• Portugal

Research Output 1994 2019

2019
1 Citation (Scopus)

Accurate Determination of Human CPR Conformational Equilibrium by smFRET using Dual Orthogonal Non-Canonical Amino Acid Labeling

Quast, R. B., Fatemi, F., Kranendonk, M., Margeat, E. & Truan, G., Mar 2019, In : Chembiochem. 20, 5, p. 659-666

Research output: Contribution to journalArticle

NADPH-Ferrihemoprotein Reductase
Energy Transfer
Energy transfer
Labeling
Coloring Agents

A multi-endpoint approach to the combined toxic effects of patulin and ochratoxin a in human intestinal cells

Assunção, R., Pinhão, M., Loureiro, S., Alvito, P. & Silva, M. J., 1 Oct 2019, In : Toxicology Letters. 313, p. 120-129 10 p.

Research output: Contribution to journalArticle

Patulin
Ochratoxins
Mycotoxins
Poisons
Cytotoxicity
Microsomes
Salmonella
Toxicology
Mutation
Research

Biological impact of metal nanomaterials in relation to their physicochemical characteristics

Louro, H., Saruga, A., Santos, J., Pinhão, M. & Silva, M. J., 1 Apr 2019, In : Toxicology In Vitro. 56, p. 172-183 12 p.

Research output: Contribution to journalArticle

Nanostructures
Nanostructured materials
Metals
corrigendum
In Vitro Techniques

Extraction of tomato by-products’ bioactive compounds using ohmic technology

Coelho, M., Pereira, R., Rodrigues, A. S., Teixeira, J. A. & Pintado, M. E., 1 Sep 2019, In : Food and Bioproducts Processing. 117, p. 329-339 11 p.

Research output: Contribution to journalArticle

Lycopersicon esculentum
byproducts
Byproducts
ohmic heating
tomatoes

Genotypic differences between southwestern Europe and Africa: a comparative study in eNOS, G6PD, GSTM1 and GSTTI genes

Aguiar, L., Semente, I., Carvalho, A., Caroca, C., Caria, H., Faustino, P., Bicho, M. & Inacio, A., Jun 2019, In : Hiv Medicine. 98, 26

Research output: Contribution to journalMeeting Abstract

Human biomonitoring in health risk assessment in Europe: Current practices and recommendations for the future

Louro, H., Heinälä, M., Bessems, J., Buekers, J., Vermeire, T., Woutersen, M., van Engelen, J., Borges, T., Rousselle, C., Ougier, E., Alvito, P., Martins, C., Assunção, R., Silva, M. J., Pronk, A., Schaddelee-Scholten, B., Del Carmen Gonzalez, M., de Alba, M., Castaño, A., Viegas, S. & 7 othersHumar-Juric, T., Kononenko, L., Lampen, A., Vinggaard, A. M., Schoeters, G., Kolossa-Gehring, M. & Santonen, T., Jun 2019, In : International Journal Of Hygiene And Environmental Health. p. 727-737

Research output: Contribution to journalReview article

Environmental Monitoring
Health
Occupational Health
Body Burden
Food Safety
2 Citations (Scopus)

Insights into the population structure and pan-genome of Haemophilus influenzae

Pinto, M., González-Díaz, A., Machado, M. P., Duarte, S., Vieira, L., Carriço, J. A., Marti, S., Bajanca-Lavado, M. P. & Gomes, J. P., Jan 2019, In : Infection Genetics And Evolution. 67, p. 126-135 10 p.

Research output: Contribution to journalArticle

Haemophilus influenzae
Genome
Haemophilus influenzae type b
Population
Single Nucleotide Polymorphism
1 Citation (Scopus)
Plasticizers
Cytotoxicity
Cells
Liver
DNA-Formamidopyrimidine Glycosylase
Open Access
Absenteeism
Health Services Accessibility
Food Supply
food
health care
Open Access
File
MicroRNAs
Drug Resistance
Neoplasms
Small Untranslated RNA
3' Untranslated Regions
Open Access
File
MicroRNAs
Drug Resistance
Doxorubicin
Breast Neoplasms
Real-Time Polymerase Chain Reaction

Setting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromium

Santonen, T., Alimonti, A., Bocca, B., Duca, R. C., Galea, K. S., Godderis, L., Göen, T., Gomes, B., Hanser, O., Iavicoli, I., Janasik, B., Jones, K., Kiilunen, M., Koch, H. M., Leese, E., Leso, V., Louro, H., Ndaw, S., Porras, S. P., Robert, A. & 7 othersRuggieri, F., Scheepers, P. T. J., Silva, M. J., Viegas, S., Wasowicz, W., Castano, A. & Sepai, O., 1 Oct 2019, In : Environmental Research. 108583.

Research output: Contribution to journalArticle

Environmental Monitoring
occupational exposure
biomonitoring
Occupational Exposure
chromium
1 Citation (Scopus)

Systematic review on recent potential biomarkers of chronic obstructive pulmonary disease

Aydindogan, E., Penque, D. & Zoidakis, J., 2 Jan 2019, In : Expert Review Of Molecular Diagnostics. 19, 1, p. 37-45 9 p.

Research output: Contribution to journalReview article

Chronic Obstructive Pulmonary Disease
Biomarkers
Proteomics
Disease Progression
Proteins
1 Citation (Scopus)
Philadelphia Chromosome
Genetic Predisposition to Disease
Caspases
Population
Genes

Thyroid cancer: The quest for genetic susceptibility involving dna repair genes

Santos, L. S., Gomes, B. C., Bastos, H. N., Gil, O. M., Azevedo, A. P., Ferreira, T. C., Limbert, E., Silva, S. N. & Rueff, J., 1 Aug 2019, In : Genes. 10, 8, 586.

Research output: Contribution to journalArticle

Genetic Predisposition to Disease
Thyroid Neoplasms
Single Nucleotide Polymorphism
DNA Repair
Genes

Ultra-low coverage nanopore sequencing identifies thousands of structural variants in a tumour genome

Silva, C., Marques, B., Pedro, S., Correia, H. & Vieira, L., Jun 2019, In : Hiv Medicine. 98, 26

Research output: Contribution to journalMeeting Abstract

2018

Atypical haematological presentation in a case of polycythaemia vera with a new variant mutation detected in exon 12: c.1605G>T (p.Met535Ile)

Pita, A. S. A., Azevedo, A. P., Reichert, A., Silva, C. J. P. D., Henriques, V., Mendes, D. S., Reis, A. M. B., Cerqueira, R., Torres, F. & Viana, J. F., Feb 2018, In : Journal of Clinical Pathology. 71, 2, p. 180-184 5 p.

Research output: Contribution to journalArticle

Polycythemia Vera
Exons
Mutation
Polycythemia
Janus Kinase 2
2 Citations (Scopus)

Bisoprolol-induced thrombocytopenia: A case report

Mousinho, F., Mendes, T., Sousa e Santos, P., Azevedo, A. P., Mousinho, G., Malcata, C., Viegas, E., Madureira, B., Falcão, F., Gomes, A. P. & Lima, F., Apr 2018, In : Journal of Clinical Pharmacy and Therapeutics. 43, 2, p. 280-283 4 p.

Research output: Contribution to journalArticle

Bisoprolol
Thrombocytopenia
Pharmaceutical Preparations
Bone Marrow Diseases
Idiopathic Thrombocytopenic Purpura

Concomitant myeloproliferative and lymphoproliferative neoplasms, distinct progenitors: A case report and review of the literature

Mousinho, F., Santos, P. S. E., Azevedo, A. P., Pereira, J. M., Lemos, R., Matos, S., Viana, J. F. & Lima, F., Sep 2018, In : MOLECULAR AND CLINICAL ONCOLOGY. 9, 3, p. 347-349

Research output: Contribution to journalReview article

Concomitant presence of JAK2V617F mutation and BCR-ABL translocation in two patients: A new entity or a variant of myeloproliferative neoplasms (Case report)

Mousinho, F., Azevedo, A. P., Mendes, T., Sousa E Santos, P., Cerqueira, R., Matos, S., Santos, S., Ramos, S., Viana, J. F. & Lima, F., 1 Jul 2018, In : Molecular Medicine Reports. 18, 1, p. 1001-1006 6 p.

Research output: Contribution to journalArticle

Rho Guanine Nucleotide Exchange Factors
GTPase-Activating Proteins
Essential Thrombocythemia
Chromosomes
Protein-Tyrosine Kinases
Carbon Nanotubes
Lung
Biological Phenomena
Biomarkers
Toxicogenetics
4 Downloads (Pure)
Open Access
File
NADPH-Ferrihemoprotein Reductase
Osmolar Concentration
7 Citations (Scopus)

Dissecting whole-genome sequencing-based online tools for predicting resistance in Mycobacterium tuberculosis: can we use them for clinical decision guidance?

Macedo, R., Nunes, A., Portugal, I., Duarte, S., Vieira, L. & Gomes, J. P., May 2018, In : Tuberculosis. 110, p. 44-51 8 p.

Research output: Contribution to journalArticle

Mycobacterium tuberculosis
Tuberculosis
Genome
Computational Biology
Genetic Databases
5 Citations (Scopus)
7 Downloads (Pure)

Down syndrome and microRNAs

Brás, A., Rodrigues, A. S., Gomes, B. & Rueff, J., Jan 2018, In : Biomedical Reports. 8, 1, p. 11-16 6 p.

Research output: Contribution to journalReview article

Open Access
File
Down Syndrome
MicroRNAs
Chromosomes
Pathology
Genes
1 Citation (Scopus)
Critical Pathways
Hydroxyurea
Caspases
DNA Repair
Polymorphism

Evaluating the genotoxicity of cellulose nanofibrils in a co-culture of human lung epithelial cells and monocyte-derived macrophages

Ventura, C., Lourenço, A. F., Sousa-Uva, A., Ferreira, P. J. T. & Silva, M. J., 1 Jul 2018, In : Toxicology Letters. 291, p. 173-183 11 p.

Research output: Contribution to journalArticle

Macrophages
Coculture Techniques
Cellulose
Epithelial Cells
Lung
2 Citations (Scopus)
alternative medicine
herbal medicines
flavorings
Risk assessment
functional foods

Human cytochrome P450 expression in bacteria: Whole-cell high-throughput activity assay for CYP1A2, 2A6 and 3A4

Esteves, F., Campelo, D., Urban, P., Bozonnet, S., Lautier, T., Rueff, J., Truan, G. & Kranendonk, M., Dec 2018, In : Biochemical pharmacology. 158, p. 134-140 7 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP1A2
Cytochromes
Cytochrome P-450 Enzyme System
Assays
Bacteria
1 Citation (Scopus)
4 Downloads (Pure)

Mismatch repair single nucleotide polymorphisms and thyroid cancer susceptibility

Santos, L. S., Silva, S. N., Gil, O. M., Ferreira, T. C., Limbert, E. & Rueff, J., May 2018, In : Oncology Letters. 15, 5, p. 6715-6726 12 p.

Research output: Contribution to journalArticle

Open Access
File
DNA Mismatch Repair
Thyroid Neoplasms
Single Nucleotide Polymorphism
Genotype
Genetic Predisposition to Disease
2 Citations (Scopus)

Molecular epidemiology and risk factors of carbapenemase-producing Enterobacteriaceae isolates in Portuguese hospitals: Results From European survey on carbapenemase-producing Enterobacteriaceae (EuSCAPE)

Manageiro, V., Romão, R., Moura, I. B., Sampaio, D. A., Vieira, L., Ferreira, E. & Caniça, M., 27 Nov 2018, In : Frontiers in Microbiology. 9, NOV, 2834.

Research output: Contribution to journalArticle

Open Access
File
Molecular Epidemiology
Enterobacteriaceae
Escherichia coli
Portugal
Clone Cells
4 Citations (Scopus)

New endoperoxides highly active in vivo and in vitro against artemisinin-resistant Plasmodium falciparum

Lobo, L., Cabral, L. I. L., Sena, M. I., Guerreiro, B., Rodrigues, A. S., De Andrade-Neto, V. F., Cristiano, M. L. S. & Nogueira, F., 3 Apr 2018, In : Malaria Journal. 17, 1, 145.

Research output: Contribution to journalArticle

Open Access
Plasmodium falciparum
Antimalarials
Plasmodium berghei
Parasitemia
Tetraoxanes
4 Downloads (Pure)
Open Access
File
NADPH-Ferrihemoprotein Reductase
hinges
cytochromes
Hinges
Cytochrome P-450 Enzyme System

Quercus based coffee-like beverage: effect of roasting process and functional characterization

Coelho, M., Silva, S., Rodríguez-Alcalá, L. M., Oliveira, A., Costa, E. M., Borges, A., Martins, C., Rodrigues, A. S. & Pintado, M. M. E., Mar 2018, In : Journal of Food Measurement and Characterization. 12, 1, p. 471-479 9 p.

Research output: Contribution to journalArticle

Quercus
Coffee
Beverages
roasting
Fatty acids
3 Citations (Scopus)

Relevance of Physicochemical Characterization of Nanomaterials for Understanding Nano-cellular Interactions

Louro, H., 2018, Cellular and Molecular Toxicology of Nanoparticles . Vol. 1048. p. 123-142 20 p. (Advances in Experimental Medicine and Biology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Nanostructures
Carbon Nanotubes
Uncertainty
Environmental Monitoring
Poisons
126 Downloads (Pure)

Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, Function

Pandey, A. V., Henderson, C. J., Ishii, Y., Kranendonk, M., Backes, W. L. & Zanger, U. M., Jan 2018, Frontiers Media S. A. 152 p. (Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, Function)

Research output: Book/ReportBook

Open Access
File
Proximal Kidney Tubule
Facilitative Glucose Transport Proteins
Accessories
Glucose
Kidney
2017
6 Citations (Scopus)

Analysis of Pelagia noctiluca proteome Reveals a Red Fluorescent Protein, a Zinc Metalloproteinase and a Peroxiredoxin

Frazao, B., Campos, A., Osorio, H., Thomas, B., Leandro, S., Teixeira, A., Vasconcelos, V. & Antunes, A., Apr 2017, In : Protein Journal. 36, 2, p. 77-97 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
5 Downloads (Pure)

BCR-ABL V280G mutation, potential role in imatinib resistance: First case report

Azevedo, A. P., Reichert, A., Afonso, C., Alberca, M. D., Tavares, P. & Lima, F., 2017, In : Clinical Medicine Insights: Oncology. 11, 1179554917702870.

Research output: Contribution to journalArticle

Open Access
File
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Mutation
Disease Management
Drug Resistance
Protein-Tyrosine Kinases
3 Citations (Scopus)
14 Downloads (Pure)
Open Access
File
Genetic Predisposition to Disease
DNA Repair
Alleles
DNA Glycosylases
X-Rays
1 Citation (Scopus)
7 Downloads (Pure)

Editorial: Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, Function

Pandey, A. V., Henderson, C. J., Ishii, Y., Kranendonk, M., Backes, W. L. & Zanger, U. M., 27 Nov 2017, In : Frontiers in Pharmacology. 8, 3 p.

Research output: Contribution to journalEditorial

Open Access
File
1 Citation (Scopus)
14 Downloads (Pure)

Evening and morning alterations in Obstructive Sleep Apnea red blood cell proteome

Feliciano, A., Vaz, F., Valentim-Coelho, C., Torres, V. M., Silva, R., Prosinecki, V., Alexandre, B. M., Almeida, A., Almeida-Marques, C., Carvalho, A. S., Matthiesen, R., Malhotra, A., Pinto, P., Bárbara, C. & Penque, D., Apr 2017, In : Data in brief. 11, p. 103-110 8 p.

Research output: Contribution to journalArticle

Open Access
File
Obstructive Sleep Apnea
Proteome
Erythrocytes
Two-Dimensional Difference Gel Electrophoresis
Proteins
3 Citations (Scopus)

Evening and morning peroxiredoxin-2 redox/oligomeric state changes in obstructive sleep apnea red blood cells: Correlation with polysomnographic and metabolic parameters

Feliciano, A., Vaz, F., Torres, V. M., Valentim-Coelho, C., Silva, R., Prosinecki, V., Alexandre, B. M., Carvalho, A. S., Matthiesen, R., Malhotra, A., Pinto, P., Bárbara, C. & Penque, D., Feb 2017, In : Biochimica Et Biophysica Acta. 1863, 2, p. 621-629 9 p.

Research output: Contribution to journalArticle

Peroxiredoxins
Obstructive Sleep Apnea
Oxidation-Reduction
Erythrocytes
Pressure
5 Citations (Scopus)
p53 Genes
Genetic Predisposition to Disease
Pancreatitis
Single Nucleotide Polymorphism
Oxidative Stress

Hazard assessment of benchmark metallic nanomaterials in alveolar epithelial cells

Saruga, A., Louro, H., Pinhao, M. & Silva, M. J., 20 Oct 2017, In : Toxicology Letters. 280, p. S186-S186 1 p.

Research output: Contribution to journalMeeting Abstract

45 Citations (Scopus)

High throughput toxicity screening and intracellular detection of nanomaterials

Collins, A. R., Annangi, B., Rubio, L., Marcos, R. J., Dorn, M., Merker, C., Estrela-Lopis, I., Cimpan, M. R., Ibrahim, M., Cimpan, E., Ostermann, M., Sauter, A., Yamani, N. E., Shaposhnikov, S., Chevillard, S., Paget, V., Grall, R., Delic, J., de-Cerio, F. G., Suarez-Merino, B. & 13 othersFessard, V., Hogeveen, K. N., Fjellsbø, L. M., Pran, E. R., Brzicova, T., Topinka, J., Silva, M. J., Leite, P. E., Ribeiro, A. R., Granjeiro, J. M., Grafström, R., Prina-Mello, A. & Dusinska, M., Jan 2017, In : Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 9, 1, e1413.

Research output: Contribution to journalReview article

Nanostructures
Nanostructured materials
Toxicity
Screening
Throughput
18 Citations (Scopus)

MAP17 Is a Necessary Activator of Renal Na+/Glucose Cotransporter SGLT2

Coady, M. J., El Tarazi, A., Santer, R., Bissonnette, P., Sasseville, L. J., Calado, J., Lussier, Y., Dumayne, C., Bichet, D. G. & Lapointe, J-Y., Jan 2017, In : Journal Of The American Society Of Nephrology. 28, 1, p. 85-93 8 p.

Research output: Contribution to journalArticle

Kidney
Glucose
A Kinase Anchor Proteins
Sodium-Glucose Transporter 2
Renal Glycosuria