/project