Organization profile

Profile Information

The overarching aim of the Vector Borne-Diseases & Pathogens group is to develop and apply innovative methods for surveillance and control of vector-borne diseases. The group is implementing R&D activities on the following topics: i) vector-borne pathogens: molecular epidemiology and phylogenetics, virulence, drug resistance and new drug targets, focusing on autochthonous and vulnerable populations (i.e. migrants and travellers); ii) arthropod vectors: bioecology, systematics, evolution, population biology and insecticide resistance; iii) vector competence and vector-pathogen interactions; iv) vector monitoring, including community-based approaches; v) helminthic infections and intermediate hosts; vi) rapid, point-of-care, multi-pathogen diagnostic tools; vii) human host susceptibility; viii) risk maps.

The VBD group is part of the ZIKAlliance consortium, initiated in October 2016 and funded by the Horizon 2020 Program. The consortium involves 53 partners from Europe, America, Africa, Asia and the Pacific islands to develop clinical, epidemiological, transmission and control studies of Zika. Also noteworthy are the vector competence studies of Aedes aegypti from Madeira to ZIKV. The high rates of viral infection observed suggest that the vector is competent in the transmission of this arbovirus, reinforcing the need for vector surveillance and control in the region.

Starting from the first isogenic strain of Schistosoma mansoni resistant to Praziquantel, studies have been developed to characterize resistance mechanisms to this drug for the treatment of schistosomiasis. The results of this CNPq project suggest the involvement of efflux pumps in resistance, opening the possibility of investigating combined therapies for treatment of resistant parasites. Morphological differences were observed between resistant and sensitive parasites, which may impact the transmission and pathology of the disease.

Within the framework of the EDENext Project, the seasonal dynamics of leishmaniasis vectors in the Mediterranean were analyzed. The study involved 8 countries with transmission of L. infantum, showing that, in southernmost latitudes, the no-risk transmission period is only 4 months. This study provides a basis for the establishment of sentinel areas for the monitoring of sand-flies.

 

 

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Portugal Medicine & Life Sciences
Leishmania infantum Medicine & Life Sciences
Parasites Medicine & Life Sciences
Malaria Medicine & Life Sciences
Leishmania Medicine & Life Sciences
Culicidae Medicine & Life Sciences
Leishmaniasis Medicine & Life Sciences
Psychodidae Medicine & Life Sciences

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Research Output 2001 2019

1 Citation (Scopus)

Alternative strategies for mosquito-borne arbovirus control

Achee, N. L., John Paul, G., Vatandoost, H., Seixas, G., Pinto, J., Ng, L. C., Martins, A. J., Juntarajumnong, W., Corbel, V., Clément, G., David, J. P., James, O., James G., L., Eric, M., Gregor J., D. & John G., V., 1 Jan 2019, In : PLoS Neglected Tropical Diseases. Vol. 13, n.º 1, p. e0006822-e0006844 22 p.

Research output: Contribution to journalReview article

Open Access
Arboviruses
Culicidae
Insecticide Resistance
Public Health
Dengue

Anopheline antiplatelet protein from mosquito saliva regulates blood feeding behavior

Ashekul, I., Talha Bin, E., Daisuke S., Y., Mitsuhiro, I., Fitri, A., Yenni, Y., Ririka, Y., Shah, A., Silveira, H. & Shigeto, Y., 28 Feb 2019, p. 3129-3140. 11 p.

Research output: Contribution to conferencePaper

Feeding Behavior
Culicidae
Saliva
Proteins
Malaria

Genetic Diversity of norA, Coding for a Main Efflux Pump of Staphylococcus aureus

Costa, S. S., Sobkowiak, B., Parreira, R., Edgeworth, J. D., Viveiros, M., Clark, T. G. & Couto, I., 9 Jan 2019, In : Frontiers in Genetics. 9, p. 710-721 11 p.

Research output: Contribution to journalArticle

Open Access

Activities 2008 2016

  • 9 Publication peer-review
  • 2 Participation in workshop, seminar, course
  • 1 Editorial activity

EURNEGVEC COST Action: Training School 6

Patrícia Isabel Rosa Salgueiro (Invited speaker)
2 Jan 201630 Jan 2017

Activity: Participating in or organising an eventParticipation in workshop, seminar, course

European Journal of Entomology (Journal)

Patrícia Isabel Rosa Salgueiro (Editorial board member)
1 Jan 20161 Jun 2016

Activity: Publication peer-review and editorial workPublication peer-review

Workshop on Malaria Transmission

Patrícia Isabel Rosa Salgueiro (Invited speaker)
1 Dec 201619 Feb 2018

Activity: Participating in or organising an eventParticipation in workshop, seminar, course