Centro de Investigação em Genética Molecular Humana (CIGMH)

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Article
2012

Genomics and Cancer Drug Resistance

Rodrigues, A. S., Dinis, J., Gromicho, M., Martins, C., Laires, A. & Rueff, J., 1 Jan 2012, In : Current Pharmaceutical Biotechnology. 13, 5, p. 651-673

Research output: Contribution to journalArticle

32 Citations (Scopus)
Open Access
48 Citations (Scopus)

Multifunctional gold nanoparticles for gene silencing

Baptista, P. M. R. V., 1 Jan 2012, In : Abstracts Of Papers Of The American Chemical Society. 243, NA, p. -

Research output: Contribution to journalArticle

Unspliced Precursors of NMD-Sensitive β-Globin Transcripts Exhibit Decreased Steady-State Levels in Erythroid Cells.

Morgado, A., Almeida, F., Teixeira, A., Silva, A. L. & Romão, L., 1 Jan 2012, In : PLoS ONE. 7, 6, p. Online

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
1 Downloads (Pure)
2011

ACMA (9-amino-6-chloro-2-methoxy acridine) forms three complexes in the presence of DNA

Busto, N., García, B., Leal, J. M., Gaspar, J. F., Martins, C., Boggioni, A. & Secco, F., 21 Nov 2011, In : Physical Chemistry Chemical Physics. 13, 43, p. 19534-19545 12 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
45 Citations (Scopus)
24 Citations (Scopus)

Gold and silver nanoparticles for clinical diagnostics - From genomics to proteomics.

Baptista, P. M. R. V., 1 Jan 2011, In : Journal of Proteomics. 75, NA, p. 2811-23

Research output: Contribution to journalArticle

Open Access
124 Citations (Scopus)
26 Citations (Scopus)
13 Citations (Scopus)
2010

Development of a fast and efficient ultrasonic-based strategy for DNA fragmentation

Larguinho, M., Santos, H. M., Doria, G., Scholz, H., Baptista, P. V. & Capelo, J. L., 15 May 2010, In : Talanta. 81, 3, p. 881-886 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Human Cytochrome P450 Oxidoreductase Deficiency Caused by the Y181D Mutation: Molecular Consequences and Rescue of Defect

Marohnic, C. C., Panda, S. P., McCammon, K. M., Rueff, J., Masters, B. S. S. & Kranendonk, M., 1 Jan 2010, In : Drug Metabolism And Disposition. 38, 2, p. 332-340

Research output: Contribution to journalArticle

Open Access
File
42 Citations (Scopus)
18 Downloads (Pure)
3 Citations (Scopus)
14 Citations (Scopus)

Protective role of ortho-substituted Mn(III) N-alkylpyridylporphyrins against the oxidative injury induced by tert-butylhydroperoxide

Fernandes, A. S., Gaspar, J., Cabral, M. F., Rueff, J., Castro, M., Batinic-Haberle, I., Costa, J. & Oliveira, N. G., 19 Mar 2010, In : Free Radical Research. 44, 4, p. 430-440 11 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Synthesis, characterization and cytotoxic activity of gallium(III) complexes anchored by tridentate pyrazole-based ligands

Silva, F., Marques, F., Santos, I. C., Paulo, A., Rodrigues, A. S., Rueff, J. & Santos, I., 1 Jan 2010, In : Journal of Inorganic Biochemistry. 104, 5, p. 523-532

Research output: Contribution to journalArticle

23 Citations (Scopus)
2009
19 Citations (Scopus)

Tc-99m-Tricarbonyl Complexes Functionalized with Anthracenyl Fragments: Synthesis, Characterization, and Evaluation of Their Radiotoxic Effects in Murine Melanoma Cells

Vitor, RF., Esteves, T., Marques, F., Raposinho, P., Paulo, A., Rodrigues, A. S., Rueff, J., Casimiro, S., Costa, L. & Santos, I., 1 Oct 2009, In : Cancer biotherapy & radiopharmaceuticals. 24, 5, p. 551-563 13 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Combined molecular diagnosis of b-cell lymphomas with t(11;14)(q13;q32) or t(14;18)(q32;q21) using multiplex- and long distance inverse-polymerase chain reaction

Vieira, L., Martinho, A., Antunes, O., Silva, E., Ambrósio, A. P., Geraldes, M. C., Nascimento, R., Silva, C., Pereira, J. M., Júnior, E. C. & Jordan, P., 1 Jun 2008, In : Diagnostic Molecular Pathology. 17, 2, p. 73-81 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Detection and quantitative analysis of human herpesvirus in pilocytic astrocytoma

Neves, A. M., Thompson, G., Carvalheira, J., Trindade, J. C., Rueff, J., Caetano, J. M., Casey, J. W. & Hermouet, S., 24 Jul 2008, In : Brain Research. 1221, p. 108-114 7 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Gold nanoparticles for the development of clinical diagnosis methods

Baptista, P. M. R. V. & Franco, R., 1 Jan 2008, In : Analytical and Bioanalytical Chemistry. 391, 3, p. 943-950

Research output: Contribution to journalArticle

Open Access
360 Citations (Scopus)

Gold nanoparticles for the development of clinical diagnosis methods

Baptista, P. M. R. V. & Franco, R., 1 Jan 2008, In : Analytical and Bioanalytical Chemistry. 391, 3, p. 943-950

Research output: Contribution to journalArticle

Open Access
360 Citations (Scopus)

Mutagenic effects of poly (ADP-ribose) polymerase-1 deficiency in transgenic mice

Louro, H., Pinheiro, I., Costa, P., Sousa, C., Dias, A., Boavida, M. G. & Silva, M. J., 2 Apr 2008, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 640, 1-2, p. 82-88 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2007
Open Access
41 Citations (Scopus)

Macrocyclic copper(II) complexes: Superoxide scavenging activity, structural studies and cytotoxicity evaluation

Fernandes, A. S., Gaspar, J., Cabral, M. F., Caneiras, C., Guedes, R., Rueff, J., Castro, M., Costa, J. & Oliveira, N. G., 1 May 2007, In : Journal of Inorganic Biochemistry. 101, 5, p. 849-858 10 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)
2006

The spectrum of mutations and molecular pathogenesis of hemophilia A in 181 Portuguese patients

David, D., Ventura, C., Moreira, I., Diniz, M. J., Antunes, M., Tavares, A., Araújo, F., Morais, S., Campos, M., Lavinha, J. & Kemball-Cook, G., 2006, In : Haematologica. 91, 6, p. 840-843 4 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2005

Colorimetric detection of eukaryotic gene expression with DNA-derivatized gold nanoparticles

Baptista, P. M. R. V., Dória, G., Henriques, D., Pereira, E. & Franco, R., 1 Jan 2005, In : Journal of Biotechnology. 119, 2, p. 111-7 7 p.

Research output: Contribution to journalArticle

Open Access
92 Citations (Scopus)

Comparative analysis of the mutagenic activity of oxaliplatin and cisplatin in the Hprt gene of CHO cells

Silva, M. J., Costa, P., Dias, A., Valente, M., Louro, H. & Boavida, M. G., 1 Aug 2005, In : Environmental And Molecular Mutagenesis. 46, 2, p. 104-115 12 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Molecular cytogenetic characterization of rearrangements involving 12p in leukemia

Vieira, L., Marques, B., Cavaleiro, C., Ambrósio, A. P., Jorge, M., Neto, A., Costa, J. M., Júnior, E. C. & Boavida, M. G., 2005, In : Cancer Genetics And Cytogenetics. 157, 2, p. 134-139 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2002

Mutagenic activity of cisplatin in the lacZ plasmid-based transgenic mouse model

Louro, H., Silva, M. J. & Boavida, M. G., 1 Dec 2002, In : Environmental And Molecular Mutagenesis. 40, 4, p. 283-291 9 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2001

Translocation (8;17;15;21)(q22;q23;q15;q22) in acute myeloid leukemia (M2): A four-way variant of t(8;21)

Vieira, L., Oliveira, V., Ambrósio, A. P., Marques, B., Pereira, A. M., Hagemeijer, A. & Boavida, M. G., 15 Jul 2001, In : Cancer Genetics And Cytogenetics. 128, 2, p. 104-107 4 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
1999

Increased levels of sister chromatid exchanges in military aircraft pilots

Silva, M. J., Carothers, A., Castelo Branco, N., Dias, A. & Boavida, M. G., 26 Apr 1999, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 441, 1, p. 129-134 6 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Insertion of the 5' part of BCR within the ABL gene at 9q34 in a Philadelphia-negative chronic myeloid leukemia

Vieira, L., Alves, A. C., Marques, B., Reis, I., Jorge, G., Ambrósio, A. P., De Sousa, A. B. & Boavida, M. G., 1 Oct 1999, In : Cancer Genetics And Cytogenetics. 114, 1, p. 17-21 5 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
1998

Absence of stimulation of poly(ADP-ribose) polymerase activity in patients predisposed to colon cancer

Cristóvão, L., Lechner, M. C., Fidalgo, P., Leitão, C. N., Mira, F. C. & Rueff, J., 1 Jan 1998, In : British Journal of Cancer. 77, 10, p. 1628-1632 5 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
1996
6 Citations (Scopus)
1994
5 Citations (Scopus)