Centro de Investigação em Genética Molecular Humana (CIGMH)

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Unspliced Precursors of NMD-Sensitive β-Globin Transcripts Exhibit Decreased Steady-State Levels in Erythroid Cells.

Morgado, A., Almeida, F., Teixeira, A., Silva, A. L. & Romão, L., 1 Jan 2012, In : PLoS ONE. 7, 6, p. Online

Research output: Contribution to journalArticle

Open Access
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3 Citations (Scopus)
1 Downloads (Pure)

Translocation (8;17;15;21)(q22;q23;q15;q22) in acute myeloid leukemia (M2): A four-way variant of t(8;21)

Vieira, L., Oliveira, V., Ambrósio, A. P., Marques, B., Pereira, A. M., Hagemeijer, A. & Boavida, M. G., 15 Jul 2001, In : Cancer Genetics And Cytogenetics. 128, 2, p. 104-107 4 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

The spectrum of mutations and molecular pathogenesis of hemophilia A in 181 Portuguese patients

David, D., Ventura, C., Moreira, I., Diniz, M. J., Antunes, M., Tavares, A., Araújo, F., Morais, S., Campos, M., Lavinha, J. & Kemball-Cook, G., 2006, In : Haematologica. 91, 6, p. 840-843 4 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

The chemistry and biology of gold nanoparticle-mediated photothermal therapy: promises and challenges

Baptista, P. M. R. V., 1 Jan 2013, In : Nano LIFE. 03, 03, p. nr. 1330001

Research output: Contribution to journalArticle

Open Access

Tc-99m-Tricarbonyl Complexes Functionalized with Anthracenyl Fragments: Synthesis, Characterization, and Evaluation of Their Radiotoxic Effects in Murine Melanoma Cells

Vitor, RF., Esteves, T., Marques, F., Raposinho, P., Paulo, A., Rodrigues, A. S., Rueff, J., Casimiro, S., Costa, L. & Santos, I., 1 Oct 2009, In : Cancer biotherapy & radiopharmaceuticals. 24, 5, p. 551-563 13 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
13 Citations (Scopus)

Synthesis, characterization and cytotoxic activity of gallium(III) complexes anchored by tridentate pyrazole-based ligands

Silva, F., Marques, F., Santos, I. C., Paulo, A., Rodrigues, A. S., Rueff, J. & Santos, I., 1 Jan 2010, In : Journal of Inorganic Biochemistry. 104, 5, p. 523-532

Research output: Contribution to journalArticle

22 Citations (Scopus)

Star-shaped magnetite@gold nanoparticles for protein magnetic separation and SERS detection

Quaresma, P., Osório, I., Dória, G., Carvalho, P. A., Pereira, A., Langer, J., Araújo, J. P., Pastoriza-Santos, I., Liz-Marzán, L. M., Franco, R., Baptista, P. & Pereira, E., 2014, In : RCS Advances. 4, 8, p. 3659-3667 9 p.

Research output: Contribution to journalArticle

62 Citations (Scopus)

Single Nucleotide Polymorphism Detection Using Gold Nanoprobes and Bio-Microfluidic Platform With Embedded Microlenses

Bernacka-Wojcik, I., Aguas, H., Carlos, F. F., Lopes, P., Wojcik, P. J., Costa, M. N., Veigas, B., Igreja, R., Fortunato, E., Baptista, P. & Martins, R., 10 Mar 2015, In : Biotechnology and Bioengineering. 112, 6, p. 1210-1219 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Resistance of mRNAs with AUG-proximal nonsense mutations to nonsense-mediated decay reflects variables of mRNA structure and translational activity

Pereira, F. J. C., Teixeira, A. R. S., Kong, J., Barbosa, C., Silva, A. L., Marques-Ramos, A., Liebhaber, S. A. & Romão, L., 23 May 2015, In : Nucleic Acids Research. 43, 13, p. 6528-6544 17 p.

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Open Access
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16 Citations (Scopus)
2 Downloads (Pure)

Protective role of ortho-substituted Mn(III) N-alkylpyridylporphyrins against the oxidative injury induced by tert-butylhydroperoxide

Fernandes, A. S., Gaspar, J., Cabral, M. F., Rueff, J., Castro, M., Batinic-Haberle, I., Costa, J. & Oliveira, N. G., 19 Mar 2010, In : Free Radical Research. 44, 4, p. 430-440 11 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Prognostic value of microRNA-203a expression in breast cancer

Gomes, B. C., Martins, M., Lopes, P., Morujão, I., Oliveira, M., Araújo, A., Rueff, J. & Rodrigues, AS., 1 Sep 2016, In : Oncology Reports. 36, 3, p. 1748-1756 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Preface

Rueff, J. & Rodrigues, AS., 2016, In : Methods In Molecular Biology (Clifton, N.J.). 1395, p. v-vii

Research output: Contribution to journalArticle

Predominance of constitutional chromosomal rearrangements in human chromosomal fragile sites

Sequeira, I. J. D. S., Mexia, J. T. P. N., Santiago, J., Mamede, R., Silva, E., Santos, J., Faria, D., Rueff, J. & Brás, A., 1 Jan 2013, In : Open Journal of Genetics. 3, NA, p. 8-13

Research output: Contribution to journalArticle

Open Access
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Polyurea dendrimer for efficient cytosolic siRNA delivery

Cidade, M. T. V. & Baptista, P., 1 Jan 2014, In : RSC ADVANCES. 4, 97, p. 54872-54878

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)
14 Citations (Scopus)
25 Citations (Scopus)
3 Citations (Scopus)

Nanoparticle Drug Delivery Systems: Recent Patents and Applications in Nanomedicine

Martins, P., Rosa, D., Fernandes, A. R. & Baptista, P., Jan 2013, In : Recent Patents on Nanomedicine. 3, 2, p. 105-118 14 p.

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)

Mutagenic effects of poly (ADP-ribose) polymerase-1 deficiency in transgenic mice

Louro, H., Pinheiro, I., Costa, P., Sousa, C., Dias, A., Boavida, M. G. & Silva, M. J., 2 Apr 2008, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 640, 1-2, p. 82-88 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
6 Citations (Scopus)

Mutagenic activity of cisplatin in the lacZ plasmid-based transgenic mouse model

Louro, H., Silva, M. J. & Boavida, M. G., 1 Dec 2002, In : Environmental And Molecular Mutagenesis. 40, 4, p. 283-291 9 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Multifunctional gold nanoparticles for gene silencing

Baptista, P. M. R. V., 1 Jan 2012, In : Abstracts Of Papers Of The American Chemical Society. 243, NA, p. -

Research output: Contribution to journalArticle

Molecular cytogenetic characterization of rearrangements involving 12p in leukemia

Vieira, L., Marques, B., Cavaleiro, C., Ambrósio, A. P., Jorge, M., Neto, A., Costa, J. M., Júnior, E. C. & Boavida, M. G., 2005, In : Cancer Genetics And Cytogenetics. 157, 2, p. 134-139 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

MicroRNAs and Cancer Drug Resistance

Gomes, B. C., Rueff, J. & Rodrigues, A. S., 2016, In : Methods In Molecular Biology (Clifton, N.J.). 1395, p. 137-62 26 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Macrocyclic copper(II) complexes: Superoxide scavenging activity, structural studies and cytotoxicity evaluation

Fernandes, A. S., Gaspar, J., Cabral, M. F., Caneiras, C., Guedes, R., Rueff, J., Castro, M., Costa, J. & Oliveira, N. G., 1 May 2007, In : Journal of Inorganic Biochemistry. 101, 5, p. 849-858 10 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)
Open Access
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22 Citations (Scopus)
Open Access
27 Citations (Scopus)
98 Citations (Scopus)
2 Citations (Scopus)

Instability of the human cytochrome P450 reductase A287P variant is the major contributor to its Antley-Bixler syndrome-like phenotype

McCammon, K. M., Panda, S. P., Xia, C., Kim, J. J. P., Moutinho, D., Kranendonk, M., Auchus, R. J., Lafer, E. M., Ghosh, D., Martasek, P., Kar, R., Masters, B. S. & Roman, L. J., 23 Sep 2016, In : Journal of Biological Chemistry. 291, 39, p. 20487-20502 16 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
27 Citations (Scopus)

Insights into the mechanisms underlying the antiproliferative potential of a Co(II) coordination compound bearing 1,10-phenanthroline-5,6-dione: DNA and protein interaction studies

Luis, DV., Silva, J., Tomaz, AI., de Almeida, RFM., Larguinho, M., Baptista, P. V., Martins, LMDRS., Silva, TFS., Borralho, PM., Rodrigues, CMP., Rodrigues, A. S., Pombeiro, AJL. & Fernandes, A. R., 1 Jan 2014, In : Journal Of Biological Inorganic Chemistry. 19, 6, p. 787-803

Research output: Contribution to journalArticle

24 Citations (Scopus)

Insertion of the 5' part of BCR within the ABL gene at 9q34 in a Philadelphia-negative chronic myeloid leukemia

Vieira, L., Alves, A. C., Marques, B., Reis, I., Jorge, G., Ambrósio, A. P., De Sousa, A. B. & Boavida, M. G., 1 Oct 1999, In : Cancer Genetics And Cytogenetics. 114, 1, p. 17-21 5 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
11 Citations (Scopus)

Increased levels of sister chromatid exchanges in military aircraft pilots

Silva, M. J., Carothers, A., Castelo Branco, N., Dias, A. & Boavida, M. G., 26 Apr 1999, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 441, 1, p. 129-134 6 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
4 Citations (Scopus)

Human exposure to indoor radon: a survey in the region of Guarda, Portugal

Louro, A., Peralta, L., Soares, S., Pereira, A., Cunha, G., Belchior, A., Ferreira, L., Gil, OM., Louro, H., Pinto, P., Rodrigues, A. S., Silva, MJ. & Teles, P., 2013, In : Radiation Protection Dosimetry. 154, 2, p. 237-244

Research output: Contribution to journalArticle

4 Citations (Scopus)

Human Cytochrome P450 Oxidoreductase Deficiency Caused by the Y181D Mutation: Molecular Consequences and Rescue of Defect

Marohnic, C. C., Panda, S. P., McCammon, K. M., Rueff, J., Masters, B. S. S. & Kranendonk, M., 1 Jan 2010, In : Drug Metabolism And Disposition. 38, 2, p. 332-340

Research output: Contribution to journalArticle

Open Access
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40 Citations (Scopus)
12 Downloads (Pure)

Gold nanoprobes for multi loci assessment of multi-drug resistant tuberculosis

Pedrosa, P., Veigas, B., Machado, D., Couto, I., Viveiros, M. & Baptista, P., May 2014, In : Tuberculosis. 94, 3, p. 332-337 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Gold nanoparticle-siRNA mediated oncogene knockdown at RNA and protein level, with associated gene effects

Child, H. W., Hernandez, Y., Conde, J., Mullin, M., Baptista, P., Maria de la Fuente, J. & Berry, C. C., 2015, In : Nanomedicine. 10, 16, p. 2513-2525 13 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Gold nanoparticles for the development of clinical diagnosis methods

Baptista, P. M. R. V. & Franco, R., 1 Jan 2008, In : Analytical and Bioanalytical Chemistry. 391, 3, p. 943-950

Research output: Contribution to journalArticle

Open Access
354 Citations (Scopus)

Gold nanoparticles for the development of clinical diagnosis methods

Baptista, P. M. R. V. & Franco, R., 1 Jan 2008, In : Analytical and Bioanalytical Chemistry. 391, 3, p. 943-950

Research output: Contribution to journalArticle

Open Access
354 Citations (Scopus)
Open Access
48 Citations (Scopus)