Centro de Investigação em Genética Molecular Humana (CIGMH)

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Absence of stimulation of poly(ADP-ribose) polymerase activity in patients predisposed to colon cancer

Cristóvão, L., Lechner, M. C., Fidalgo, P., Leitão, C. N., Mira, F. C. & Rueff, J., 1 Jan 1998, In : British Journal of Cancer. 77, 10, p. 1628-1632 5 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

ACMA (9-amino-6-chloro-2-methoxy acridine) forms three complexes in the presence of DNA

Busto, N., García, B., Leal, J. M., Gaspar, J. F., Martins, C., Boggioni, A. & Secco, F., 21 Nov 2011, In : Physical Chemistry Chemical Physics. 13, 43, p. 19534-19545 12 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
109 Citations (Scopus)

Altered Human CYP3A4 Activity Caused by Antley-Bixler Syndrome-Related Variants of NADPH-Cytochrome P450 Oxidoreductase Measured in a Robust In Vitro System

Moutinho, D., Marohnic, C. C., Panda, S. P., Rueff, J., Masters, B. S. S. S. S. & Kranendonk, M., Apr 2012, In : Drug Metabolism And Disposition. 40, 4, p. 754-760 7 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
Open Access
41 Citations (Scopus)

Analysis of Pelagia noctiluca proteome Reveals a Red Fluorescent Protein, a Zinc Metalloproteinase and a Peroxiredoxin

Frazao, B., Campos, A., Osorio, H., Thomas, B., Leandro, S., Teixeira, A., Vasconcelos, V. & Antunes, A., Apr 2017, In : Protein Journal. 36, 2, p. 77-97 11 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Antibody-drug gold nanoantennas with Raman spectroscopic fingerprints for in vivo tumour theranostics

Conde, J., Bao, C., Cui, D., Baptista, P. & Tian, F., 10 Jun 2014, In : Journal Of Controlled Release. 183, p. 87-93 7 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

A promising road with challenges: where are gold nanoparticles in translational research?

Bao, C., Conde, J., Polo, E., del Pino, P., Moros, M., Baptista, P., Grazu, V., Cui, D. & de la Fuente, J. M., 2014, In : Nanomedicine. 9, 15, p. 2353-2370 18 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)
17 Citations (Scopus)

Characterization of genomic single nucleotide polymorphism via colorimetric detection using a single gold nanoprobe

Carlos, F. F., Flores, O., Doria, G. & Baptista, P., 15 Nov 2014, In : Analytical Biochemistry. 465, p. 1-5 5 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Chitosan mouthwash: Toxicity and in vivo validation

Costa, E. M., Silva, S., Costa, M. R., Pereira, M., Campos, D. A., Odila, J., Madureira, A. R., Cardelle-Cobas, A., Tavaria, F. K., Rodrigues, A. S. & Pintado, M. M., 2014, In : Carbohydrate Polymers. 111, NA, p. 385-392 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Colorimetric detection of eukaryotic gene expression with DNA-derivatized gold nanoparticles

Baptista, P. M. R. V., Dória, G., Henriques, D., Pereira, E. & Franco, R., 1 Jan 2005, In : Journal of Biotechnology. 119, 2, p. 111-7 7 p.

Research output: Contribution to journalArticle

Open Access
91 Citations (Scopus)

Combined molecular diagnosis of b-cell lymphomas with t(11;14)(q13;q32) or t(14;18)(q32;q21) using multiplex- and long distance inverse-polymerase chain reaction

Vieira, L., Martinho, A., Antunes, O., Silva, E., Ambrósio, A. P., Geraldes, M. C., Nascimento, R., Silva, C., Pereira, J. M., Júnior, E. C. & Jordan, P., 1 Jun 2008, In : Diagnostic Molecular Pathology. 17, 2, p. 73-81 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Comparative analysis of the mutagenic activity of oxaliplatin and cisplatin in the Hprt gene of CHO cells

Silva, M. J., Costa, P., Dias, A., Valente, M., Louro, H. & Boavida, M. G., 1 Aug 2005, In : Environmental And Molecular Mutagenesis. 46, 2, p. 104-115 12 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)
19 Citations (Scopus)

Detection and quantitative analysis of human herpesvirus in pilocytic astrocytoma

Neves, A. M., Thompson, G., Carvalheira, J., Trindade, J. C., Rueff, J., Caetano, J. M., Casey, J. W. & Hermouet, S., 24 Jul 2008, In : Brain Research. 1221, p. 108-114 7 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Development of a fast and efficient ultrasonic-based strategy for DNA fragmentation

Larguinho, M., Santos, H. M., Doria, G., Scholz, H., Baptista, P. V. & Capelo, J. L., 15 May 2010, In : Talanta. 81, 3, p. 881-886 6 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
43 Citations (Scopus)

DNA damage response in imatinib resistant chronic myeloid leukemia K562 cells.

Dinis, J., Silva, V., Gromicho, M., Martins, C., Laires, A., Tavares, P., Rendeiro, P., Torres, F., Rueff, J. & Rodrigues, AS., 2012, In : Leukemia & Lymphoma. 53, 10, p. 2004-14 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
Open Access
27 Citations (Scopus)
Open Access
21 Citations (Scopus)

Estragole: A weak direct-acting food-borne genotoxin and potential carcinogen

Martins, C., Cação, R., Cole, K. J., Phillips, D. H., Laires, A., Rueff, J. & Rodrigues, A. S., 2012, In : Mutation Research-Genetic Toxicology And Environmental Mutagenesis. 747, 1, p. 86-92 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Evidence of one-way flow bioaccumulation of gold nanoparticles across two trophic levels

Larguinho, M., Correia, D., Diniz, M. & Baptista, P., 15 Jul 2014, In : Journal Of Nanoparticle Research. 16, 8, 11 p., 2549.

Research output: Contribution to journalArticle

24 Citations (Scopus)
5 Citations (Scopus)

Functional characterization of eight human CYP1A2 variants: The role of cytochrome b5

Palma, B. B., Silva E Sousa, M., Urban, P., Rueff, J. & Kranendonk, M., 1 Feb 2013, In : Pharmacogenetics And Genomics. 23, 2, p. 41-52 12 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
1 Citation (Scopus)

Genomics and Cancer Drug Resistance

Rodrigues, A. S., Dinis, J., Gromicho, M., Martins, C., Laires, A. & Rueff, J., 1 Jan 2012, In : Current Pharmaceutical Biotechnology. 13, 5, p. 651-673

Research output: Contribution to journalArticle

32 Citations (Scopus)
24 Citations (Scopus)
5 Citations (Scopus)

Gold and silver nanoparticles for clinical diagnostics - From genomics to proteomics.

Baptista, P. M. R. V., 1 Jan 2011, In : Journal of Proteomics. 75, NA, p. 2811-23

Research output: Contribution to journalArticle

Open Access
122 Citations (Scopus)
Open Access
71 Citations (Scopus)
Open Access
48 Citations (Scopus)

Gold nanoparticles for the development of clinical diagnosis methods

Baptista, P. M. R. V. & Franco, R., 1 Jan 2008, In : Analytical and Bioanalytical Chemistry. 391, 3, p. 943-950

Research output: Contribution to journalArticle

Open Access
355 Citations (Scopus)

Gold nanoparticles for the development of clinical diagnosis methods

Baptista, P. M. R. V. & Franco, R., 1 Jan 2008, In : Analytical and Bioanalytical Chemistry. 391, 3, p. 943-950

Research output: Contribution to journalArticle

Open Access
355 Citations (Scopus)

Gold nanoparticle-siRNA mediated oncogene knockdown at RNA and protein level, with associated gene effects

Child, H. W., Hernandez, Y., Conde, J., Mullin, M., Baptista, P., Maria de la Fuente, J. & Berry, C. C., 2015, In : Nanomedicine. 10, 16, p. 2513-2525 13 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Gold nanoprobes for multi loci assessment of multi-drug resistant tuberculosis

Pedrosa, P., Veigas, B., Machado, D., Couto, I., Viveiros, M. & Baptista, P., May 2014, In : Tuberculosis. 94, 3, p. 332-337 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Human Cytochrome P450 Oxidoreductase Deficiency Caused by the Y181D Mutation: Molecular Consequences and Rescue of Defect

Marohnic, C. C., Panda, S. P., McCammon, K. M., Rueff, J., Masters, B. S. S. & Kranendonk, M., 1 Jan 2010, In : Drug Metabolism And Disposition. 38, 2, p. 332-340

Research output: Contribution to journalArticle

Open Access
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41 Citations (Scopus)
12 Downloads (Pure)

Human exposure to indoor radon: a survey in the region of Guarda, Portugal

Louro, A., Peralta, L., Soares, S., Pereira, A., Cunha, G., Belchior, A., Ferreira, L., Gil, OM., Louro, H., Pinto, P., Rodrigues, A. S., Silva, MJ. & Teles, P., 2013, In : Radiation Protection Dosimetry. 154, 2, p. 237-244

Research output: Contribution to journalArticle

4 Citations (Scopus)
4 Citations (Scopus)

Increased levels of sister chromatid exchanges in military aircraft pilots

Silva, M. J., Carothers, A., Castelo Branco, N., Dias, A. & Boavida, M. G., 26 Apr 1999, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 441, 1, p. 129-134 6 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
11 Citations (Scopus)

Insertion of the 5' part of BCR within the ABL gene at 9q34 in a Philadelphia-negative chronic myeloid leukemia

Vieira, L., Alves, A. C., Marques, B., Reis, I., Jorge, G., Ambrósio, A. P., De Sousa, A. B. & Boavida, M. G., 1 Oct 1999, In : Cancer Genetics And Cytogenetics. 114, 1, p. 17-21 5 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Insights into the mechanisms underlying the antiproliferative potential of a Co(II) coordination compound bearing 1,10-phenanthroline-5,6-dione: DNA and protein interaction studies

Luis, DV., Silva, J., Tomaz, AI., de Almeida, RFM., Larguinho, M., Baptista, P. V., Martins, LMDRS., Silva, TFS., Borralho, PM., Rodrigues, CMP., Rodrigues, A. S., Pombeiro, AJL. & Fernandes, A. R., 1 Jan 2014, In : Journal Of Biological Inorganic Chemistry. 19, 6, p. 787-803

Research output: Contribution to journalArticle

24 Citations (Scopus)