Research Output 1999 2020

2018
16 Citations (Scopus)
1 Downloads (Pure)

CDG therapies: from bench to bedside

Brasil, S., Pascoal, C., Francisco, R., Marques-da-Silva, D., Andreotti, G., Videira, P. A., Morava, E., Jaeken, J. & Dos Reis Ferreira, V., 1 May 2018, In : International Journal of Molecular Sciences. 19, 5, 1304.

Research output: Contribution to journalReview article

Open Access
File
Congenital Disorders of Glycosylation
Glycosylation
seats
therapy
disorders
2 Citations (Scopus)

Cell wall glycans mediate recognition of the dairy bacterium Streptococcus thermophilus by bacteriophages

Szymczak, P., Filipe, S. R., Covas, G., Vogensen, F. K., Neves, A. R. & Janzen, T., 1 Dec 2018, In : Applied and Environmental Microbiology. 84, 23, e01847-18.

Research output: Contribution to journalArticle

Streptococcus Phages
Streptococcus thermophilus
bacteriophage
bacteriophages
Bacteriophages
15 Citations (Scopus)

Cheese whey integrated valorisation: Production, concentration and exploitation of carboxylic acids for the production of polyhydroxyalkanoates by a fed-batch culture

Domingos, J. M. B., Puccio, S., Martinez, G. A., Amaral, N., Reis, M. A. M., Bandini, S., Fava, F. & Bertin, L., 15 Mar 2018, In : Chemical Engineering Journal. 336, p. 47-53 7 p.

Research output: Contribution to journalArticle

Polyhydroxyalkanoates
Cheeses
carboxylic acid
Carboxylic Acids
Carboxylic acids
11 Citations (Scopus)

Choroid plexus is an additional source of melatonin in the brain

Quintela, T., Gonçalves, I. M. T., Silva, M., Duarte, A. C., Guedes, P., Andrade, K., Freitas, F., Talhada, D., Albuquerque, T., Tavares, S., Passarinha, L. A., Cipolla-Neto, J. & Santos, C. R. A., 1 Nov 2018, In : Journal of Pineal Research. 65, 4, e12528.

Research output: Contribution to journalArticle

Choroid Plexus
Melatonin
Brain
Cerebrospinal Fluid
Arylalkylamine N-Acetyltransferase
28 Citations (Scopus)

Chronic Kidney Disease Circulating Calciprotein Particles and Extracellular Vesicles Promote Vascular Calcification: A Role for GRP (Gla-Rich Protein)

Viegas, C. S. B., Santos, L., Macedo, A. L., Matos, A. A., Silva, A. P., Neves, P. L., Staes, A., Gevaert, K., Morais, R., Vermeer, C., Schurgers, L. & Simes, D. C., Mar 2018, In : Arteriosclerosis, thrombosis, and vascular biology. 38, 3, p. 575-587

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Co-administration of Antimicrobial Peptides Enhances Toll-like Receptor 4 Antagonist Activity of a Synthetic Glycolipid

Facchini, F. A., Coelho, H., Sestito, S. E., Delgado, S., Minotti, A., Andreu, D., Jiménez-Barbero, J. & Peri, F., 6 Feb 2018, In : Chemmedchem. 13, 3, p. 280-287 8 p.

Research output: Contribution to journalArticle

Open Access
Toll-Like Receptor 4
Glycolipids
Peptides
Lipopolysaccharides
Agglomeration
7 Downloads (Pure)
Open Access
File
Environmental Carcinogens
Carcinogens
DNA Damage
Inflammation
Epoxide Hydrolases
8 Citations (Scopus)
21 Downloads (Pure)

Combination of chemotherapy and Au-nanoparticle photothermy in the visible light to tackle doxorubicin resistance in cancer cells

Pedrosa, P., Mendes, R., Cabral, R., Martins, L. M. D. R. S., Baptista, P. V. & Fernandes, A. R., 1 Dec 2018, In : Scientific Reports. 8, 1, 11429.

Research output: Contribution to journalArticle

Open Access
File
Combination Drug Therapy
Nanoparticles
Doxorubicin
Light
Drug Therapy
11 Citations (Scopus)

Convergence of MIR-143 overexpression, oxidative stress and cell death in HCT116 human colon cancer cells

Gomes, S. E., Pereira, D. M., Roma-Rodrigues, C., Fernandes, A. R., Borralho, P. M. & Rodrigues, C. M. P., 1 Jan 2018, In : PLoS ONE. 13, 1, e0191607.

Research output: Contribution to journalArticle

Oxidative stress
Cell death
colorectal neoplasms
Colonic Neoplasms
cell death
7 Citations (Scopus)

Critical overview on the structure and metabolism of human aldehyde oxidase and its role in pharmacokinetics

Mota, C., Coelho, C., Leimkühler, S., Garattini, E., Terao, M., Santos-Silva, T. & Romão, M. J., 1 Aug 2018, In : Coordination Chemistry Reviews. 368, p. 35-59 25 p.

Research output: Contribution to journalReview article

Aldehyde Oxidase
Pharmacokinetics
oxidase
metabolism
Aldehydes
8 Citations (Scopus)

Cystobasidium alpinum sp. nov. and Rhodosporidiobolus oreadorum sp. nov. from european cold environments and arctic region

Turchetti, B., Selbmann, L., Gunde-Cimerman, N., Buzzini, P., Sampaio, J. P. & Zalar, P., 1 Jun 2018, In : Life. 8, 2, 9.

Research output: Contribution to journalArticle

Open Access
Arctic Regions
Arctic regions
yeast
Yeast
Arctic region
5 Citations (Scopus)
Open Access
Cytochrome Reductases
Cytochromes b5
Synaptic Membranes
Cell membranes
Cytochromes c
1 Citation (Scopus)

Demonstration of the ability of the bacterial polysaccharide FucoPol to flocculate kaolin suspensions

Araújo, D., Concórdio-Reis, P., Marques, A. C., Sevrin, C., Grandfils, C., Alves, V. D., Fortunato, E., Reis, M. A. M. & Freitas, F., 14 Jul 2018, (Accepted/In press) In : Environmental Technology (United Kingdom). p. 1-9 9 p.

Research output: Contribution to journalArticle

Bacterial Polysaccharides
Kaolin
Flocculation
kaolin
flocculation
4 Citations (Scopus)
Denitrification
Wastewater treatment
denitrification
oxic conditions
Phosphorus
12 Citations (Scopus)
nitrous oxide
Phosphorus
phosphorus
Oxides
electron
4 Citations (Scopus)

Design and evolution of an opto-electronic device for VOCs detection

Pádua, A. C., Palma, S., Gruber, J., Gamboa, H. & Roque, A. C., 2018, BIODEVICES 2018 - 11th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 11th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2018. Bermudez i Badia, S., Cliquet, A., Cliquet, A., Gamboa, H. & Fred, A. (eds.). SciTePress, Vol. 1. p. 48-55 8 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Volatile organic compounds
Optoelectronic devices
Optical devices
Electronic nose
Electric properties
2 Citations (Scopus)

Designing Zn(II) complexes as a support of bifunctional liquid crystal and luminescent materials

Pastor, M. J., Cuerva, C., Fernández-Lodeiro, A., Lodeiro, C., Campo, J. A. & Cano, M., 1 Feb 2018, In : Dyes and Pigments. 149, p. 37-50 14 p.

Research output: Contribution to journalArticle

Liquid Crystals
Liquid crystals
Ligands
Nitrogen
Atoms
3 Citations (Scopus)

Development and characterisation of hybrid polysaccharide membranes for dehydration processes

Meireles, I. T., Huertas, R. M., Torres, C. A. V., Coelhoso, I. M. & Crespo, J. G., 1 Jul 2018, In : Carbohydrate Polymers. 191, p. 216-224 9 p.

Research output: Contribution to journalArticle

Polysaccharides
Dehydration
Membranes
Water
Ethanol
4 Citations (Scopus)
Polystyrenes
Paraffin
Biological Assay
Paraffin Embedding
Staining and Labeling
10 Citations (Scopus)

Development of a novel target module redirecting UniCAR T cells to Sialyl Tn-expressing tumor cells

Loureiro, L. R., Feldmann, A., Bergmann, R., Koristka, S., Berndt, N., Arndt, C., Pietzsch, J., Novo, C., Videira, P. & Bachmann, M., 1 Sep 2018, In : BLOOD CANCER JOURNAL. 8, 9, 81.

Research output: Contribution to journalLetter

9 Citations (Scopus)

Development of poly-2-ethyl-2-oxazoline coated gold-core silica shell nanorods for cancer chemo-photothermal therapy

Moreira, A. F., Rodrigues, C. F., Reis, C. A., Costa, E. C., Ferreira, P. & Correia, I. J., 1 Jan 2018, In : Nanomedicine. 13, 20

Research output: Contribution to journalArticle

Nanotubes
Chemotherapy
Nanorods
Silicon Dioxide
Gold
13 Citations (Scopus)

Differential behavioural responses to venlafaxine exposure route, warming and acidification in juvenile fish (Argyrosomus regius)

Maulvault, A. L., Santos, L. H. M. L. M., Paula, J. R., Camacho, C., Pissarra, V., Fogaça, F., Barbosa, V., Alves, R., Ferreira, P. P., Barceló, D., Rodriguez-Mozaz, S., Marques, A., Diniz, M. & Rosa, R., 1 Sep 2018, In : Science of the Total Environment. 634, p. 1136-1147 12 p.

Research output: Contribution to journalArticle

Open Access
Acidification
behavioral response
Fish
acidification
warming
8 Downloads (Pure)

Dithiothreitol-based protein equalization technology to unravel biomarkers for bladder cancer

Araújo, J. E., López-Fernández, H., Diniz, M. S., Baltazar, P. M., Pinheiro, L. C., da Silva, F. C., Carrascal, M., Videira, P., Santos, H. M. & Capelo, J. L., 1 Apr 2018, In : Talanta. 180, p. 36-46 11 p.

Research output: Contribution to journalArticle

Open Access
File
Dithiothreitol
Biomarkers
Proteome
Urinary Bladder Neoplasms
Technology
6 Downloads (Pure)

Eco-friendly healing agents for recycled concrete

Garcia-Gonzalez, J., Freches, A. C., Lemos, P. C., Pereira, M. A. S., Juan-Valdes, A., Moran-del Pozo, J., Guerra-Romero, M. I. & Faria, P., Nov 2018, Proceedings of AEC 2018 - International Conference on Construction Research / Eduardo Torroja - Architecture, Engineering and Concrete. Madrid: Castineira Libreria Tecnica / Consejo Superior de Investigaciones Cientificas - Instituto de Ciencias de la Construccion Eduardo Torroja, p. 1-8 8 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
File
cement
ceramics
consolidation
replacement
water
Open Access
Enterobacter
Polysaccharides
Bacteria
Phosphates
Fucose
3 Citations (Scopus)

Engineered Protein Variants for Bioconjugation

Fernandes, C. S. M., Teixeira, G. D. G., Iranzo, O. & Roque, A. C. A., 3 Mar 2018, Biomedical Applications of Functionalized Nanomaterials: Concepts, Development and Clinical Translation. Elsevier, p. 105-138 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Amino acids
Proteins
Amino Acids
Organic Chemistry
Genetic engineering
8 Citations (Scopus)

Environmental health assessment of warming coastal ecosystems in the tropics – Application of integrative physiological indices

Madeira, C., Mendonça, V., Leal, M. C., Flores, A. A. V., Cabral, H. N., Diniz, M. S. & Vinagre, C., 1 Dec 2018, In : Science of the Total Environment. 643, p. 28-39 12 p.

Research output: Contribution to journalArticle

Tropics
Biomarkers
Ecosystems
biomarker
warming
4 Citations (Scopus)

EPR and electrochemical interpretation of bispyrazolylacetate anchored Ni(ii) and Mn(ii) complexes: cytotoxicity and anti-proliferative activity towards human cancer cell lines

Das, K., Beyene, B. B., Datta, A., Garribba, E., Roma-Rodrigues, C., Silva, A., Fernandes, A. R. & Hung, C. H., 1 Jan 2018, In : New Journal of Chemistry. 42, 11, p. 9126-9139 14 p.

Research output: Contribution to journalArticle

Cell death
Cytotoxicity
Metal ions
Paramagnetic resonance
Acetates
11 Citations (Scopus)
2 Downloads (Pure)
Open Access
File
Mononuclear Phagocyte System
E-Selectin
Immunotherapy
Dendritic Cells
Monocytes
8 Citations (Scopus)

Evaluation of cell toxicity and DNA and protein binding of green synthesized silver nanoparticles

Ribeiro, A. P. C., Anbu, S., Alegria, E. C. B. A., Fernandes, A. R., Baptista, P. V., Mendes, R., Matias, A. S., Mendes, M., Guedes da Silva, M. F. C. & Pombeiro, A. J. L., May 2018, In : Biomedicine and Pharmacotherapy. 101, p. 137-144 8 p.

Research output: Contribution to journalArticle

DNA-Binding Proteins
Silver
Nanoparticles
Inhibitory Concentration 50
Spectrum Analysis
11 Citations (Scopus)

Evidence for loss and reacquisition of alcoholic fermentation in a fructophilic yeast lineage

Gonçalves, C., Wisecaver, J. H., Kominek, J., Salema Oom, M., Leandro, M. J., Shen, X. X., Opulente, D. A., Zhou, X., Peris, D., Kurtzman, C. P., Hittinger, C. T., Rokas, A. & Gonçalves, P., 12 Apr 2018, In : eLife. 7, e33034.

Research output: Contribution to journalArticle

Yeast
Fermentation
Carbon
Yeasts
Metabolism
2 Citations (Scopus)

Explorations on the ecological role of toxin secretion and delivery in jawless predatory Polychaeta

Cuevas, N., Martins, M., Rodrigo, A. P., Martins, C. & Costa, P. M., 1 Dec 2018, In : Scientific Reports. 8, 1, 7635.

Research output: Contribution to journalArticle

Open Access
Polychaeta
Suction
Invertebrates
Thoracica
Mollusca
7 Citations (Scopus)
24 Downloads (Pure)
Open Access
File
Peptidoglycan
Gram-Positive Bacteria
Glutamine
Staphylococcus aureus
Glutaminase
1 Citation (Scopus)
Natural polymers
Acetylglucosamine
Disaccharides
Chitin
Peptidoglycan
6 Citations (Scopus)
2 Downloads (Pure)

Functional and expression analyses of the pneumocystis mat genes suggest obligate sexuality through primary homothallism within host lungs

Richard, S., Almeida, J. M. G. C. F. D., Cissé, O. H., Luraschi, A., Nielsen, O., Pagni, M. & Hauser, P. M., 1 Jan 2018, In : mBio. 9, 1, e02201-17.

Research output: Contribution to journalArticle

Open Access
File
Pneumocystis
Pneumocystis carinii
Sexuality
Lung
Reproduction
2 Citations (Scopus)

Functional redundancy ensures performance robustness in 3-stage PHA-producing mixed cultures under variable feed operation

Carvalho, G., Pedras, I., Karst, S. M., Oliveira, C. S. S., Duque, A. F., Nielsen, P. H. & Reis, M. A. M., 25 Jan 2018, In : New Biotechnology. 40, Part B, p. 207-217 11 p.

Research output: Contribution to journalConference article

Polyhydroxyalkanoates
Molasses
Cheeses
Redundancy
Cheese
Marinobacter hydrocarbonoclasticus
Marinobacter
Denitrification
Transcriptome
Gene expression

Gla-rich protein, a vitamin K-dependent protein involved in inflammation and calcification-related diseases

Viegas, C. S. B., Macedo, A. L., Matos, A. A., Neves, P. L., Silva, A. P., Vermeer, C., Schurgers, L. & Simes, D. C., 2018, In : Annals Of Medicine. 50, Suppl.1, p. S1-S2

Research output: Contribution to journalMeeting Abstract

2 Citations (Scopus)

Glycosyltransferase inhibitors: A promising strategy to pave a path from laboratory to therapy

Videira, P. A., Marcelo, F. & Grewal, R. K., 2018, Carbohydrate Chemistry: Chemical and Biological Approaches. Lindhorst, T. K., Queneau, Y. & Rauter, A. P. (eds.). Royal Society of Chemistry, p. 135-158 24 p. (Carbohydrate Chemistry; vol. 43).

Research output: Chapter in Book/Report/Conference proceedingChapter

Glycosyltransferases
Glycoside Hydrolases
Glycosylation
Therapeutics
Substrates
1 Citation (Scopus)

Gold nanoprobe-based non-crosslinking hybridization for molecular diagnostics: an update

Baptista, P. V., 2 Sep 2018, In : Expert Review Of Molecular Diagnostics. 18, 9, p. 767-773 7 p.

Research output: Contribution to journalReview article

Molecular Pathology
Gold
DNA
RNA
Miniaturization
12 Citations (Scopus)
22 Downloads (Pure)
Open Access
File
Fluorescent Dyes
Coloring Agents
Chromophores
Color
Imaging techniques
4 Citations (Scopus)

Halilectin-3, a lectin from the marine sponge Haliclona caerulea, induces apoptosis and autophagy in human breast cancer MCF7 cells through caspase-9 pathway and LC3-II protein expression

Do Nascimento-Neto, L. G., Cabral, M. G., Carneiro, R. F., Silva, Z., Arruda, F. V. S., Nagano, C. S., Fernandes, A. R., Sampaio, A. H., Teixeira, E. H. & Videira, P. A., 1 Jan 2018, In : Anti-Cancer Agents In Medicinal Chemistry. 18, 4, p. 521-528 8 p.

Research output: Contribution to journalArticle

Haliclona
Caspase 9
MCF-7 Cells
Autophagy
Porifera
1 Citation (Scopus)
8 Downloads (Pure)

Higher order scaffoldin assembly in Ruminococcus flavefaciens cellulosome is coordinated by a discrete cohesin-dockerin interaction

Bule, P., Pires, V. M. R., Alves, V. D., Carvalho, A. L., Prates, J. A. M., Ferreira, L. M. A., Smith, S. P., Gilbert, H. J., Noach, I., Bayer, E. A., Najmudin, S. & Fontes, C. M. G. A., 1 Dec 2018, In : Scientific Reports. 8, 1, 6987.

Research output: Contribution to journalArticle

Open Access
File
Cellulosomes
Ruminococcus
Rumen
Cellulose
Polysaccharides
2 Citations (Scopus)

High thermal tolerance does not protect from chronic warming – A multiple end-point approach using a tropical gastropod, Stramonita haemastoma

Madeira, C., Mendonça, V., Flores, A. A. V., Diniz, M. S. & Vinagre, C., 1 Aug 2018, In : Ecological Indicators. 91, p. 626-635 10 p.

Research output: Contribution to journalArticle

Open Access
heat tolerance
gastropod
Gastropoda
warming
tolerance
2 Citations (Scopus)
1-Naphthylamine
Chromogenics
Electrochemical sensors
Imines
Voltammetry
4 Citations (Scopus)

Important cytotoxic and cytostatic effects of new copper(i)-phosphane compounds with N,N, N,O and N,S bidentate ligands

Morais, T. S., Jousseaume, Y., Piedade, M. F. M., Roma-Rodrigues, C., Fernandes, A. R., Marques, F., Villa De Brito, M. J. & Helena Garcia, M., 1 Jan 2018, In : Dalton Transactions. 47, 23, p. 7819-7829 11 p.

Research output: Contribution to journalArticle

phosphine
Cytostatic Agents
Copper
Bearings (structural)
Cells
15 Citations (Scopus)
Ductal Carcinoma
E-Selectin
p38 Mitogen-Activated Protein Kinases
Cell Proliferation
Ligands
3 Citations (Scopus)
2 Downloads (Pure)

In silico HCT116 human colon cancer cell-based models en route to the discovery of lead-like anticancer drugs

Cruz, S., Gomes, S. E., Borralho, P. M., Rodrigues, C. M. P., Gaudêncio, S. P. & Pereira, F., 1 Sep 2018, In : Biomolecules. 8, 3, 56.

Research output: Contribution to journalArticle

Open Access
File
Computer Simulation
Colonic Neoplasms
Magnetic Resonance Spectroscopy
Biological Products
Cells
11 Citations (Scopus)

Integrated multi-biomarker responses of juvenile seabass to diclofenac, warming and acidification co-exposure

Maulvault, A. L., Barbosa, V., Alves, R., Anacleto, P., Camacho, C., Cunha, S., Fernandes, J. O., Ferreira, P. P., Rosa, R., Marques, A. & Diniz, M., 1 Sep 2018, In : Aquatic Toxicology. 202, p. 65-79 15 p.

Research output: Contribution to journalArticle

Open Access
Diclofenac
acidification
biomarker
biomarkers
warming