Comprehensive Health Research Centre (CHRC) is a new, national, centre of excellence for research, training and innovation in health promotion, prevention, rehabilitation and healthcare services. This consortium is composed by healthcare professionals, researchers, academics, patients and entrepreneurs who work together towards a common goal. CHRC provides a unifying environment for innovation and education in public health, lifestyles, nursing, rehabilitation and clinical research. CHRC integrates researchers from different institutions with distinct backgrounds and skills committed to the same goal: improving health and wellbeing of individuals and populations. This strategy must engage citizens and population, increase literacy, and stimulate co-creation in a bottom-up process of problem-solving.